product summary
company name :
Cell Signaling Technology
product type :
antibody
product name :
Ajuba Antibody
catalog :
4897
clonality :
polyclonal
host :
rabbit
conjugate :
nonconjugated
reactivity :
human, mouse, rat, dog, cow
application :
western blot, immunohistochemistry, immunocytochemistry, immunoprecipitation, flow cytometry
citations: 7
Published Application/Species/Sample/DilutionReference
  • immunocytochemistry; dog; 1:500; fig s1a
  • western blot; dog; 1:1000; fig s3a
  • immunocytochemistry; human; 1:500; loading ...; fig s1a
  • western blot; human; 1:1000; loading ...; fig 5c
Ibar C, Kirichenko E, Keepers B, Enners E, Fleisch K, Irvine K. Tension-dependent regulation of mammalian Hippo signaling through LIMD1. J Cell Sci. 2018;131: pubmed publisher
  • immunocytochemistry; human; fig s5
Jia H, Song L, Cong Q, Wang J, Xu H, Chu Y, et al. The LIM protein AJUBA promotes colorectal cancer cell survival through suppression of JAK1/STAT1/IFIT2 network. Oncogene. 2017;36:2655-2666 pubmed publisher
  • western blot; human; fig 1
Chen X, Stauffer S, Chen Y, Dong J. Ajuba Phosphorylation by CDK1 Promotes Cell Proliferation and Tumorigenesis. J Biol Chem. 2016;291:14761-72 pubmed publisher
  • immunocytochemistry; human; loading ...; fig 4c
  • immunohistochemistry; human; loading ...; fig 7b
  • western blot; human; loading ...; fig 1a
Tanaka I, Osada H, Fujii M, Fukatsu A, Hida T, Horio Y, et al. LIM-domain protein AJUBA suppresses malignant mesothelioma cell proliferation via Hippo signaling cascade. Oncogene. 2015;34:73-83 pubmed publisher
Jagannathan R, Schimizzi G, Zhang K, Loza A, Yabuta N, Nojima H, et al. AJUBA LIM Proteins Limit Hippo Activity in Proliferating Cells by Sequestering the Hippo Core Kinase Complex in the Cytosol. Mol Cell Biol. 2016;36:2526-42 pubmed publisher
Nola S, Daigaku R, Smolarczyk K, Carstens M, Martin Martin B, LONGMORE G, et al. Ajuba is required for Rac activation and maintenance of E-cadherin adhesion. J Cell Biol. 2011;195:855-71 pubmed publisher
Montoya Durango D, Velu C, Kazanjian A, Rojas M, Jay C, Longmore G, et al. Ajuba functions as a histone deacetylase-dependent co-repressor for autoregulation of the growth factor-independent-1 transcription factor. J Biol Chem. 2008;283:32056-65 pubmed publisher
product information
SKU :
4897S
Product-Name :
Ajuba Antibody
Size :
100 ul
Price-(USD) :
235 USD
Species-x-Reactivity :
H, M, Mk, B, (R)
Applications :
Flow cytometry
Product-Category :
Adhesion/ECM
Shipping-Temp :
AMBIENT
Storage-Temp :
-20°C
Product-Type :
Polyclonal Antibody
MW :
55
Host :
Rabbit
Target :
Ajuba
Primary-Protein :
JUB
Alt-Names :
Ajuba,JUB,MGC15563,Protein ajuba,jub, ajuba homolog (Xenopus laevis)
company information
Cell Signaling Technology
3 Trask Lane
Danvers, MA 01923
info@cellsignal.com
www.cellsignal.com
8776162355
headquarters: USA
Established in Beverly, MA in 1999, Cell Signaling Technology (CST) is a privately-owned company with over 400 employees worldwide. We are dedicated to providing innovative research tools that are used to help define mechanisms underlying cell function and disease. Since its inception, CST has become the world leader in the production of the highest quality activation-state and total protein antibodies utilized to expand knowledge of cell signaling pathways. Our mission is to deliver the world's highest quality research tools that accelerate progress in biological research and personalized medicine.