product summary
company name :
Cell Signaling Technology
product type :
antibody
product name :
VDAC Antibody
catalog :
4866
clonality :
polyclonal
host :
domestic rabbit
conjugate :
nonconjugated
reactivity :
human, mouse, rat, bovine
application :
western blot, immunohistochemistry, immunohistochemistry - paraffin section, immunohistochemistry - frozen section
citations: 19
Published Application/Species/Sample/DilutionReference
  • western blot; mouse; 1:2000; loading ...; fig 3e
Hoshino A, Wang W, Wada S, McDermott Roe C, Evans C, Gosis B, et al. The ADP/ATP translocase drives mitophagy independent of nucleotide exchange. Nature. 2019;575:375-379 pubmed publisher
  • western blot; mouse; loading ...; fig s3a
Yang S, Harding A, Sweeney C, Miao D, Swan G, Zhou C, et al. Control of antiviral innate immune response by protein geranylgeranylation. Sci Adv. 2019;5:eaav7999 pubmed publisher
  • western blot; human; fig 3g
Park H, Chung K, An H, Gim J, Hong J, Woo H, et al. Parkin Promotes Mitophagic Cell Death in Adult Hippocampal Neural Stem Cells Following Insulin Withdrawal. Front Mol Neurosci. 2019;12:46 pubmed publisher
  • western blot; mouse; 1:1000; loading ...; fig 1d
Walsh T, van den Bosch M, Lewis K, Williams C, Poole A. Loss of the mitochondrial kinase PINK1 does not alter platelet function. Sci Rep. 2018;8:14377 pubmed publisher
  • western blot; human; loading ...; fig 1e
Caino M, Seo J, Wang Y, Rivadeneira D, Gabrilovich D, Kim E, et al. Syntaphilin controls a mitochondrial rheostat for proliferation-motility decisions in cancer. J Clin Invest. 2017;127:3755-3769 pubmed publisher
  • western blot; mouse; loading ...; fig 1c
Nam M, Akie T, Sanosaka M, Craige S, Kant S, Keaney J, et al. Mitochondrial retrograde signaling connects respiratory capacity to thermogenic gene expression. Sci Rep. 2017;7:2013 pubmed publisher
  • western blot; mouse; 1:1000; loading ...; fig 4a
Lee C, Hanna A, Wang H, Dagnino Acosta A, Joshi A, Knoblauch M, et al. A chemical chaperone improves muscle function in mice with a RyR1 mutation. Nat Commun. 2017;8:14659 pubmed publisher
  • western blot; rat; 1:1000; loading ...; fig 6c
Merdzo I, Rutkai I, Sure V, McNulty C, Katakam P, Busija D. Impaired Mitochondrial Respiration in Large Cerebral Arteries of Rats with Type 2 Diabetes. J Vasc Res. 2017;54:1-12 pubmed publisher
  • western blot; human; loading ...; fig 8e
Rohlenova K, Sachaphibulkij K, Stursa J, Bezawork Geleta A, Blecha J, Endaya B, et al. Selective Disruption of Respiratory Supercomplexes as a New Strategy to Suppress Her2high Breast Cancer. Antioxid Redox Signal. 2017;26:84-103 pubmed publisher
  • western blot; rat; 1:3000; fig 5
Wang H, Zhang H, Chen X, Zhao T, Kong Q, Yan M, et al. The decreased expression of electron transfer flavoprotein ? is associated with tubular cell apoptosis in diabetic nephropathy. Int J Mol Med. 2016;37:1290-8 pubmed publisher
  • western blot; mouse; 1:1000; fig 4
Zhao Y, Xu L, Qiao Z, Gao L, Ding S, Ying X, et al. YiXin-Shu, a ShengMai-San-based traditional Chinese medicine formula, attenuates myocardial ischemia/reperfusion injury by suppressing mitochondrial mediated apoptosis and upregulating liver-X-receptor α. Sci Rep. 2016;6:23025 pubmed publisher
  • western blot; rat; 1:1000; fig 6
Merdzo I, Rutkai I, Tokés T, Sure V, Katakam P, Busija D. The mitochondrial function of the cerebral vasculature in insulin-resistant Zucker obese rats. Am J Physiol Heart Circ Physiol. 2016;310:H830-8 pubmed publisher
  • immunohistochemistry - frozen section; rat; fig 2
Shinde V, Kotla P, Strang C, Gorbatyuk M. Unfolded protein response-induced dysregulation of calcium homeostasis promotes retinal degeneration in rat models of autosomal dominant retinitis pigmentosa. Cell Death Dis. 2016;7:e2085 pubmed publisher
  • western blot; mouse; 1:1000; fig 3
Safdar A, Khrapko K, Flynn J, Saleem A, De Lisio M, Johnston A, et al. Exercise-induced mitochondrial p53 repairs mtDNA mutations in mutator mice. Skelet Muscle. 2016;6:7 pubmed publisher
  • western blot; mouse
  • western blot; human
Yoon S, Bogdanov K, Kovalenko A, Wallach D. Necroptosis is preceded by nuclear translocation of the signaling proteins that induce it. Cell Death Differ. 2016;23:253-60 pubmed publisher
Cho J, Zhang Y, Park S, Joseph A, Han C, Park H, et al. Mitochondrial ATP transporter depletion protects mice against liver steatosis and insulin resistance. Nat Commun. 2017;8:14477 pubmed publisher
Sun Z, Zhan L, Liang L, Sui H, Zheng L, Sun X, et al. ZiBu PiYin recipe prevents diabetes-associated cognitive decline in rats: possible involvement of ameliorating mitochondrial dysfunction, insulin resistance pathway and histopathological changes. BMC Complement Altern Med. 2016;16:200 pubmed publisher
Burkart A, Tan K, Warren L, Iovino S, Hughes K, Kahn C, et al. Insulin Resistance in Human iPS Cells Reduces Mitochondrial Size and Function. Sci Rep. 2016;6:22788 pubmed publisher
Stine R, Shapira S, Lim H, Ishibashi J, Harms M, Won K, et al. EBF2 promotes the recruitment of beige adipocytes in white adipose tissue. Mol Metab. 2016;5:57-65 pubmed publisher
product information
SKU :
4866S
Product-Name :
VDAC Antibody
Size :
100 ul
Price-(USD) :
235 USD
Species-x-Reactivity :
H, M, R, B
Applications :
Immunohistochemistry (Paraffin)
Product-Category :
Apoptosis
Shipping-Temp :
AMBIENT
Storage-Temp :
-20°C
Product-Type :
Polyclonal Antibody
MW :
32
Host :
Rabbit
Target :
VDAC1
Primary-Protein :
VDAC1
Alt-Names :
MGC111064,Outer mitochondrial membrane protein porin 1,PORIN,PORIN-31-HL,Plasmalemmal porin,Porin 31HL,Porin 31HM,VDAC,VDAC-1,VDAC1,Voltage-dependent anion-selective channel protein 1,hVDAC1,voltage-dependent anion channel 1
company information
Cell Signaling Technology
3 Trask Lane
Danvers, MA 01923
info@cellsignal.com
https://www.cellsignal.com
8776162355
headquarters: USA
Established in Beverly, MA in 1999, Cell Signaling Technology (CST) is a privately-owned company with over 400 employees worldwide. We are dedicated to providing innovative research tools that are used to help define mechanisms underlying cell function and disease. Since its inception, CST has become the world leader in the production of the highest quality activation-state and total protein antibodies utilized to expand knowledge of cell signaling pathways. Our mission is to deliver the world's highest quality research tools that accelerate progress in biological research and personalized medicine.