| Published Application/Species/Sample/Dilution | Reference |
|---|
- western blot; human; loading ...; fig 3b
| Gao C, Deng J, Zhang H, Li X, Gu S, Zheng M, et al. HSPA13 facilitates NF-κB-mediated transcription and attenuates cell death responses in TNFα signaling. Sci Adv. 2021;7:eabh1756 pubmed publisher |
- western blot; human; 1:500; fig 4b
| Nadeem L, Balendran R, Dorogin A, Mesiano S, Shynlova O, Lye S. Pro-inflammatory signals induce 20α-HSD expression in myometrial cells: A key mechanism for local progesterone withdrawal. J Cell Mol Med. 2021;25:6773-6785 pubmed publisher |
- western blot; mouse; 1:2000; loading ...; fig s2d
| Li L, Yang L, Yang F, Zhao X, Xue S, Gong F. Ginkgo biloba Extract 50 (GBE50) Ameliorates Insulin Resistance, Hepatic Steatosis and Liver Injury in High Fat Diet-Fed Mice. J Inflamm Res. 2021;14:1959-1971 pubmed publisher |
- western blot; mouse; loading ...; fig 3c
| Ye S, Su L, Shan P, Ye B, Wu S, Liang G, et al. LCZ696 Attenuated Doxorubicin-Induced Chronic Cardiomyopathy Through the TLR2-MyD88 Complex Formation. Front Cell Dev Biol. 2021;9:654051 pubmed publisher |
- western blot; rat; 1:1000; loading ...; fig 6a
| Xu H, Wang Y, Luo Y. OTULIN is a new target of EA treatment in the alleviation of brain injury and glial cell activation via suppression of the NF-κB signalling pathway in acute ischaemic stroke rats. Mol Med. 2021;27:37 pubmed publisher |
- western blot; mouse; fig 2a
| Watahiki A, Hoshikawa S, Chiba M, Egusa H, Fukumoto S, Inuzuka H. Deficiency of Lipin2 Results in Enhanced NF-κB Signaling and Osteoclast Formation in RAW-D Murine Macrophages. Int J Mol Sci. 2021;22: pubmed publisher |
- western blot; mouse; 1:1000; loading ...; fig 6g
| Yin S, Li L, Tao Y, Yu J, Wei S, Liu M, et al. The Inhibitory Effect of Artesunate on Excessive Endoplasmic Reticulum Stress Alleviates Experimental Colitis in Mice. Front Pharmacol. 2021;12:629798 pubmed publisher |
- western blot; human; 1:1000; loading ...; fig s1b
| Takenaga K, Ochiya T, Endo H. Inhibition of the invasion and metastasis of mammary carcinoma cells by NBD peptide targeting S100A4 via the suppression of the Sp1/MMP‑14 axis. Int J Oncol. 2021;58:397-408 pubmed publisher |
- western blot; mouse; loading ...; fig 3f
| Yu Z, Li X, Yang M, Huang J, Fang Q, Jia J, et al. TRIM41 is required to innate antiviral response by polyubiquitinating BCL10 and recruiting NEMO. Signal Transduct Target Ther. 2021;6:90 pubmed publisher |
- western blot; mouse; 1:1000; loading ...; fig 5b
| Zhang Y, Liu J, Wang X, Zhang J, Xie C. Extracellular vesicle-encapsulated microRNA-23a from dorsal root ganglia neurons binds to A20 and promotes inflammatory macrophage polarization following peripheral nerve injury. Aging (Albany NY). 2021;13:6752-6764 pubmed publisher |
- western blot; mouse; 1:500; loading ...; fig 8
| Zallocchi M, Hati S, Xu Z, HAUSMAN W, Liu H, He D, et al. Characterization of quinoxaline derivatives for protection against iatrogenically induced hearing loss. JCI Insight. 2021;6: pubmed publisher |
- western blot; mouse; 1:1000; loading ...; fig 5a
| Kusakabe J, Hata K, Miyauchi H, Tajima T, Wang Y, Tamaki I, et al. Complement-5 Inhibition Deters Progression of Fulminant Hepatitis to Acute Liver Failure in Murine Models. Cell Mol Gastroenterol Hepatol. 2021;11:1351-1367 pubmed publisher |
- western blot; mouse; 1:1000; loading ...; fig 1j
| Stojakovic A, Trushin S, Sheu A, Khalili L, Chang S, Li X, et al. Partial inhibition of mitochondrial complex I ameliorates Alzheimer's disease pathology and cognition in APP/PS1 female mice. Commun Biol. 2021;4:61 pubmed publisher |
- western blot; human; fig 2b
