Akt (pan) (40D4) Mouse mAb (Biotinylated) | Cell Signaling Technology 4821 product information

product summary

company name :

Cell Signaling Technology

product type :

antibody

product name :

Akt (pan) (40D4) Mouse mAb (Biotinylated)

catalog :

4821

clonality :

monoclonal

host :

mouse

conjugate :

biotin

clone name :

40D4

reactivity :

human, mouse

application :

western blot, immunoprecipitation, flow cytometry

more info or order :

Cell Signaling Technology product webpage

citations: 12

Published Application/Species/Sample/Dilution	Reference
western blot; mouse; 1:1000; fig 5 western blot; human; 1:1000; fig 3	Mendonsa A, Chalfant M, Gorden L, VanSaun M. Modulation of the leptin receptor mediates tumor growth and migration of pancreatic cancer cells. PLoS ONE. 2015;10:e0126686 pubmed publisher
	Micel L, Tentler J, Tan A, Selby H, Brunkow K, Robertson K, et al. Antitumor activity of the MEK inhibitor TAK-733 against melanoma cell lines and patient-derived tumor explants. Mol Cancer Ther. 2015;14:317-25 pubmed publisher
	Schrader A, Popal W, Lilienthal N, Crispatzu G, Mayer P, Jones D, et al. AKT-pathway inhibition in chronic lymphocytic leukemia reveals response relationships defined by TCL1. Curr Cancer Drug Targets. 2014;14:700-12 pubmed
	Veeriah S, Leboucher P, de Naurois J, Jethwa N, Nye E, Bunting T, et al. High-throughput time-resolved FRET reveals Akt/PKB activation as a poor prognostic marker in breast cancer. Cancer Res. 2014;74:4983-95 pubmed publisher
	Shivaswamy V, Bennett R, Clure C, Ottemann B, Davis J, Larsen J, et al. Tacrolimus and sirolimus have distinct effects on insulin signaling in male and female rats. Transl Res. 2014;163:221-31 pubmed publisher
	Du Y, Teng X, Wang N, Zhang X, Chen J, Ding P, et al. NF-?B and enhancer-binding CREB protein scaffolded by CREB-binding protein (CBP)/p300 proteins regulate CD59 protein expression to protect cells from complement attack. J Biol Chem. 2014;289:2711-24 pubmed publisher
	Li J, Huang J, Jeong J, Park S, Wei R, Peng J, et al. Selective TBK1/IKKi dual inhibitors with anticancer potency. Int J Cancer. 2014;134:1972-80 pubmed publisher
	Liu C, Leclair P, Yap S, Lim C. The membrane-proximal KXGFFKR motif of ?-integrin mediates chemoresistance. Mol Cell Biol. 2013;33:4334-45 pubmed publisher
	Aftimos P, Wiedig M, Langouo Fontsa M, Awada A, Ghanem G, Journe F. Sequential use of protein kinase inhibitors potentiates their toxicity to melanoma cells: a rationale to combine targeted drugs based on protein expression inhibition profiles. Int J Oncol. 2013;43:919-26 pubmed publisher
	Keysar S, Astling D, Anderson R, Vogler B, Bowles D, Morton J, et al. A patient tumor transplant model of squamous cell cancer identifies PI3K inhibitors as candidate therapeutics in defined molecular bins. Mol Oncol. 2013;7:776-90 pubmed publisher
	RODRIGUEZ M, Potter D. CYP1A1 regulates breast cancer proliferation and survival. Mol Cancer Res. 2013;11:780-92 pubmed publisher
	Strittmatter F, Walther S, Roosen A, Rutz B, Schlenker B, Limmer S, et al. Activation of protein kinase B/Akt by alpha1-adrenoceptors in the human prostate. Life Sci. 2012;90:446-53 pubmed publisher

product information

SKU :

4821S

Product-Name :

Akt (pan) (40D4) Mouse mAb (Biotinylated)

Size :

100 ul

Price-(USD) :

291 USD

Species-x-Reactivity :

H, M, R, Mk

Applications :

Flow cytometry

Product-Category :

PI3K / Akt Signaling

Shipping-Temp :

AMBIENT

Storage-Temp :

-20°C

Product-Type :

Monoclonal Antibody

MW :

Host :

Mouse

Target :

Akt1/Akt2/Akt3

more info or order :

Cell Signaling Technology product webpage