product summary
company name :
Cell Signaling Technology
product type :
antibody
product name :
USP18 (D4E7) Rabbit mAb
catalog :
4813
clonality :
monoclonal
host :
domestic rabbit
conjugate :
nonconjugated
clone name :
D4E7
reactivity :
Betainfluenzavirus, human, mouse, Human immunodeficiency virus 1
application :
western blot, immunohistochemistry, immunoprecipitation
more info or order :
Cell Signaling Technology product webpage
citations: 6
Published Application/Species/Sample/DilutionReference
  • western blot; human; 1:1000; loading ...; fig 1s3b
Pan T, Song Z, Wu L, Liu G, Ma X, Peng Z, et al. USP49 potently stabilizes APOBEC3G protein by removing ubiquitin and inhibits HIV-1 replication. elife. 2019;8: pubmed publisher
  • western blot; Human immunodeficiency virus 1; loading ...; fig 2c
Taylor J, Cash M, Santostefano K, Nakanishi M, Terada N, Wallet M. CRISPR/Cas9 knockout of USP18 enhances type I IFN responsiveness and restricts HIV-1 infection in macrophages. J Leukoc Biol. 2018;: pubmed publisher
  • western blot; mouse; loading ...; fig 2a
  • western blot; human; loading ...; fig 1c
Mustachio L, Kawakami M, Lu Y, Rodriguez Canales J, Mino B, Behrens C, et al. The ISG15-specific protease USP18 regulates stability of PTEN. Oncotarget. 2017;8:3-14 pubmed publisher
  • western blot; Betainfluenzavirus; 1:1000; loading ...; fig s1c
Zhao C, Sridharan H, Chen R, Baker D, Wang S, Krug R. Influenza B virus non-structural protein 1 counteracts ISG15 antiviral activity by sequestering ISGylated viral proteins. Nat Commun. 2016;7:12754 pubmed publisher
  • immunoprecipitation; human; 1:250; fig 5
  • western blot; human; 1:5000; fig 5
Speer S, Li Z, Buta S, Payelle Brogard B, Qian L, Vigant F, et al. ISG15 deficiency and increased viral resistance in humans but not mice. Nat Commun. 2016;7:11496 pubmed publisher
  • immunohistochemistry; human; fig 5
  • western blot; mouse
Chinyengetere F, Sekula D, Lu Y, Giustini A, Sanglikar A, Kawakami M, et al. Mice null for the deubiquitinase USP18 spontaneously develop leiomyosarcomas. BMC Cancer. 2015;15:886 pubmed publisher
product information
SKU :
4813S
Product-Name :
USP18 (D4E7) Rabbit mAb
Size :
100 ul
Price-(USD) :
235 USD
Species-x-Reactivity :
H
Applications :
Immunoprecipitation
Product-Category :
Ubiquitin and Ubiquitin-like proteins
Shipping-Temp :
AMBIENT
Storage-Temp :
-20°C
Product-Type :
Monoclonal Antibody
MW :
34, 39
Host :
Rabbit
Target :
USP18
Primary-Protein :
USP18
Alt-Names :
43 kDa ISG15-specific protease,ISG15-specific-processing protease,ISG43,UBP18,UBP43,USP18,Ubl carboxyl-terminal hydrolase 18,Ubl thioesterase 18,hUBP43,ubiquitin specific peptidase 18,ubiquitin specific protease 18
more info or order :
Cell Signaling Technology product webpage
company information
Cell Signaling Technology
3 Trask Lane
Danvers, MA 01923
info@cellsignal.com
https://www.cellsignal.com
8776162355
headquarters: USA
Established in Beverly, MA in 1999, Cell Signaling Technology (CST) is a privately-owned company with over 400 employees worldwide. We are dedicated to providing innovative research tools that are used to help define mechanisms underlying cell function and disease. Since its inception, CST has become the world leader in the production of the highest quality activation-state and total protein antibodies utilized to expand knowledge of cell signaling pathways. Our mission is to deliver the world's highest quality research tools that accelerate progress in biological research and personalized medicine.