| Nakayama A, Albarrán Juárez J, Liang G, Roquid K, Iring A, Tonack S, et al. Disturbed flow-induced Gs-mediated signaling protects against endothelial inflammation and atherosclerosis. JCI Insight. 2020;5: pubmed publisher |
- western blot; human; 1:500; loading ...; fig 4s4a, 6s3b
| Bogucka K, Pompaiah M, Marini F, Binder H, Harms G, Kaulich M, et al. ERK3/MAPK6 controls IL-8 production and chemotaxis. elife. 2020;9: pubmed publisher |
- western blot; mouse; loading ...; fig 2b
| Wang P, Qi X, Xu G, Liu J, Guo J, Li X, et al. CCL28 promotes locomotor recovery after spinal cord injury via recruiting regulatory T cells. Aging (Albany NY). 2019;11:7402-7415 pubmed publisher |
- western blot; human; loading ...; fig 4a
| Xu G, Xia Z, Deng F, Liu L, Wang Q, Yu Y, et al. Inducible LGALS3BP/90K activates antiviral innate immune responses by targeting TRAF6 and TRAF3 complex. PLoS Pathog. 2019;15:e1008002 pubmed publisher |
- western blot; human; loading ...; fig 2f
| Xia Z, Xu G, Nie L, Liu L, Peng N, He Q, et al. NAC1 Potentiates Cellular Antiviral Signaling by Bridging MAVS and TBK1. J Immunol. 2019;: pubmed publisher |
- western blot; human; loading ...; fig s4a
| Gu C, Wang L, Zurawski S, Oh S. Signaling Cascade through DC-ASGPR Induces Transcriptionally Active CREB for IL-10 Induction and Immune Regulation. J Immunol. 2019;: pubmed publisher |
- western blot; mouse; 1:1000; loading ...; fig 4a
| Herb M, Gluschko A, Wiegmann K, Farid A, Wolf A, Utermöhlen O, et al. Mitochondrial reactive oxygen species enable proinflammatory signaling through disulfide linkage of NEMO. Sci Signal. 2019;12: pubmed publisher |
- western blot; mouse; 1:1000; loading ...; fig 6c
| Bartholomew T, Kidd T, Sá Pessoa J, Conde Alvarez R, Bengoechea J. 2-Hydroxylation of Acinetobacter baumannii Lipid A Contributes to Virulence. Infect Immun. 2019;87: pubmed publisher |
- western blot; mouse; 1:1000; loading ...; fig 3g
| Zhang C, Jiang M, Zhou H, Liu W, Wang C, Kang Z, et al. TLR-stimulated IRAKM activates caspase-8 inflammasome in microglia and promotes neuroinflammation. J Clin Invest. 2018;128:5399-5412 pubmed publisher |
- western blot; mouse; loading ...; fig 6a
| Yin J, Wang Y, Chang J, Li B, Zhang J, Liu Y, et al. Apelin inhibited epithelial-mesenchymal transition of podocytes in diabetic mice through downregulating immunoproteasome subunits β5i. Cell Death Dis. 2018;9:1031 pubmed publisher |
- western blot; mouse; 1:1000
| Sun J, Wang Z, Wang X. Suppression of LRRC19 promotes cutaneous wound healing in pressure ulcers in mice. Organogenesis. 2018;14:13-24 pubmed publisher |
- western blot; human; loading ...; fig 3
| Yurchenko M, Skjesol A, Ryan L, Richard G, Kandasamy R, Wang N, et al. SLAMF1 is required for TLR4-mediated TRAM-TRIF-dependent signaling in human macrophages. J Cell Biol. 2018;217:1411-1429 pubmed publisher |
- western blot; human; 1:1000; loading ...; fig 8b
| Lu Y, Kim N, Jiang Y, Zhang H, Zheng D, Zhu F, et al. Cambogin suppresses dextran sulphate sodium-induced colitis by enhancing Treg cell stability and function. Br J Pharmacol. 2018;175:1085-1099 pubmed publisher |
- western blot; mouse; loading ...; fig s6e
| Purvis H, Clarke F, Jordan C, Blanco C, Cornish G, Dai X, et al. Protein tyrosine phosphatase PTPN22 regulates IL-1β dependent Th17 responses by modulating dectin-1 signaling in mice. Eur J Immunol. 2018;48:306-315 pubmed publisher |
- western blot; human; loading ...; fig 4d
| Penafuerte C, Feldhammer M, Mills J, Vinette V, Pike K, Hall A, et al. Downregulation of PTP1B and TC-PTP phosphatases potentiate dendritic cell-based immunotherapy through IL-12/IFN? signaling. Oncoimmunology. 2017;6:e1321185 pubmed publisher |
- immunoprecipitation; human; 1:100; loading ...; fig 4b
- western blot; human; 1:1000; loading ...; fig 4b
