product summary
company name :
Cell Signaling Technology
product type :
antibody
product name :
NF-κB2 p100/p52 Antibody
catalog :
4882S
quantity :
100 ul
price :
235 USD
clonality :
polyclonal
host :
rabbit
reactivity :
human, mouse, rat
application :
western blot, immunoprecipitation, chromatin immunoprecipitation, immunohistochemistry - frozen section
citations: 10
Published Application/Species/DilutionReference
  • immunohistochemistry - frozen section; human
Noort A, van Zoest K, Weijers E, Koolwijk P, Maracle C, Novack D, et al. NF-κB-inducing kinase is a key regulator of inflammation-induced and tumour-associated angiogenesis. J Pathol. 2014;234:375-85 pubmed publisher
  • chromatin immunoprecipitation; mouse
  • western blot; mouse
Taniguchi R, Fukushima H, Osawa K, Maruyama T, Yasuda H, Weih F, et al. RelB-induced expression of Cot, an MAP3K family member, rescues RANKL-induced osteoclastogenesis in alymphoplasia mice by promoting NF-κB2 processing by IKKα. J Biol Chem. 2014;289:7349-61 pubmed publisher
Vince J, Chau D, Callus B, Wong W, Hawkins C, Schneider P, et al. TWEAK-FN14 signaling induces lysosomal degradation of a cIAP1-TRAF2 complex to sensitize tumor cells to TNFalpha. J Cell Biol. 2008;182:171-84 pubmed publisher
Hasler U, Leroy V, Jeon U, Bouley R, Dimitrov M, Kim J, et al. NF-kappaB modulates aquaporin-2 transcription in renal collecting duct principal cells. J Biol Chem. 2008;283:28095-105 pubmed publisher
Kwong C, Gilman-Sachs A, Beaman K. Tumor-associated a2 vacuolar ATPase acts as a key mediator of cancer-related inflammation by inducing pro-tumorigenic properties in monocytes. J Immunol. 2011;186:1781-9 pubmed publisher
Solt L, Madge L, Orange J, May M. Interleukin-1-induced NF-kappaB activation is NEMO-dependent but does not require IKKbeta. J Biol Chem. 2007;282:8724-33 pubmed
Razani B, Zarnegar B, Ytterberg A, Shiba T, Dempsey P, Ware C, et al. Negative feedback in noncanonical NF-kappaB signaling modulates NIK stability through IKKalpha-mediated phosphorylation. Sci Signal. 2010;3:ra41 pubmed publisher
He J, Zarnegar B, Oganesyan G, Saha S, Yamazaki S, Doyle S, et al. Rescue of TRAF3-null mice by p100 NF-kappa B deficiency. J Exp Med. 2006;203:2413-8 pubmed
Lu Y, Kim I, Lye E, Shen F, Suzuki N, Suzuki S, et al. Differential role for c-Rel and C/EBPbeta/delta in TLR-mediated induction of proinflammatory cytokines. J Immunol. 2009;182:7212-21 pubmed publisher
Zarnegar B, Wang Y, Mahoney D, Dempsey P, Cheung H, He J, et al. Noncanonical NF-kappaB activation requires coordinated assembly of a regulatory complex of the adaptors cIAP1, cIAP2, TRAF2 and TRAF3 and the kinase NIK. Nat Immunol. 2008;9:1371-8 pubmed publisher
product information
SKU :
4882S
Product-Name :
NF-κB2 p100/p52 Antibody
Size :
100 ul
Price-(USD) :
235 USD
Species-x-Reactivity :
H, M, R, Mk
Applications :
Immunoprecipitation
Product-Category :
Immunology and Inflammation
Shipping-Temp :
AMBIENT
Storage-Temp :
-20°C
Product-Type :
Polyclonal Antibody
MW :
52 (mature). 120 (precursor).
Host :
Rabbit
Target :
NFkB2 p100/p52
Primary-Protein :
NFkB-p100
Alt-Names :
DNA-binding factor KBF2,H2TF1,LYT-10,LYT10,Lymphocyte translocation chromosome 10 protein,NFKB2,Nuclear factor NF-kappa-B p100 subunit,Nuclear factor NF-kappa-B p52 subunit,Nuclear factor of kappa light polypeptide gene enhancer in B-cells 2,Oncogene Lyt-10,nuclear factor of kappa light chain gene enhancer in B-cells 2,nuclear factor of kappa light polypeptide gene enhancer in B-cells 2 (p49/p100),p52
company information
Cell Signaling Technology
3 Trask Lane
Danvers, MA 01923
info@cellsignal.com
www.cellsignal.com
8776162355
headquarters: USA
Established in Beverly, MA in 1999, Cell Signaling Technology (CST) is a privately-owned company with over 400 employees worldwide. We are dedicated to providing innovative research tools that are used to help define mechanisms underlying cell function and disease. Since its inception, CST has become the world leader in the production of the highest quality activation-state and total protein antibodies utilized to expand knowledge of cell signaling pathways. Our mission is to deliver the world's highest quality research tools that accelerate progress in biological research and personalized medicine.