product summary
company name :
Cell Signaling Technology
product type :
antibody
product name :
Clathrin Heavy Chain (D3C6) XP® Rabbit mAb
catalog :
4796
clonality :
monoclonal
host :
domestic rabbit
conjugate :
nonconjugated
clone name :
D3C6
reactivity :
human, mouse, rat
application :
western blot, immunohistochemistry, immunocytochemistry, immunoprecipitation
citations: 10
Published Application/Species/Sample/DilutionReference
  • western blot; mouse; loading ...; fig 3c
Wan Z, Zhao L, Lu F, Gao X, Dong Y, Zhao Y, et al. Mononuclear phagocyte system blockade improves therapeutic exosome delivery to the myocardium. Theranostics. 2020;10:218-230 pubmed publisher
  • immunocytochemistry; human; 1:400; fig 4j
Genet G, Boyé K, Mathivet T, Ola R, Zhang F, Dubrac A, et al. Endophilin-A2 dependent VEGFR2 endocytosis promotes sprouting angiogenesis. Nat Commun. 2019;10:2350 pubmed publisher
  • western blot; human; 1:1000; loading ...; fig 4c
Agajanian M, Walker M, Axtman A, Ruela de Sousa R, Serafin D, Rabinowitz A, et al. WNT Activates the AAK1 Kinase to Promote Clathrin-Mediated Endocytosis of LRP6 and Establish a Negative Feedback Loop. Cell Rep. 2019;26:79-93.e8 pubmed publisher
  • immunocytochemistry; human; loading ...; fig 4a
Swain S, Roe M, Sebrell T, Sidar B, Dankoff J, VanAusdol R, et al. CD103 (αE Integrin) Undergoes Endosomal Trafficking in Human Dendritic Cells, but Does Not Mediate Epithelial Adhesion. Front Immunol. 2018;9:2989 pubmed publisher
  • immunocytochemistry; human; loading ...; fig 4a
Merrill N, Schipper J, Karnes J, Kauffman A, Martin K, Mackeigan J. PI3K-C2? knockdown decreases autophagy and maturation of endocytic vesicles. PLoS ONE. 2017;12:e0184909 pubmed publisher
  • immunocytochemistry; mouse; fig 2
Boothe T, Lim G, Cen H, Skovsø S, Piske M, Li S, et al. Inter-domain tagging implicates caveolin-1 in insulin receptor trafficking and Erk signaling bias in pancreatic beta-cells. Mol Metab. 2016;5:366-378 pubmed publisher
  • immunohistochemistry; mouse; 1:100; fig 7
Grego Bessa J, Bloomekatz J, Castel P, Omelchenko T, Baselga J, Anderson K. The tumor suppressor PTEN and the PDK1 kinase regulate formation of the columnar neural epithelium. elife. 2016;5:e12034 pubmed publisher
Nakamura K, Yamanouchi K, Nishihara M. Secreted protein acidic and rich in cysteine internalization and its age-related alterations in skeletal muscle progenitor cells. Aging Cell. 2014;13:175-84 pubmed publisher
Song N, Ding Y, Zhuo W, He T, Fu Z, Chen Y, et al. The nuclear translocation of endostatin is mediated by its receptor nucleolin in endothelial cells. Angiogenesis. 2012;15:697-711 pubmed publisher
Béliveau F, Brulé C, Desilets A, Zimmerman B, Laporte S, Lavoie C, et al. Essential role of endocytosis of the type II transmembrane serine protease TMPRSS6 in regulating its functionality. J Biol Chem. 2011;286:29035-43 pubmed publisher
product information
SKU :
4796S
Product-Name :
Clathrin Heavy Chain (D3C6) XP® Rabbit mAb
Size :
100 ul
Price-(USD) :
260 USD
Species-x-Reactivity :
H, M, R, Mk, (Pg)
Applications :
Immunofluorescence (Immunocytochemistry)
Product-Category :
Protein Folding and Trafficking
Shipping-Temp :
AMBIENT
Storage-Temp :
-20°C
Product-Type :
Monoclonal Antibody
MW :
190
Host :
Rabbit
Target :
CLTC
Primary-Protein :
CLTC
Alt-Names :
CHC,CHC17,CLH-17,CLH1,CLH17,CLTC,CLTCL2,Clathrin heavy chain 1,Clathrin heavy chain on chromosome 17,Hc,KIAA0034,clathrin, heavy chain (Hc),clathrin, heavy polypeptide (Hc),clathrin, heavy polypeptide-like 2
company information
Cell Signaling Technology
3 Trask Lane
Danvers, MA 01923
info@cellsignal.com
https://www.cellsignal.com
8776162355
headquarters: USA
Established in Beverly, MA in 1999, Cell Signaling Technology (CST) is a privately-owned company with over 400 employees worldwide. We are dedicated to providing innovative research tools that are used to help define mechanisms underlying cell function and disease. Since its inception, CST has become the world leader in the production of the highest quality activation-state and total protein antibodies utilized to expand knowledge of cell signaling pathways. Our mission is to deliver the world's highest quality research tools that accelerate progress in biological research and personalized medicine.