product summary
company name :
Cell Signaling Technology
product type :
antibody
product name :
PHD-2/Egln1 (D31E11) Rabbit mAb
catalog :
4835S
quantity :
100 ul
price :
235 USD
clonality :
monoclonal
host :
rabbit
reactivity :
human, mouse, rat
application :
western blot, immunoprecipitation
citations: 4
Published Application/Species/DilutionReference
  • western blot; mouse; 1:1000
Cheng S, Xing W, Pourteymoor S, Mohan S. Conditional disruption of the prolyl hydroxylase domain-containing protein 2 (Phd2) gene defines its key role in skeletal development. J Bone Miner Res. 2014;29:2276-86 pubmed publisher
  • western blot; mouse; fig 3a
Zheng X, Zhai B, Koivunen P, Shin S, Lu G, Liu J, et al. Prolyl hydroxylation by EglN2 destabilizes FOXO3a by blocking its interaction with the USP9x deubiquitinase. Genes Dev. 2014;28:1429-44 pubmed publisher
Tadakawa M, Takeda T, Li B, Tsuiji K, Yaegashi N. The anti-diabetic drug metformin inhibits vascular endothelial growth factor expression via the mammalian target of rapamycin complex 1/hypoxia-inducible factor-1α signaling pathway in ELT-3 cells. Mol Cell Endocrinol. 2015;399:1-8 pubmed publisher
Song D, Li L, Arsenault P, Tan Q, Bigham A, Heaton-Johnson K, et al. Defective Tibetan PHD2 binding to p23 links high altitude adaption to altered oxygen sensing. J Biol Chem. 2014;289:14656-65 pubmed publisher
product information
SKU :
4835S
Product-Name :
PHD-2/Egln1 (D31E11) Rabbit mAb
Size :
100 ul
Price-(USD) :
235 USD
Species-x-Reactivity :
H, M, R, Mk
Applications :
Immunoprecipitation
Product-Category :
Developmental Biology
Shipping-Temp :
AMBIENT
Storage-Temp :
-20°C
Product-Type :
Monoclonal Antibody
MW :
50
Host :
Rabbit
Target :
PHD-2 (Egln1)
Primary-Protein :
EGLN1
Alt-Names :
C1orf12,DKFZp761F179,ECYT3,EGLN1,Egl nine homolog 1,HIF prolyl hydroxylase 2,HIF-PH2,HIF-prolyl hydroxylase 2,HIFPH2,HPH-2,HPH2,Hypoxia-inducible factor prolyl hydroxylase 2,PHD2,Prolyl hydroxylase domain-containing protein 2,SM-20,SM20,ZMYND6,egl nine homolog 1 (C. elegans),egl nine-like protein 1,zinc finger MYND domain-containing protein 6
company information
Cell Signaling Technology
3 Trask Lane
Danvers, MA 01923
info@cellsignal.com
www.cellsignal.com
8776162355
headquarters: USA
Established in Beverly, MA in 1999, Cell Signaling Technology (CST) is a privately-owned company with over 400 employees worldwide. We are dedicated to providing innovative research tools that are used to help define mechanisms underlying cell function and disease. Since its inception, CST has become the world leader in the production of the highest quality activation-state and total protein antibodies utilized to expand knowledge of cell signaling pathways. Our mission is to deliver the world's highest quality research tools that accelerate progress in biological research and personalized medicine.