product summary
company name :
Cell Signaling Technology
product type :
antibody
product name :
Nanog (D73G4) XP® Rabbit mAb
catalog :
4903S
quantity :
100 ul
price :
260 USD
clonality :
monoclonal
host :
rabbit
reactivity :
human, mouse
application :
western blot, immunohistochemistry, immunocytochemistry, flow cytometry, immunohistochemistry - paraffin section
more info or order :
Cell Signaling Technology product webpage
citations: 22
Published Application/Species/DilutionReference
  • immunocytochemistry; human; 1:300; fig S1B
Stratigopoulos G, Burnett L, Rausch R, Gill R, Penn D, Skowronski A, et al. Hypomorphism of Fto and Rpgrip1l causes obesity in mice. J Clin Invest. 2016;126:1897-910 pubmed publisher
  • western blot; human; fig 1
Kawamura N, Nimura K, Nagano H, Yamaguchi S, Nonomura N, Kaneda Y. CRISPR/Cas9-mediated gene knockout of NANOG and NANOGP8 decreases the malignant potential of prostate cancer cells. Oncotarget. 2015;6:22361-74 pubmed
  • immunohistochemistry - paraffin section; human; fig 3
Palla A, Piazzolla D, Alcazar N, Canamero M, Grana O, Gomez-Lopez G, et al. The pluripotency factor NANOG promotes the formation of squamous cell carcinomas. Sci Rep. 2015;5:10205 pubmed publisher
  • immunocytochemistry; mouse; 1:800
Ono T, Suzuki Y, Kato Y, Fujita R, Araki T, Yamashita T, et al. A single-cell and feeder-free culture system for monkey embryonic stem cells. PLoS ONE. 2014;9:e88346 pubmed publisher
  • immunocytochemistry; human; 1:200
Krutá M, Šeneklová M, Raška J, Salykin A, Zerzankova L, Pesl M, et al. Mutation frequency dynamics in HPRT locus in culture-adapted human embryonic stem cells and induced pluripotent stem cells correspond to their differentiated counterparts. Stem Cells Dev. 2014;23:2443-54 pubmed publisher
  • immunocytochemistry; human; 1:500
Wilson P, Payne T. Genetic reprogramming of human amniotic cells with episomal vectors: neural rosettes as sentinels in candidate selection for validation assays. Peerj. 2014;2:e668 pubmed publisher
  • immunohistochemistry - paraffin section; human; 1:50; fig 7
  • western blot; mouse; 1:1000; fig 7
Piazzolla D, Palla A, Pantoja C, Canamero M, de Castro I, Ortega S, et al. Lineage-restricted function of the pluripotency factor NANOG in stratified epithelia. Nat Commun. 2014;5:4226 pubmed publisher
  • immunocytochemistry; human; 1:200
Shimamoto A, Kagawa H, Zensho K, Sera Y, Kazuki Y, Osaki M, et al. Reprogramming suppresses premature senescence phenotypes of Werner syndrome cells and maintains chromosomal stability over long-term culture. PLoS ONE. 2014;9:e112900 pubmed publisher
  • immunohistochemistry; human; 1:300
  • western blot; human; 1:1000
Chen W, Ho C, Chang Y, Chen H, Lin C, Ling T, et al. Cancer-associated fibroblasts regulate the plasticity of lung cancer stemness via paracrine signalling. Nat Commun. 2014;5:3472 pubmed publisher
  • immunocytochemistry; human; 1:50
Xie Y, Lu W, Liu S, Yang Q, Carver B, Li E, et al. Crosstalk between nuclear MET and SOX9/β-catenin correlates with castration-resistant prostate cancer. Mol Endocrinol. 2014;28:1629-39 pubmed publisher
  • western blot; human
Zhang J, Espinoza L, Kinders R, Lawrence S, Pfister T, Zhou M, et al. NANOG modulates stemness in human colorectal cancer. Oncogene. 2013;32:4397-405 pubmed publisher
Miyatake Y, Sheehy N, Ikeshita S, Hall W, Kasahara M. Anchorage-dependent multicellular aggregate formation induces CD44 high cancer stem cell-like ATL cells in an NF-κB- and vimentin-dependent manner. Cancer Lett. 2015;357:355-63 pubmed publisher
