product summary
company name :
Cell Signaling Technology
product type :
antibody
product name :
Caspase-8 (D35G2) Rabbit mAb
catalog :
4790S
quantity :
100 ul
price :
235 USD
clonality :
monoclonal
host :
rabbit
reactivity :
human, mouse, rat
application :
western blot, immunocytochemistry
citations: 10
Published Application/Species/DilutionReference
  • western blot; human; 1:1000; fig s15
Nakazawa S, Oikawa D, Ishii R, Ayaki T, Takahashi H, Takeda H, et al. Linear ubiquitination is involved in the pathogenesis of optineurin-associated amyotrophic lateral sclerosis. Nat Commun. 2016;7:12547 pubmed publisher
  • western blot; rat
  • immunocytochemistry; human
Zhang L, Wang H, Ding K, Xu J. FTY720 induces autophagy-related apoptosis and necroptosis in human glioblastoma cells. Toxicol Lett. 2015;236:43-59 pubmed publisher
  • western blot; human; fig 7
Oh Y, Yue P, Wang D, Tong J, Chen Z, Khuri F, et al. Suppression of death receptor 5 enhances cancer cell invasion and metastasis through activation of caspase-8/TRAF2-mediated signaling. Oncotarget. 2015;6:41324-38 pubmed publisher
  • western blot; mouse; fig 4c
Deutsch M, Graffeo C, Rokosh R, Pansari M, Ochi A, Levie E, et al. Divergent effects of RIP1 or RIP3 blockade in murine models of acute liver injury. Cell Death Dis. 2015;6:e1759 pubmed publisher
  • western blot; rat; 1:1000; fig 4
Liu K, Chuang S, Long C, Lee Y, Wang C, Lu M, et al. Ketamine-induced ulcerative cystitis and bladder apoptosis involve oxidative stress mediated by mitochondria and the endoplasmic reticulum. Am J Physiol Renal Physiol. 2015;309:F318-31 pubmed publisher
  • western blot; rat; 1:1000
Wang Y, Li Q, Wei X, Xu J, Chen Q, Song S, et al. Targeted knockout of TNF-α by injection of lentivirus-mediated siRNA into the subacromial bursa for the treatment of subacromial bursitis in rats. Mol Med Rep. 2015;12:4389-95 pubmed publisher
  • western blot; mouse; 1:1000
ErLin S, WenJie W, LiNing W, BingXin L, MingDe L, Yan S, et al. Musashi-1 maintains blood-testis barrier structure during spermatogenesis and regulates stress granule formation upon heat stress. Mol Biol Cell. 2015;26:1947-56 pubmed publisher
  • western blot; human; 1:1000
Chou C, Huang N, Jhuang S, Pan H, Peng N, Cheng J, et al. Ubiquitin-conjugating enzyme UBE2C is highly expressed in breast microcalcification lesions. PLoS ONE. 2014;9:e93934 pubmed publisher
  • western blot; human; 1:500
Ishikawa K, Saiki S, Furuya N, Yamada D, Imamichi Y, Li Y, et al. P150glued-associated disorders are caused by activation of intrinsic apoptotic pathway. PLoS ONE. 2014;9:e94645 pubmed publisher
Pritchard J, Gilbert L, Meacham C, Ricks J, Jiang H, Lauffenburger D, et al. Bcl-2 family genetic profiling reveals microenvironment-specific determinants of chemotherapeutic response. Cancer Res. 2011;71:5850-8 pubmed publisher
product information
SKU :
4790S
Product-Name :
Caspase-8 (D35G2) Rabbit mAb
Size :
100 ul
Price-(USD) :
235 USD
Species-x-Reactivity :
H, M, R, (Mk, Pg)
Applications :
Western blot
Product-Category :
Apoptosis
Shipping-Temp :
AMBIENT
Storage-Temp :
-20°C
Product-Type :
Monoclonal Antibody
MW :
10, 57
Host :
Rabbit
Target :
Casp8
Primary-Protein :
Casp8
Alt-Names :
ALPS2B,Apoptotic cysteine protease,Apoptotic protease Mch-5,CAP4,CASP-8,CASP8,Caspase-8,Caspase-8 subunit p10,Caspase-8 subunit p18,FADD-homologous ICE/ced-3-like protease,FADD-like ICE,FLICE,FLJ17672,ICE-like apoptotic protease 5,MACH,MACH-alpha-1/2/3 protein,MACH-beta-1/2/3/4 protein,MCH5,MGC78473,MORT1-associated ced-3 homolog,caspase 8, apoptosis-related cysteine peptidase,caspase 8, apoptosis-related cysteine protease
company information
Cell Signaling Technology
3 Trask Lane
Danvers, MA 01923
info@cellsignal.com
www.cellsignal.com
8776162355
headquarters: USA
Established in Beverly, MA in 1999, Cell Signaling Technology (CST) is a privately-owned company with over 400 employees worldwide. We are dedicated to providing innovative research tools that are used to help define mechanisms underlying cell function and disease. Since its inception, CST has become the world leader in the production of the highest quality activation-state and total protein antibodies utilized to expand knowledge of cell signaling pathways. Our mission is to deliver the world's highest quality research tools that accelerate progress in biological research and personalized medicine.