product summary
company name :
Cell Signaling Technology
product type :
antibody
product name :
COX IV Antibody
catalog :
4844
clonality :
polyclonal
host :
domestic rabbit
conjugate :
nonconjugated
reactivity :
human, mouse, rat, bovine
application :
western blot, immunohistochemistry, immunocytochemistry, immunoprecipitation, flow cytometry, immunohistochemistry - paraffin section
citations: 30
Published Application/Species/Sample/DilutionReference
  • western blot; mouse; fig s1d
Lim Y, Kim S, Kim E. Palmitate reduces starvation-induced ER stress by inhibiting ER-phagy in hypothalamic cells. Mol Brain. 2021;14:65 pubmed publisher
  • western blot; rat; loading ...; fig 5b
Xu Y, Zhi F, Mao J, Peng Y, Shao N, Balboni G, et al. δ-opioid receptor activation protects against Parkinson's disease-related mitochondrial dysfunction by enhancing PINK1/Parkin-dependent mitophagy. Aging (Albany NY). 2020;12:25035-25059 pubmed publisher
  • western blot; mouse; loading ...; fig 5s1a
Marmol P, Krapacher F, Ibanez C. Control of brown adipose tissue adaptation to nutrient stress by the activin receptor ALK7. elife. 2020;9: pubmed publisher
  • western blot; human; 1:1000; loading ...; fig s5a
Singh C, Tran V, McCollum L, Bolok Y, Allan K, Yuan A, et al. Hyperoxia induces glutamine-fuelled anaplerosis in retinal Müller cells. Nat Commun. 2020;11:1277 pubmed publisher
  • western blot; mouse; 1:1000; loading ...; fig 3b
Zuo Z, Liu Z, Gao T, Yin Y, Wang Z, Hou Y, et al. Prolonged inorganic arsenic exposure via drinking water impairs brown adipose tissue function in mice. Sci Total Environ. 2019;668:310-317 pubmed publisher
  • western blot; mouse; 1:1000; fig 3b
Shi Y, Lim S, Liang Q, Iyer S, Wang H, Wang Z, et al. Gboxin is an oxidative phosphorylation inhibitor that targets glioblastoma. Nature. 2019;567:341-346 pubmed publisher
  • western blot; mouse; 1:2000; loading ...; fig 1h
Zhang Z, Zi Z, Lee E, Zhao J, Contreras D, South A, et al. Differential glucose requirement in skin homeostasis and injury identifies a therapeutic target for psoriasis. Nat Med. 2018;24:617-627 pubmed publisher
  • western blot; rat; loading ...; fig 1b
Blunsom N, Gomez Espinosa E, Ashlin T, Cockcroft S. Mitochondrial CDP-diacylglycerol synthase activity is due to the peripheral protein, TAMM41 and not due to the integral membrane protein, CDP-diacylglycerol synthase 1. Biochim Biophys Acta Mol Cell Biol Lipids. 2018;1863:284-298 pubmed publisher
  • western blot; mouse; 1:1000; loading ...; fig 4a
Lee C, Hanna A, Wang H, Dagnino Acosta A, Joshi A, Knoblauch M, et al. A chemical chaperone improves muscle function in mice with a RyR1 mutation. Nat Commun. 2017;8:14659 pubmed publisher
  • western blot; human; 1:500; loading ...; fig 1d
Jia X, Chen J, Megger D, Zhang X, Kozlowski M, Zhang L, et al. Label-free Proteomic Analysis of Exosomes Derived from Inducible Hepatitis B Virus-Replicating HepAD38 Cell Line. Mol Cell Proteomics. 2017;16:S144-S160 pubmed publisher
  • western blot; human; loading ...; fig 6d
Mandl M, Zhang S, Ulrich M, Schmoeckel E, Mayr D, Vollmar A, et al. Inhibition of Cdk5 induces cell death of tumor-initiating cells. Br J Cancer. 2017;116:912-922 pubmed publisher
  • western blot; mouse; loading ...; fig 2e
Kang S, Yi H, Choi M, Ryu M, Jung S, Chung H, et al. ANGPTL6 expression is coupled with mitochondrial OXPHOS function to regulate adipose FGF21. J Endocrinol. 2017;233:105-118 pubmed publisher
  • western blot; mouse; 1:1000; loading ...; fig 1b
Shen Z, Zheng Y, Wu J, Chen Y, Wu X, Zhou Y, et al. PARK2-dependent mitophagy induced by acidic postconditioning protects against focal cerebral ischemia and extends the reperfusion window. Autophagy. 2017;13:473-485 pubmed publisher
  • immunohistochemistry - paraffin section; mouse; loading ...; fig s2a
  • western blot; mouse; loading ...; fig s2b
Ugun Klusek A, Tatham M, Elkharaz J, Constantin Teodosiu D, Lawler K, Mohamed H, et al. Continued 26S proteasome dysfunction in mouse brain cortical neurons impairs autophagy and the Keap1-Nrf2 oxidative defence pathway. Cell Death Dis. 2017;8:e2531 pubmed publisher
  • western blot; human; 1:1000; loading ...; fig 7h
Kicinska A, Augustynek B, Kulawiak B, Jarmuszkiewicz W, Szewczyk A, Bednarczyk P. A large-conductance calcium-regulated K+ channel in human dermal fibroblast mitochondria. Biochem J. 2016;473:4457-4471 pubmed
  • western blot; human; 1:1000; loading ...; fig 8f
Jones R, Robinson T, Liu J, Shrestha M, Voisin V, Ju Y, et al. RB1 deficiency in triple-negative breast cancer induces mitochondrial protein translation. J Clin Invest. 2016;126:3739-3757 pubmed publisher
