product summary
company name :
Cell Signaling Technology
product type :
antibody
product name :
HSP90 Antibody
catalog :
4874
clonality :
polyclonal
host :
domestic rabbit
conjugate :
nonconjugated
reactivity :
human, mouse, rat, bovine, Drosophila melanogaster
application :
western blot, immunohistochemistry, flow cytometry, immunohistochemistry - paraffin section
citations: 20
Published Application/Species/Sample/DilutionReference
  • western blot; mouse; 1:1000; loading ...; fig 1f
Sharma A, Oonthonpan L, Sheldon R, Rauckhorst A, Zhu Z, Tompkins S, et al. Impaired skeletal muscle mitochondrial pyruvate uptake rewires glucose metabolism to drive whole-body leanness. elife. 2019;8: pubmed publisher
  • western blot; mouse; 1 ug/ml; loading ...; fig s9a
Sweere J, Van Belleghem J, Ishak H, Bach M, Popescu M, Sunkari V, et al. Bacteriophage trigger antiviral immunity and prevent clearance of bacterial infection. Science. 2019;363: pubmed publisher
  • western blot; mouse; loading ...; fig s6d, s5b
Ganeshan K, Nikkanen J, Man K, Leong Y, Sogawa Y, Maschek J, et al. Energetic Trade-Offs and Hypometabolic States Promote Disease Tolerance. Cell. 2019;: pubmed publisher
  • western blot; mouse; 1:2000; loading ...; fig 6a
Liu R, Jagannathan R, Li F, Lee J, Balasubramanyam N, Kim B, et al. Tead1 is required for perinatal cardiomyocyte proliferation. PLoS ONE. 2019;14:e0212017 pubmed publisher
  • western blot; mouse; loading ...; fig 3a
Zhao T, Hong Y, Yin P, Li S, Li X. Differential HspBP1 expression accounts for the greater vulnerability of neurons than astrocytes to misfolded proteins. Proc Natl Acad Sci U S A. 2017;114:E7803-E7811 pubmed publisher
  • western blot; human; fig 1
Zhou Q, Yu X, Demirkaya E, Deuitch N, Stone D, Tsai W, et al. Biallelic hypomorphic mutations in a linear deubiquitinase define otulipenia, an early-onset autoinflammatory disease. Proc Natl Acad Sci U S A. 2016;113:10127-32 pubmed publisher
  • western blot; human; fig 4
Ah Koon L, Lesage D, Lemadre E, Souissi I, Fagard R, Varin Blank N, et al. Cellular response to alkylating agent MNNG is impaired in STAT1-deficients cells. J Cell Mol Med. 2016;20:1956-65 pubmed publisher
  • western blot; Drosophila melanogaster; 1:1000
Williams A, Mehler V, Mueller C, Vonhoff F, White R, Duch C. Apoptotic Activity of MeCP2 Is Enhanced by C-Terminal Truncating Mutations. PLoS ONE. 2016;11:e0159632 pubmed publisher
  • western blot; human; 1:1000; loading ...; fig 3a
Torrano V, Valcarcel Jimenez L, Cortazar A, Liu X, Urosevic J, Castillo Martin M, et al. The metabolic co-regulator PGC1α suppresses prostate cancer metastasis. Nat Cell Biol. 2016;18:645-656 pubmed publisher
  • flow cytometry; human; 1:25; fig 1b
  • immunohistochemistry; human; loading ...; fig 1a
  • western blot; human; 1:500; fig 1d
Venkatesan N, Kanwar J, Deepa P, Navaneethakrishnan S, Joseph C, Krishnakumar S. Targeting HSP90/Survivin using a cell permeable structure based peptido-mimetic shepherdin in retinoblastoma. Chem Biol Interact. 2016;252:141-9 pubmed publisher
  • western blot; mouse; 1:1000; loading ...; fig 1c
Gray L, Rauckhorst A, Taylor E. A Method for Multiplexed Measurement of Mitochondrial Pyruvate Carrier Activity. J Biol Chem. 2016;291:7409-17 pubmed publisher
Rollins D, Kharlyngdoh J, Coppo M, Tharmalingam B, Mimouna S, Guo Z, et al. Glucocorticoid-induced phosphorylation by CDK9 modulates the coactivator functions of transcriptional cofactor GRIP1 in macrophages. Nat Commun. 2017;8:1739 pubmed publisher
Mar B, Chu S, Kahn J, Krivtsov A, Koche R, Castellano C, et al. SETD2 alterations impair DNA damage recognition and lead to resistance to chemotherapy in leukemia. Blood. 2017;130:2631-2641 pubmed publisher
Lefebure M, Tothill R, Kruse E, Hawkins E, Shortt J, Matthews G, et al. Genomic characterisation of Eμ-Myc mouse lymphomas identifies Bcor as a Myc co-operative tumour-suppressor gene. Nat Commun. 2017;8:14581 pubmed publisher
Jarad M, Kuczynski E, Morrison J, Viloria Petit A, Coomber B. Release of endothelial cell associated VEGFR2 during TGF-β modulated angiogenesis in vitro. BMC Cell Biol. 2017;18:10 pubmed publisher
Arentsen T, Qian Y, Gkotzis S, Femenía T, Wang T, Udekwu K, et al. The bacterial peptidoglycan-sensing molecule Pglyrp2 modulates brain development and behavior. Mol Psychiatry. 2017;22:257-266 pubmed publisher
Fritsch J, Fickers R, Klawitter J, Särchen V, Zingler P, Adam D, et al. TNF induced cleavage of HSP90 by cathepsin D potentiates apoptotic cell death. Oncotarget. 2016;7:75774-75789 pubmed publisher
Jiang Y, Saga K, Miyamoto Y, Kaneda Y. Cytoplasmic calcium increase via fusion with inactivated Sendai virus induces apoptosis in human multiple myeloma cells by downregulation of c-Myc oncogene. Oncotarget. 2016;7:36034-36048 pubmed publisher
Unachukwu U, Warren A, Li Z, Mishra S, Zhou J, Sauane M, et al. Predicted molecular signaling guiding photoreceptor cell migration following transplantation into damaged retina. Sci Rep. 2016;6:22392 pubmed publisher
Xu X, Bao Q, Jia J, Liu F, Guo X, Zhang M, et al. CPUY201112, a novel synthetic small-molecule compound and inhibitor of heat shock protein Hsp90, induces p53-mediated apoptosis in MCF-7 cells. Sci Rep. 2016;6:19004 pubmed publisher
product information
SKU :
4874S
Product-Name :
HSP90 Antibody
Size :
100 ul
Price-(USD) :
235 USD
Species-x-Reactivity :
H, M, R, Mk, Dm, Z, (C, B)
Applications :
Immunohistochemistry (Paraffin)
Product-Category :
Protein Folding and Trafficking
Shipping-Temp :
AMBIENT
Storage-Temp :
-20°C
Product-Type :
Polyclonal Antibody
MW :
90
Host :
Rabbit
Target :
HSP90A/HSP90B
company information
Cell Signaling Technology
3 Trask Lane
Danvers, MA 01923
info@cellsignal.com
https://www.cellsignal.com
8776162355
headquarters: USA
Established in Beverly, MA in 1999, Cell Signaling Technology (CST) is a privately-owned company with over 400 employees worldwide. We are dedicated to providing innovative research tools that are used to help define mechanisms underlying cell function and disease. Since its inception, CST has become the world leader in the production of the highest quality activation-state and total protein antibodies utilized to expand knowledge of cell signaling pathways. Our mission is to deliver the world's highest quality research tools that accelerate progress in biological research and personalized medicine.