product summary
company name :
Cell Signaling Technology
product type :
antibody
product name :
Phospho-S6 Ribosomal Protein (Ser235/236) (2F9) Rabbit mAb
catalog :
4856S
quantity :
100 ul
price :
274 USD
clonality :
monoclonal
host :
rabbit
antigen modification :
phosphorylated
clone name :
2F9
reactivity :
human, mouse, rat, dog
application :
western blot, immunohistochemistry, immunocytochemistry, flow cytometry, immunohistochemistry - paraffin section
more info or order :
Cell Signaling Technology product webpage
citations: 18
Published Application/Species/DilutionReference
  • western blot; human; 1:1000; fig 6
Dirks M, Wall B, Kramer I, Zorenc A, Goessens J, Gijsen A, et al. A single session of neuromuscular electrical stimulation does not augment postprandial muscle protein accretion. Am J Physiol Endocrinol Metab. 2016;311:E278-85 pubmed publisher
  • western blot; mouse; 1:1000; fig 9a
Shih Y, Hsueh Y. VCP and ATL1 regulate endoplasmic reticulum and protein synthesis for dendritic spine formation. Nat Commun. 2016;7:11020 pubmed publisher
  • western blot; mouse; 1:1000; fig 3
Hakim S, Dyson J, Feeney S, Davies E, Sriratana A, Koenig M, et al. Inpp5e suppresses polycystic kidney disease via inhibition of PI3K/Akt-dependent mTORC1 signaling. Hum Mol Genet. 2016;25:2295-2313 pubmed
  • western blot; human; 1:1000; fig 4
Papke B, Murarka S, Vogel H, Martín-Gago P, Kovacevic M, Truxius D, et al. Identification of pyrazolopyridazinones as PDEδ inhibitors. Nat Commun. 2016;7:11360 pubmed publisher
  • western blot; human; fig 2
Vogel C, Smit M, Maddalo G, Possik P, Sparidans R, van der Burg S, et al. Cooperative induction of apoptosis in NRAS mutant melanoma by inhibition of MEK and ROCK. Pigment Cell Melanoma Res. 2015;28:307-17 pubmed publisher
  • western blot; human; fig 2
Kemmerer M, Finkernagel F, Cavalcante M, Abdalla D, Muller R, Brüne B, et al. AMP-Activated Protein Kinase Interacts with the Peroxisome Proliferator-Activated Receptor Delta to Induce Genes Affecting Fatty Acid Oxidation in Human Macrophages. PLoS ONE. 2015;10:e0130893 pubmed publisher
  • immunocytochemistry; human
Ren H, Wang J, Yang F, Zhang X, Wang A, Sun L, et al. Cytoplasmic TRAF4 contributes to the activation of p70s6k signaling pathway in breast cancer. Oncotarget. 2015;6:4080-96 pubmed
  • immunohistochemistry - paraffin section; dog
  • western blot; dog
Andersen N, Boguslawski E, Kuk C, Chambers C, Duesbery N. Combined inhibition of MEK and mTOR has a synergic effect on angiosarcoma tumorgrafts. Int J Oncol. 2015;47:71-80 pubmed publisher
  • immunohistochemistry; mouse; 1:300; fig 2
Venkatesh A, Ma S, Le Y, Hall M, Ruegg M, Punzo C. Activated mTORC1 promotes long-term cone survival in retinitis pigmentosa mice. J Clin Invest. 2015;125:1446-58 pubmed publisher
  • western blot; mouse; fig 7
Shrestha S, Yang K, Guy C, Vogel P, Neale G, Chi H. Treg cells require the phosphatase PTEN to restrain TH1 and TFH cell responses. Nat Immunol. 2015;16:178-87 pubmed publisher
  • western blot; human; fig 1
Yi Y, Kang H, Bae E, Oh S, Seong Y, Bae I. β-TrCP1 degradation is a novel action mechanism of PI3K/mTOR inhibitors in triple-negative breast cancer cells. Exp Mol Med. 2015;47:e143 pubmed publisher
  • flow cytometry; mouse
Carty S, Koretzky G, Jordan M. Interleukin-4 regulates eomesodermin in CD8+ T cell development and differentiation. PLoS ONE. 2014;9:e106659 pubmed publisher
  • western blot; mouse; 1:1000
Areta J, Hawley J, Ye J, Chan M, Coffey V. Increasing leucine concentration stimulates mechanistic target of rapamycin signaling and cell growth in C2C12 skeletal muscle cells. Nutr Res. 2014;34:1000-7 pubmed publisher
  • western blot; rat
Rodriguez-Martin T, Cuchillo-Ibanez I, Noble W, Nyenya F, Anderton B, Hanger D. Tau phosphorylation affects its axonal transport and degradation. Neurobiol Aging. 2013;34:2146-57 pubmed publisher
  • western blot; human
Areta J, Burke L, Ross M, Camera D, West D, Broad E, et al. Timing and distribution of protein ingestion during prolonged recovery from resistance exercise alters myofibrillar protein synthesis. J Physiol. 2013;591:2319-31 pubmed publisher
Mennigen J, Panserat S, Larquier M, Plagnes-Juan E, Médale F, Seiliez I, et al. Postprandial regulation of hepatic microRNAs predicted to target the insulin pathway in rainbow trout. PLoS ONE. 2012;7:e38604 pubmed publisher
Kotecha N, Flores N, Irish J, Simonds E, Sakai D, Archambeault S, et al. Single-cell profiling identifies aberrant STAT5 activation in myeloid malignancies with specific clinical and biologic correlates. Cancer Cell. 2008;14:335-43 pubmed publisher
Vernier S, Chiu A, Schober J, Weber T, Nguyen P, LUER M, et al. β-cell metabolic alterations under chronic nutrient overload in rat and human islets. Islets. 2012;4:379-92 pubmed publisher
product information
SKU :
4856S
Product-Name :
Phospho-S6 Ribosomal Protein (Ser235/236) (2F9) Rabbit mAb
Size :
100 ul
Price-(USD) :
274 USD
Species-x-Reactivity :
H, M, R, Mk
Applications :
Flow cytometry
Product-Category :
Translational Control
Shipping-Temp :
COLD
Storage-Temp :
-20°C
Product-Type :
Monoclonal Antibody
MW :
32
Host :
Rabbit
Target :
S6 Ribosomal Protein (Ser235/Ser236) phosphate
Primary-Protein :
S6
Alt-Names :
40S ribosomal protein S6,Phosphoprotein NP33,RPS6,RS6,ribosomal protein S6
more info or order :
Cell Signaling Technology product webpage
company information
Cell Signaling Technology
3 Trask Lane
Danvers, MA 01923
info@cellsignal.com
www.cellsignal.com
8776162355
headquarters: USA
Established in Beverly, MA in 1999, Cell Signaling Technology (CST) is a privately-owned company with over 400 employees worldwide. We are dedicated to providing innovative research tools that are used to help define mechanisms underlying cell function and disease. Since its inception, CST has become the world leader in the production of the highest quality activation-state and total protein antibodies utilized to expand knowledge of cell signaling pathways. Our mission is to deliver the world's highest quality research tools that accelerate progress in biological research and personalized medicine.