Chen W, Liu J, Zhang L, Xu H, Guo X, Deng S, et al. Generation of the SCN1A epilepsy mutation in hiPS cells using the TALEN technique. Sci Rep. 2014;4:5404 pubmed publisher
Miettinen M, Wang Z, McCue P, Sarlomo-Rikala M, Rys J, Biernat W, et al. SALL4 expression in germ cell and non-germ cell tumors: a systematic immunohistochemical study of 3215 cases. Am J Surg Pathol. 2014;38:410-20 pubmed publisher
Kregel S, Szmulewitz R, Vander Griend D. The pluripotency factor Nanog is directly upregulated by the androgen receptor in prostate cancer cells. Prostate. 2014;74:1530-43 pubmed publisher
Vuoristo S, Toivonen S, Weltner J, Mikkola M, Ustinov J, Trokovic R, et al. A novel feeder-free culture system for human pluripotent stem cell culture and induced pluripotent stem cell derivation. PLoS ONE. 2013;8:e76205 pubmed publisher
Romorini L, Riva D, Bluguermann C, Videla Richardson G, Scassa M, Sevlever G, et al. Effect of antibiotics against Mycoplasma sp. on human embryonic stem cells undifferentiated status, pluripotency, cell viability and growth. PLoS ONE. 2013;8:e70267 pubmed publisher
Rybak A, Tang D. SOX2 plays a critical role in EGFR-mediated self-renewal of human prostate cancer stem-like cells. Cell Signal. 2013;25:2734-42 pubmed publisher
Kregel S, Kiriluk K, Rosen A, Cai Y, Reyes E, Otto K, et al. Sox2 is an androgen receptor-repressed gene that promotes castration-resistant prostate cancer. PLoS ONE. 2013;8:e53701 pubmed publisher
Chae H, Lee M, Broxmeyer H. 5-Aminoimidazole-4-carboxyamide ribonucleoside induces G(1)/S arrest and Nanog downregulation via p53 and enhances erythroid differentiation. Stem Cells. 2012;30:140-9 pubmed publisher
Ledur P, Villodre E, Paulus R, Cruz L, Flores D, Lenz G. Extracellular ATP reduces tumor sphere growth and cancer stem cell population in glioblastoma cells. Purinergic Signal. 2012;8:39-48 pubmed
Polak U, Hirsch C, Ku S, GOTTESFELD J, Dent S, Napierala M. Selecting and isolating colonies of human induced pluripotent stem cells reprogrammed from adult fibroblasts. J Vis Exp. 2012;: pubmed
product information
SKU :
4903S
Product-Name :
Nanog (D73G4) XP® Rabbit mAb
Size :
100 ul
Price-(USD) :
260 USD
Species-x-Reactivity :
H, (Mk)
Applications :
Flow cytometry
Product-Category :
Developmental Biology
Shipping-Temp :
AMBIENT
Storage-Temp :
-20°C
Product-Type :
Monoclonal Antibody
MW :
42
Host :
Rabbit
Target :
Nanog
Primary-Protein :
NANOG
Alt-Names :
Homeobox protein NANOG,Homeobox transcription factor Nanog,NANOG,Nanog homeobox,hNanog,homeobox transcription factor Nanog-delta 48
more info or order :
Cell Signaling Technology product webpage
company information
Cell Signaling Technology
3 Trask Lane
Danvers, MA 01923
info@cellsignal.com
www.cellsignal.com
8776162355
headquarters: USA
Established in Beverly, MA in 1999, Cell Signaling Technology (CST) is a privately-owned company with over 400 employees worldwide. We are dedicated to providing innovative research tools that are used to help define mechanisms underlying cell function and disease. Since its inception, CST has become the world leader in the production of the highest quality activation-state and total protein antibodies utilized to expand knowledge of cell signaling pathways. Our mission is to deliver the world's highest quality research tools that accelerate progress in biological research and personalized medicine.