product summary
company name :
Cell Signaling Technology
product type :
antibody
product name :
COX IV Antibody
catalog :
4844S
quantity :
100 ul
price :
235 USD
clonality :
polyclonal
host :
rabbit
reactivity :
baboons, human, mouse, rat, cow
application :
western blot, immunohistochemistry, immunocytochemistry, immunoprecipitation, flow cytometry
more info or order :
Cell Signaling Technology product webpage
citations: 18
Published Application/Species/DilutionReference
  • western blot; human; 1:100; fig 3
Mukherjee R, Chakrabarti O. Ubiquitin-mediated regulation of the E3 ligase GP78 by MGRN1 in trans affects mitochondrial homeostasis. J Cell Sci. 2016;129:757-73 pubmed publisher
  • western blot; mouse; 1:1000; fig 2
Chen Y, Pandiri I, Joe Y, Kim H, Kim S, Park J, et al. Synergistic Effects of Cilostazol and Probucol on ER Stress-Induced Hepatic Steatosis via Heme Oxygenase-1-Dependent Activation of Mitochondrial Biogenesis. Oxid Med Cell Longev. 2016;2016:3949813 pubmed publisher
  • immunohistochemistry; rat; 1:400
Requena T, Cabrera S, Martín-Sierra C, Price S, Lysakowski A, Lopez-Escamez J. Identification of two novel mutations in FAM136A and DTNA genes in autosomal-dominant familial Meniere's disease. Hum Mol Genet. 2015;24:1119-26 pubmed publisher
  • western blot; human; fig 1b
  • western blot; mouse; fig 1c
Liu R, Fan M, Candas D, Qin L, Zhang X, Eldridge A, et al. CDK1-Mediated SIRT3 Activation Enhances Mitochondrial Function and Tumor Radioresistance. Mol Cancer Ther. 2015;14:2090-102 pubmed publisher
  • western blot; rat; fig 10
Salabei J, Gibb A, Hill B. Comprehensive measurement of respiratory activity in permeabilized cells using extracellular flux analysis. Nat Protoc. 2014;9:421-38 pubmed publisher
  • western blot; baboons; 1:1000; fig 2
Tchoukalova Y, Krishnapuram R, White U, Burk D, Fang X, Nijland M, et al. Fetal baboon sex-specific outcomes in adipocyte differentiation at 0.9 gestation in response to moderate maternal nutrient reduction. Int J Obes (Lond). 2014;38:224-30 pubmed publisher
Lu C, Qin L, Liu H, Candas D, Fan M, Li J. Tumor cells switch to mitochondrial oxidative phosphorylation under radiation via mTOR-mediated hexokinase II inhibition--a Warburg-reversing effect. PLoS ONE. 2015;10:e0121046 pubmed publisher
Hernandez G, Thornton C, Stotland A, Lui D, Sin J, Ramil J, et al. MitoTimer: a novel tool for monitoring mitochondrial turnover. Autophagy. 2013;9:1852-61 pubmed publisher
Zhao L, He F, Liu H, Zhu Y, Tian W, Gao P, et al. Natural diterpenoid compound elevates expression of Bim protein, which interacts with antiapoptotic protein Bcl-2, converting it to proapoptotic Bax-like molecule. J Biol Chem. 2012;287:1054-65 pubmed publisher
Li B, Shin J, Lee K. Interferon-stimulated gene ISG12b1 inhibits adipogenic differentiation and mitochondrial biogenesis in 3T3-L1 cells. Endocrinology. 2009;150:1217-24 pubmed publisher
Csiszar A, Labinskyy N, Orosz Z, Xiangmin Z, Buffenstein R, Ungvari Z. Vascular aging in the longest-living rodent, the naked mole rat. Am J Physiol Heart Circ Physiol. 2007;293:H919-27 pubmed
Ye B, Kroboth S, Pu J, Sims J, Aggarwal N, McNally E, et al. Molecular identification and functional characterization of a mitochondrial sulfonylurea receptor 2 splice variant generated by intraexonic splicing. Circ Res. 2009;105:1083-93 pubmed publisher
Widenmaier S, Ao Z, Kim S, Warnock G, McIntosh C. Suppression of p38 MAPK and JNK via Akt-mediated inhibition of apoptosis signal-regulating kinase 1 constitutes a core component of the beta-cell pro-survival effects of glucose-dependent insulinotropic polypeptide. J Biol Chem. 2009;284:30372-82 pubmed publisher
Endo H, Saito A, Chan P. Mitochondrial translocation of p53 underlies the selective death of hippocampal CA1 neurons after global cerebral ischaemia. Biochem Soc Trans. 2006;34:1283-6 pubmed
Bhowmick R, Halder U, Chattopadhyay S, Chanda S, Nandi S, Bagchi P, et al. Rotaviral enterotoxin nonstructural protein 4 targets mitochondria for activation of apoptosis during infection. J Biol Chem. 2012;287:35004-20 pubmed publisher
Panduri V, Surapureddi S, Soberanes S, Weitzman S, Chandel N, Kamp D. P53 mediates amosite asbestos-induced alveolar epithelial cell mitochondria-regulated apoptosis. Am J Respir Cell Mol Biol. 2006;34:443-52 pubmed
Steckley D, Karajgikar M, Dale L, Fuerth B, Swan P, Drummond-Main C, et al. Puma is a dominant regulator of oxidative stress induced Bax activation and neuronal apoptosis. J Neurosci. 2007;27:12989-99 pubmed
Ungvari Z, Labinskyy N, Gupte S, Chander P, Edwards J, Csiszar A. Dysregulation of mitochondrial biogenesis in vascular endothelial and smooth muscle cells of aged rats. Am J Physiol Heart Circ Physiol. 2008;294:H2121-8 pubmed publisher
product information
SKU :
4844S
Product-Name :
COX IV Antibody
Size :
100 ul
Price-(USD) :
235 USD
Species-x-Reactivity :
H, M, R, Mk, B
Applications :
Flow cytometry
Product-Category :
Metabolism
Shipping-Temp :
AMBIENT
Storage-Temp :
-20°C
Product-Type :
Polyclonal Antibody
MW :
17
Host :
Rabbit
Target :
COX IV
Primary-Protein :
COX4I1
Alt-Names :
COX IV-1,COX4,COX41,COX4I1,COXIV,Cytochrome c oxidase polypeptide IV,Cytochrome c oxidase subunit 4 isoform 1, mitochondrial,Cytochrome c oxidase subunit IV isoform 1,MGC72016
more info or order :
Cell Signaling Technology product webpage
company information
Cell Signaling Technology
3 Trask Lane
Danvers, MA 01923
info@cellsignal.com
www.cellsignal.com
8776162355
headquarters: USA
Established in Beverly, MA in 1999, Cell Signaling Technology (CST) is a privately-owned company with over 400 employees worldwide. We are dedicated to providing innovative research tools that are used to help define mechanisms underlying cell function and disease. Since its inception, CST has become the world leader in the production of the highest quality activation-state and total protein antibodies utilized to expand knowledge of cell signaling pathways. Our mission is to deliver the world's highest quality research tools that accelerate progress in biological research and personalized medicine.