HSP70 (6B3) Rat mAb | Cell Signaling Technology 4873 product information

product summary

company name :

Cell Signaling Technology

product type :

antibody

product name :

HSP70 (6B3) Rat mAb

catalog :

4873

clonality :

monoclonal

host :

rat

conjugate :

nonconjugated

clone name :

6B3

reactivity :

human, mouse, rat

application :

western blot, immunohistochemistry, immunocytochemistry, immunoprecipitation, flow cytometry, immunohistochemistry - paraffin section

more info or order :

Cell Signaling Technology product webpage

citations: 10

Published Application/Species/Sample/Dilution	Reference
immunocytochemistry; human; 1:50; loading ...; fig 6e western blot; human; 1:1000; loading ...; fig 6a	Tamaki Y, Shodai A, Morimura T, Hikiami R, Minamiyama S, Ayaki T, et al. Elimination of TDP-43 inclusions linked to amyotrophic lateral sclerosis by a misfolding-specific intrabody with dual proteolytic signals. Sci Rep. 2018;8:6030 pubmed publisher
western blot; human; loading ...; fig 2a	Chen C, Zhuang Y, Chen X, Chen X, Li D, Fan Y, et al. Hsp90 N- and C-terminal double inhibition synergistically suppresses Bcr-Abl-positive human leukemia cells. Oncotarget. 2017;8:10025-10036 pubmed publisher
western blot; mouse; loading ...; fig s2b	Sha L, Wang X, Li J, Shi X, Wu L, Shen Y, et al. Pharmacologic inhibition of Hsp90 to prevent GLT-1 degradation as an effective therapy for epilepsy. J Exp Med. 2017;214:547-563 pubmed publisher
immunohistochemistry - paraffin section; human; 1:100; fig 6 western blot; human; fig 2	Budina Kolomets A, Webster M, Leu J, Jennis M, Krepler C, Guerrini A, et al. HSP70 Inhibition Limits FAK-Dependent Invasion and Enhances the Response to Melanoma Treatment with BRAF Inhibitors. Cancer Res. 2016;76:2720-30 pubmed publisher
western blot; human; fig 3	Bailey C, Budina Kolomets A, Murphy M, Nefedova Y. Efficacy of the HSP70 inhibitor PET-16 in multiple myeloma. Cancer Biol Ther. 2015;16:1422-6 pubmed publisher
western blot; human; fig 7	Artero Castro A, Perez Alea M, Feliciano A, Leal J, Genestar M, Castellvi J, et al. Disruption of the ribosomal P complex leads to stress-induced autophagy. Autophagy. 2015;11:1499-519 pubmed publisher
western blot; rat	Romero J, Hanschmann E, Gellert M, Eitner S, Holubiec M, Blanco Calvo E, et al. Thioredoxin 1 and glutaredoxin 2 contribute to maintain the phenotype and integrity of neurons following perinatal asphyxia. Biochim Biophys Acta. 2015;1850:1274-85 pubmed publisher
western blot; human	Balaburski G, Leu J, Beeharry N, Hayik S, Andrake M, Zhang G, et al. A modified HSP70 inhibitor shows broad activity as an anticancer agent. Mol Cancer Res. 2013;11:219-29 pubmed publisher
	Tracz Gaszewska Z, Klimczak M, Biecek P, Herok M, Kosiński M, Olszewski M, et al. Molecular chaperones in the acquisition of cancer cell chemoresistance with mutated TP53 and MDM2 up-regulation. Oncotarget. 2017;8:82123-82143 pubmed publisher
	Knudsen S, Mac A, Henriksen L, van Deurs B, GrÃ¸vdal L. EGFR signaling patterns are regulated by its different ligands. Growth Factors. 2014;32:155-63 pubmed publisher

product information

SKU :

4873S

Product-Name :

HSP70 (6B3) Rat mAb

Size :

100 ul

Price-(USD) :

235 USD

Species-x-Reactivity :

H, Mk

Applications :

Flow cytometry

Product-Category :

Protein Folding and Trafficking

Shipping-Temp :

AMBIENT

Storage-Temp :

-20°C

Product-Type :

Monoclonal Antibody

MW :

Host :

Rat

Target :

HSP70

Primary-Protein :

HSP70

Alt-Names :

HSP70-1,HSP70-1/HSP70-2,HSP70-1A,HSP70.1/HSP70.2,HSP70I,HSP71,HSP72,HSPA1,HSPA1A,HSPA1B,Heat shock 70 kDa protein 1/2,Heat shock 70 kDa protein 1A/1B,dnaK-type molecular chaperone HSP70-1,heat shock 70kD protein 1A,heat shock 70kDa protein 1A,heat shock-induced protein

more info or order :

Cell Signaling Technology product webpage