product summary
company name :
Cell Signaling Technology
product type :
antibody
product name :
Mre11 Antibody
catalog :
4895
clonality :
polyclonal
host :
rabbit
conjugate :
nonconjugated
reactivity :
human, mouse, rat
application :
western blot, immunohistochemistry, immunocytochemistry, immunohistochemistry - frozen section, western blot knockout validation
citations: 12
Published Application/Species/Sample/DilutionReference
  • western blot knockout validation; mouse; fig s1
Hartlerode A, Morgan M, Wu Y, Buis J, Ferguson D. Recruitment and activation of the ATM kinase in the absence of DNA-damage sensors. Nat Struct Mol Biol. 2015;22:736-43 pubmed publisher
  • western blot; human; 1:1000; fig 2
Sun Y, Zheng W, Guo Z, Ju Q, Zhu L, Gao J, et al. A novel TP53 pathway influences the HGS-mediated exosome formation in colorectal cancer. Sci Rep. 2016;6:28083 pubmed publisher
  • western blot; human; fig 1
Tookman L, Browne A, Connell C, Bridge G, Ingemarsdotter C, Dowson S, et al. RAD51 and BRCA2 Enhance Oncolytic Adenovirus Type 5 Activity in Ovarian Cancer. Mol Cancer Res. 2016;14:44-55 pubmed publisher
  • western blot; mouse; fig 6
Wang J, Chen S, Sun C, Chien T, Chern Y. A central role of TRAX in the ATM-mediated DNA repair. Oncogene. 2016;35:1657-70 pubmed publisher
  • immunocytochemistry; mouse; 1:200; fig s3
Schröder Heurich B, Wieland B, Lavin M, Schindler D, Dork T. Protective role of RAD50 on chromatin bridges during abnormal cytokinesis. FASEB J. 2014;28:1331-41 pubmed publisher
Campos León K, Wijendra K, Siddiqa A, Pentland I, Feeney K, Knapman A, et al. Association of Human Papillomavirus 16 E2 with Rad50-Interacting Protein 1 Enhances Viral DNA Replication. J Virol. 2017;91: pubmed publisher
Maachani U, Shankavaram U, Kramp T, Tofilon P, Camphausen K, Tandle A. FOXM1 and STAT3 interaction confers radioresistance in glioblastoma cells. Oncotarget. 2016;7:77365-77377 pubmed publisher
Bais M, Ozdener G, Sonenshein G, Trackman P. Effects of tumor-suppressor lysyl oxidase propeptide on prostate cancer xenograft growth and its direct interactions with DNA repair pathways. Oncogene. 2015;34:1928-37 pubmed publisher
Samba Louaka A, Pereira J, Nahori M, Villiers V, Deriano L, Hamon M, et al. Listeria monocytogenes dampens the DNA damage response. PLoS Pathog. 2014;10:e1004470 pubmed publisher
Adeyemi R, Landry S, Davis M, Weitzman M, Pintel D. Parvovirus minute virus of mice induces a DNA damage response that facilitates viral replication. PLoS Pathog. 2010;6:e1001141 pubmed publisher
Wang H, Zhang X, Wang P, Yu X, Essers J, Chen D, et al. Characteristics of DNA-binding proteins determine the biological sensitivity to high-linear energy transfer radiation. Nucleic Acids Res. 2010;38:3245-51 pubmed publisher
Deng Y, Guo X, Ferguson D, Chang S. Multiple roles for MRE11 at uncapped telomeres. Nature. 2009;460:914-8 pubmed publisher
product information
SKU :
4895S
Product-Name :
Mre11 Antibody
Size :
100 ul
Price-(USD) :
235 USD
Species-x-Reactivity :
H, M, R, Mk
Applications :
Immunohistochemistry (Frozen)
Product-Category :
Cell Cycle / Checkpoint Control
Shipping-Temp :
AMBIENT
Storage-Temp :
-20°C
Product-Type :
Polyclonal Antibody
MW :
81
Host :
Rabbit
Target :
Mre11
Primary-Protein :
MRE11A
Alt-Names :
AT-like disease,ATLD,DNA recombination and repair protein,Double-strand break repair protein MRE11A,HNGS1,MRE11,MRE11 homolog 1,MRE11 homolog A,MRE11 meiotic recombination 11 homolog A (S. cerevisiae),MRE11A,MRE11B,Meiotic recombination 11 homolog 1,Meiotic recombination 11 homolog A,endo/exonuclease Mre11
company information
Cell Signaling Technology
3 Trask Lane
Danvers, MA 01923
info@cellsignal.com
www.cellsignal.com
8776162355
headquarters: USA
Established in Beverly, MA in 1999, Cell Signaling Technology (CST) is a privately-owned company with over 400 employees worldwide. We are dedicated to providing innovative research tools that are used to help define mechanisms underlying cell function and disease. Since its inception, CST has become the world leader in the production of the highest quality activation-state and total protein antibodies utilized to expand knowledge of cell signaling pathways. Our mission is to deliver the world's highest quality research tools that accelerate progress in biological research and personalized medicine.