| Yue X, Zuo Y, Ke H, Luo J, Lou L, Qin W, et al. Identification of 4-arylidene curcumin analogues as novel proteasome inhibitors for potential anticancer agents targeting 19S regulatory particle associated deubiquitinase. Biochem Pharmacol. 2017;137:29-50 pubmed publisher |
- western blot; human; loading ...; fig 8b
| Xia Z, Xu G, Yang X, Peng N, Zuo Q, Zhu S, et al. Inducible TAP1 Negatively Regulates the Antiviral Innate Immune Response by Targeting the TAK1 Complex. J Immunol. 2017;198:3690-3704 pubmed publisher |
- western blot; human; loading ...; fig 3
| Bittner S, Knoll G, Ehrenschwender M. Death receptor 3 signaling enhances proliferation of human regulatory T cells. FEBS Lett. 2017;591:1187-1195 pubmed publisher |
- western blot; human; fig 1f
| Liu L, Jiang Y, Chahine A, Curtiss E, Steinle J. Epac1 agonist decreased inflammatory proteins in retinal endothelial cells, and loss of Epac1 increased inflammatory proteins in the retinal vasculature of mice. Mol Vis. 2017;23:1-7 pubmed |
- western blot; human; loading ...; fig 4b
| Mondello P, Derenzini E, Asgari Z, Philip J, Brea E, SESHAN V, et al. Dual inhibition of histone deacetylases and phosphoinositide 3-kinase enhances therapeutic activity against B cell lymphoma. Oncotarget. 2017;8:14017-14028 pubmed publisher |
- western blot; mouse; 1:1000; loading ...; fig s7b
| Wu M, Chen W, Lu Y, Zhu G, Hao L, Li Y. Gα13 negatively controls osteoclastogenesis through inhibition of the Akt-GSK3β-NFATc1 signalling pathway. Nat Commun. 2017;8:13700 pubmed publisher |
- western blot; mouse; loading ...; fig 4
| Luo Y, Duan H, Qian Y, Feng L, Wu Z, Wang F, et al. Macrophagic CD146 promotes foam cell formation and retention during atherosclerosis. Cell Res. 2017;27:352-372 pubmed publisher |
- western blot; human; 1:1000; loading ...; fig s4a,s4b
| Kim H, Kim M, Park Y, Park I, Kim T, Yang S, et al. Prostaglandin E2 Activates YAP and a Positive-Signaling Loop to Promote Colon Regeneration After Colitis but Also Carcinogenesis in Mice. Gastroenterology. 2017;152:616-630 pubmed publisher |
- western blot; mouse; loading ...; fig 1e
| Wang R, Zhang Y, Xu L, Lin Y, Yang X, Bai L, et al. Protein Inhibitor of Activated STAT3 Suppresses Oxidized LDL-induced Cell Responses during Atherosclerosis in Apolipoprotein E-deficient Mice. Sci Rep. 2016;6:36790 pubmed publisher |
- western blot; human; loading ...; fig 4a
| Lu W, Shi J, Zhang J, Lv Z, Guo F, Huang H, et al. CXCL12/CXCR4 Axis Regulates Aggrecanase Activation and Cartilage Degradation in a Post-Traumatic Osteoarthritis Rat Model. Int J Mol Sci. 2016;17: pubmed |
- western blot; mouse; loading ...; fig s5c, s6c
| Janowski A, Colegio O, Hornick E, McNiff J, Martin M, Badovinac V, et al. NLRC4 suppresses melanoma tumor progression independently of inflammasome activation. J Clin Invest. 2016;126:3917-3928 pubmed publisher |
- western blot; rat; 1:500; fig 3d
| Wu J, Hu G, Lu Y, Zheng J, Chen J, Wang X, et al. Palmitic acid aggravates inflammation of pancreatic acinar cells by enhancing unfolded protein response induced CCAAT-enhancer-binding protein ?-CCAAT-enhancer-binding protein ? activation. Int J Biochem Cell Biol. 2016;79:181-193 pubmed publisher |
- western blot; human; 1:1000; fig s15
| Nakazawa S, Oikawa D, Ishii R, Ayaki T, Takahashi H, Takeda H, et al. Linear ubiquitination is involved in the pathogenesis of optineurin-associated amyotrophic lateral sclerosis. Nat Commun. 2016;7:12547 pubmed publisher |
- western blot; mouse; 1:1000; fig 8
| Wang X, Shaw D, Hammond H, Sutterwala F, Rayamajhi M, Shirey K, et al. The Prostaglandin E2-EP3 Receptor Axis Regulates Anaplasma phagocytophilum-Mediated NLRC4 Inflammasome Activation. PLoS Pathog. 2016;12:e1005803 pubmed publisher |
- western blot; mouse; 1:1000; fig 5c