  • western blot; human; loading ...; fig 6a
Rohlenova K, Sachaphibulkij K, Stursa J, Bezawork Geleta A, Blecha J, Endaya B, et al. Selective Disruption of Respiratory Supercomplexes as a New Strategy to Suppress Her2high Breast Cancer. Antioxid Redox Signal. 2017;26:84-103 pubmed publisher
  • western blot; human; loading ...; fig 2b
Cheng M, Liu L, Lao Y, Liao W, Liao M, Luo X, et al. MicroRNA-181a suppresses parkin-mediated mitophagy and sensitizes neuroblastoma cells to mitochondrial uncoupler-induced apoptosis. Oncotarget. 2016;7:42274-42287 pubmed publisher
  • immunocytochemistry; mouse; 1:300; fig 6
Beck S, Guo L, Phensy A, Tian J, Wang L, Tandon N, et al. Deregulation of mitochondrial F1FO-ATP synthase via OSCP in Alzheimer's disease. Nat Commun. 2016;7:11483 pubmed publisher
  • western blot; mouse; 1:1000; fig 2
Chen Y, Pandiri I, Joe Y, Kim H, Kim S, Park J, et al. Synergistic Effects of Cilostazol and Probucol on ER Stress-Induced Hepatic Steatosis via Heme Oxygenase-1-Dependent Activation of Mitochondrial Biogenesis. Oxid Med Cell Longev. 2016;2016:3949813 pubmed publisher
  • western blot; mouse; fig 5
Liu D, Bordicchia M, Zhang C, Fang H, Wei W, Li J, et al. Activation of mTORC1 is essential for ?-adrenergic stimulation of adipose browning. J Clin Invest. 2016;126:1704-16 pubmed publisher
  • western blot; mouse; fig 7
Thornton T, Delgado P, Chen L, Salas B, Krementsov D, Fernández M, et al. Inactivation of nuclear GSK3β by Ser(389) phosphorylation promotes lymphocyte fitness during DNA double-strand break response. Nat Commun. 2016;7:10553 pubmed publisher
  • western blot; human; 1:100; fig 3
Mukherjee R, Chakrabarti O. Ubiquitin-mediated regulation of the E3 ligase GP78 by MGRN1 in trans affects mitochondrial homeostasis. J Cell Sci. 2016;129:757-73 pubmed publisher
Machado A, Rodríguez Expósito E, Lopez M, Hernandez M. Phylogenetic analysis of the genus Laparocerus, with comments on colonisation and diversification in Macaronesia (Coleoptera, Curculionidae, Entiminae). Zookeys. 2017;:1-77 pubmed publisher
Zampieri S, Mammucari C, Romanello V, Barberi L, Pietrangelo L, Fusella A, et al. Physical exercise in aging human skeletal muscle increases mitochondrial calcium uniporter expression levels and affects mitochondria dynamics. Physiol Rep. 2016;4: pubmed publisher
Weijer R, Clavier S, Zaal E, Pijls M, van Kooten R, Vermaas K, et al. Multi-OMIC profiling of survival and metabolic signaling networks in cells subjected to photodynamic therapy. Cell Mol Life Sci. 2017;74:1133-1151 pubmed publisher
Nishikawa S, Aoyama H, Kamiya M, Higuchi J, Kato A, Soga M, et al. Artepillin C, a Typical Brazilian Propolis-Derived Component, Induces Brown-Like Adipocyte Formation in C3H10T1/2 Cells, Primary Inguinal White Adipose Tissue-Derived Adipocytes, and Mice. PLoS ONE. 2016;11:e0162512 pubmed publisher
Hada M, Subramanian C, Andrews P, Kwok R. Cytosolic Ku70 regulates Bax-mediated cell death. Tumour Biol. 2016;37:13903-13914 pubmed
Hsu P, Mo F. Matricellular protein CCN1 mediates doxorubicin-induced cardiomyopathy in mice. Oncotarget. 2016;7:36698-36710 pubmed publisher
Sin J, Andres A, Taylor D, Weston T, Hiraumi Y, Stotland A, et al. Mitophagy is required for mitochondrial biogenesis and myogenic differentiation of C2C12 myoblasts. Autophagy. 2016;12:369-80 pubmed publisher
product information
SKU :
4844S
Product-Name :
COX IV Antibody
Size :
100 ul
Price-(USD) :
235 USD
Species-x-Reactivity :
H, M, R, Mk, B
Applications :
Flow cytometry
Product-Category :
Metabolism
Shipping-Temp :
AMBIENT
Storage-Temp :
-20°C
Product-Type :
Polyclonal Antibody
MW :
17
Host :
Rabbit
Target :
COX IV
Primary-Protein :
COX4I1
Alt-Names :
COX IV-1,COX4,COX41,COX4I1,COXIV,Cytochrome c oxidase polypeptide IV,Cytochrome c oxidase subunit 4 isoform 1, mitochondrial,Cytochrome c oxidase subunit IV isoform 1,MGC72016
company information
Cell Signaling Technology
3 Trask Lane
Danvers, MA 01923
info@cellsignal.com
https://www.cellsignal.com
8776162355
headquarters: USA
Established in Beverly, MA in 1999, Cell Signaling Technology (CST) is a privately-owned company with over 400 employees worldwide. We are dedicated to providing innovative research tools that are used to help define mechanisms underlying cell function and disease. Since its inception, CST has become the world leader in the production of the highest quality activation-state and total protein antibodies utilized to expand knowledge of cell signaling pathways. Our mission is to deliver the world's highest quality research tools that accelerate progress in biological research and personalized medicine.