product summary
company name :
Cell Signaling Technology
product type :
antibody
product name :
Phospho-DRP1 (Ser637) Antibody
catalog :
4867
clonality :
polyclonal
host :
domestic rabbit
conjugate :
nonconjugated
antigen modification :
phosphorylated
reactivity :
human, mouse, rat
application :
western blot, immunoprecipitation, flow cytometry, immunohistochemistry - paraffin section
more info or order :
Cell Signaling Technology product webpage
citations: 15
Published Application/Species/Sample/DilutionReference
  • western blot; mouse; loading ...; fig 4b
Lee D, Kam M, Lee S, Lee H, Lee D. Peroxiredoxin 5 deficiency exacerbates iron overload-induced neuronal death via ER-mediated mitochondrial fission in mouse hippocampus. Cell Death Dis. 2020;11:204 pubmed publisher
  • western blot; mouse; 1:1000; loading ...; fig 7a
Li T, Li K, Zhang S, Wang Y, Xu Y, Cronin S, et al. Overexpression of apoptosis inducing factor aggravates hypoxic-ischemic brain injury in neonatal mice. Cell Death Dis. 2020;11:77 pubmed publisher
  • western blot; human; 1:1000; loading ...; fig 7a
De R, Sarkar S, Mazumder S, Debsharma S, Siddiqui A, Saha S, et al. Macrophage migration inhibitory factor regulates mitochondrial dynamics and cell growth of human cancer cell lines through CD74-NF-κB signaling. J Biol Chem. 2018;293:19740-19760 pubmed publisher
  • western blot; mouse; loading ...; fig 3e
Du X, Wen J, Wang Y, Karmaus P, Khatamian A, Tan H, et al. Hippo/Mst signalling couples metabolic state and immune function of CD8α+ dendritic cells. Nature. 2018;558:141-145 pubmed publisher
  • western blot; mouse; 1:1000; loading ...; fig 6e
Velázquez Villegas L, Perino A, Lemos V, Zietak M, Nomura M, Pols T, et al. TGR5 signalling promotes mitochondrial fission and beige remodelling of white adipose tissue. Nat Commun. 2018;9:245 pubmed publisher
  • western blot; human; loading ...; fig 6a
Li G, Fu R, Shen H, Zhou J, Hu X, Liu Y, et al. Polyphyllin I induces mitophagic and apoptotic cell death in human breast cancer cells by increasing mitochondrial PINK1 levels. Oncotarget. 2017;8:10359-10374 pubmed publisher
  • flow cytometry; human; fig 4
Jung J, Ravi S, Lee D, McFadden K, Kamradt M, Toussaint L, et al. NIK/MAP3K14 Regulates Mitochondrial Dynamics and Trafficking to Promote Cell Invasion. Curr Biol. 2016;26:3288-3302 pubmed publisher
  • western blot; human; loading ...; fig sf3
Lee J, Westrate L, Wu H, Page C, Voeltz G. Multiple dynamin family members collaborate to drive mitochondrial division. Nature. 2016;540:139-143 pubmed publisher
  • western blot; mouse
El Sikhry H, Alsaleh N, Dakarapu R, Falck J, Seubert J. Novel Roles of Epoxyeicosanoids in Regulating Cardiac Mitochondria. PLoS ONE. 2016;11:e0160380 pubmed publisher
  • immunohistochemistry - paraffin section; rat; 1:500; loading ...; fig 10a
Ko A, Hyun H, Min S, Kim J. The Differential DRP1 Phosphorylation and Mitochondrial Dynamics in the Regional Specific Astroglial Death Induced by Status Epilepticus. Front Cell Neurosci. 2016;10:124 pubmed publisher
  • western blot; rat; 1:1000; fig 4
Hyun H, Ko A, Kang T. Mitochondrial Translocation of High Mobility Group Box 1 Facilitates LIM Kinase 2-Mediated Programmed Necrotic Neuronal Death. Front Cell Neurosci. 2016;10:99 pubmed publisher
  • western blot; human; loading ...; fig s2a
Pryde K, Smith H, Chau K, Schapira A. PINK1 disables the anti-fission machinery to segregate damaged mitochondria for mitophagy. J Cell Biol. 2016;213:163-71 pubmed publisher
  • western blot; rat; 1:500; fig 2
Torres G, Morales P, García Miguel M, Norambuena Soto I, Cartes Saavedra B, Vidal Peña G, et al. Glucagon-like peptide-1 inhibits vascular smooth muscle cell dedifferentiation through mitochondrial dynamics regulation. Biochem Pharmacol. 2016;104:52-61 pubmed publisher
  • western blot; mouse; fig 5
Moriwaki K, Farias Luz N, Balaji S, De Rosa M, O Donnell C, Gough P, et al. The Mitochondrial Phosphatase PGAM5 Is Dispensable for Necroptosis but Promotes Inflammasome Activation in Macrophages. J Immunol. 2016;196:407-15 pubmed publisher
Sun Y, Li T, Xie C, Zhang Y, Zhou K, Wang X, et al. Dichloroacetate treatment improves mitochondrial metabolism and reduces brain injury in neonatal mice. Oncotarget. 2016;7:31708-22 pubmed publisher
product information
SKU :
4867S
Product-Name :
Phospho-DRP1 (Ser637) Antibody
Size :
100 ul
Price-(USD) :
274 USD
Species-x-Reactivity :
R, (M, Mk, Pg)
Applications :
Immunoprecipitation
Product-Category :
Cytoskeletal Signaling
Shipping-Temp :
AMBIENT
Storage-Temp :
-20°C
Product-Type :
Polyclonal Antibody
MW :
78-82
Host :
Rabbit
Target :
DRP1 (Ser637) phosphate
Primary-Protein :
DRP1
Alt-Names :
DLP1,DNM1L,DRP1,DVLP,DYNIV-11,Dnm1p/Vps1p-like protein,Dymple,Dynamin family member proline-rich carboxyl-terminal domain less,Dynamin-1-like protein,Dynamin-like protein,Dynamin-like protein 4,Dynamin-like protein IV,Dynamin-related protein 1,FLJ41912,HdynIV,VPS1,dynamin 1-like
more info or order :
Cell Signaling Technology product webpage
company information
Cell Signaling Technology
3 Trask Lane
Danvers, MA 01923
info@cellsignal.com
https://www.cellsignal.com
8776162355
headquarters: USA
Established in Beverly, MA in 1999, Cell Signaling Technology (CST) is a privately-owned company with over 400 employees worldwide. We are dedicated to providing innovative research tools that are used to help define mechanisms underlying cell function and disease. Since its inception, CST has become the world leader in the production of the highest quality activation-state and total protein antibodies utilized to expand knowledge of cell signaling pathways. Our mission is to deliver the world's highest quality research tools that accelerate progress in biological research and personalized medicine.