| Yan X, Cen Y, Wang Q. Mesenchymal stem cells alleviate experimental rheumatoid arthritis through microRNA-regulated I?B expression. Sci Rep. 2016;6:28915 pubmed publisher |
- western blot; mouse; 1:1000; fig 4
| Wang X, Fan F, Cao Q. Modified Pulsatilla decoction attenuates oxazolone-induced colitis in mice through suppression of inflammation and epithelial barrier disruption. Mol Med Rep. 2016;14:1173-9 pubmed publisher |
- western blot; mouse; fig 4
| Yang Y, Andersson P, Hosaka K, Zhang Y, Cao R, Iwamoto H, et al. The PDGF-BB-SOX7 axis-modulated IL-33 in pericytes and stromal cells promotes metastasis through tumour-associated macrophages. Nat Commun. 2016;7:11385 pubmed publisher |
- western blot; human; fig 5
| Zeng W, Liu Q, Chen Z, Wu X, Zhong Y, Wu J. Silencing of hERG1 Gene Inhibits Proliferation and Invasion, and Induces Apoptosis in Human Osteosarcoma Cells by Targeting the NF-?B Pathway. J Cancer. 2016;7:746-57 pubmed publisher |
- western blot; mouse; loading ...; fig 4a
| Yu Z, Chen T, Li X, Yang M, Tang S, Zhu X, et al. Lys29-linkage of ASK1 by Skp1-Cullin 1-Fbxo21 ubiquitin ligase complex is required for antiviral innate response. elife. 2016;5: pubmed publisher |
- western blot; human; loading ...; fig 6a
| Waguia Kontchou C, Tzivelekidis T, Gentle I, Hacker G. Infection of epithelial cells with Chlamydia trachomatis inhibits TNF-induced apoptosis at the level of receptor internalization while leaving non-apoptotic TNF-signalling intact. Cell Microbiol. 2016;18:1583-1595 pubmed publisher |
- western blot; human; loading ...; fig 2a
| Jiang S, Li X, Hess N, Guan Y, Tapping R. TLR10 Is a Negative Regulator of Both MyD88-Dependent and -Independent TLR Signaling. J Immunol. 2016;196:3834-41 pubmed publisher |
- western blot; mouse; 1:1000; loading ...; fig 5d
| Leus N, van der Wouden P, van den Bosch T, Hooghiemstra W, Ourailidou M, Kistemaker L, et al. HDAC 3-selective inhibitor RGFP966 demonstrates anti-inflammatory properties in RAW 264.7 macrophages and mouse precision-cut lung slices by attenuating NF-κB p65 transcriptional activity. Biochem Pharmacol. 2016;108:58-74 pubmed publisher |
- western blot; mouse; fig 5
| Ding X, Pan L, Wang Y, Xu Q. Baicalin exerts protective effects against lipopolysaccharide-induced acute lung injury by regulating the crosstalk between the CX3CL1-CX3CR1 axis and NF-κB pathway in CX3CL1-knockout mice. Int J Mol Med. 2016;37:703-15 pubmed publisher |
- western blot; mouse; fig 2b
| Liu H, Shi H, Huang F, Peterson K, Wu H, Lan Y, et al. Astragaloside IV inhibits microglia activation via glucocorticoid receptor mediated signaling pathway. Sci Rep. 2016;6:19137 pubmed publisher |
- western blot; mouse; 1:1000; fig 8
| Ogura Y, Hindi S, Sato S, Xiong G, Akira S, Kumar A. TAK1 modulates satellite stem cell homeostasis and skeletal muscle repair. Nat Commun. 2015;6:10123 pubmed publisher |
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| Niu F, Yao H, Zhang W, Sutliff R, Buch S. Tat 101-mediated enhancement of brain pericyte migration involves platelet-derived growth factor subunit B homodimer: implications for human immunodeficiency virus-associated neurocognitive disorders. J Neurosci. 2014;34:11812-25 pubmed publisher |
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| Leidner J, Voogdt C, Niedenthal R, Moller P, Marienfeld U, Marienfeld R. SUMOylation attenuates the transcriptional activity of the NF-?B subunit RelB. J Cell Biochem. 2014;115:1430-40 pubmed publisher |
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| Xu Z, Dong D, Chen X, Huang H, Wen S. MicroRNA-381 Negatively Regulates TLR4 Signaling in A549 Cells in Response to LPS Stimulation. Biomed Res Int. 2015;2015:849475 pubmed publisher |
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