product summary
company name :
Cell Signaling Technology
product type :
antibody
product name :
Lamin A/C (4C11) Mouse mAb
catalog :
4777S
quantity :
100 ul
price :
235 USD
clonality :
monoclonal
host :
mouse
clone name :
4C11

The same clone is also sold as:
reactivity :
human, mouse, rat
application :
western blot, immunohistochemistry, immunocytochemistry, immunoprecipitation, flow cytometry, immunohistochemistry - frozen section
more info or order :
Cell Signaling Technology product webpage
citations: 16
Published Application/Species/DilutionReference
  • western blot; human
Duvall-Noelle N, Karwandyar A, Richmond A, Raman D. LASP-1: a nuclear hub for the UHRF1-DNMT1-G9a-Snail1 complex. Oncogene. 2016;35:1122-33 pubmed publisher
  • western blot; human; 1:2000; fig 5
Link S, Grund S, Diederichs S. Alternative splicing affects the subcellular localization of Drosha. Nucleic Acids Res. 2016;44:5330-43 pubmed publisher
  • western blot; human; 1:2000; fig 1
Deskin B, Lasky J, Zhuang Y, Shan B. Requirement of HDAC6 for activation of Notch1 by TGF-β1. Sci Rep. 2016;6:31086 pubmed publisher
  • western blot; mouse; fig 6h
Lee Y, Yun M, Kim H, Jeon B, Park B, Lee B, et al. Exogenous administration of DLK1 ameliorates hepatic steatosis and regulates gluconeogenesis via activation of AMPK. Int J Obes (Lond). 2016;40:356-65 pubmed publisher
  • immunocytochemistry; human; fig s3
Shukla S, Schmidt J, Goldfarb K, Cech T, Parker R. Inhibition of telomerase RNA decay rescues telomerase deficiency caused by dyskerin or PARN defects. Nat Struct Mol Biol. 2016;23:286-92 pubmed publisher
  • western blot; rat; fig 4
Raducu M, Fung E, Serres S, Infante P, Barberis A, Fischer R, et al. SCF (Fbxl17) ubiquitylation of Sufu regulates Hedgehog signaling and medulloblastoma development. EMBO J. 2016;35:1400-16 pubmed publisher
  • western blot; mouse
Chen C, Kim K, Lau L. The matricellular protein CCN1 suppresses hepatocarcinogenesis by inhibiting compensatory proliferation. Oncogene. 2016;35:1314-23 pubmed publisher
  • western blot; human; fig 1a
Hilton B, Li Z, Musich P, Wang H, Cartwright B, SERRANO M, et al. ATR Plays a Direct Antiapoptotic Role at Mitochondria, which Is Regulated by Prolyl Isomerase Pin1. Mol Cell. 2015;60:35-46 pubmed publisher
  • immunocytochemistry; human; 1:200
Taketa D, Nydam M, Langenbacher A, Rodriguez D, Sanders E, De Tomaso A. Molecular evolution and in vitro characterization of Botryllus histocompatibility factor. Immunogenetics. 2015;67:605-23 pubmed publisher
  • western blot; mouse; 1:5000; fig 4b
Shao D, Zhai P, Del Re D, Sciarretta S, Yabuta N, Nojima H, et al. A functional interaction between Hippo-YAP signalling and FoxO1 mediates the oxidative stress response. Nat Commun. 2014;5:3315 pubmed publisher
  • immunohistochemistry - frozen section; mouse; 1:20; fig 6
  • western blot; mouse; 1:20; fig 6
Wallace L, Roberts-Thompson L, Reichelt J. Deletion of K1/K10 does not impair epidermal stratification but affects desmosomal structure and nuclear integrity. J Cell Sci. 2012;125:1750-8 pubmed publisher
Furusawa T, Rochman M, Taher L, Dimitriadis E, Nagashima K, Anderson S, et al. Chromatin decompaction by the nucleosomal binding protein HMGN5 impairs nuclear sturdiness. Nat Commun. 2015;6:6138 pubmed publisher
Proietti S, Cucina A, Dobrowolny G, D'Anselmi F, Dinicola S, Masiello M, et al. Melatonin down-regulates MDM2 gene expression and enhances p53 acetylation in MCF-7 cells. J Pineal Res. 2014;57:120-9 pubmed publisher
Cubillos-Rojas M, Amair-Pinedo F, Peiró-Jordán R, Bartrons R, Ventura F, Rosa J. The E3 ubiquitin protein ligase HERC2 modulates the activity of tumor protein p53 by regulating its oligomerization. J Biol Chem. 2014;289:14782-95 pubmed publisher
Hashimoto T, Igarashi J, Hasan A, Ohmori K, Kohno M, Nagai Y, et al. Mifepristone promotes adiponectin production and improves insulin sensitivity in a mouse model of diet-induced-obesity. PLoS ONE. 2013;8:e79724 pubmed publisher
Buchan S, Al-Shamkhani A. Distinct motifs in the intracellular domain of human CD30 differentially activate canonical and alternative transcription factor NF-κB signaling. PLoS ONE. 2012;7:e45244 pubmed publisher
product information
SKU :
4777S
Product-Name :
Lamin A/C (4C11) Mouse mAb
Size :
100 ul
Price-(USD) :
235 USD
Species-x-Reactivity :
H, M, R, Mk
Applications :
Flow cytometry
Product-Category :
Apoptosis
Shipping-Temp :
AMBIENT
Storage-Temp :
-20°C
Product-Type :
Monoclonal Antibody
MW :
74 (Lamin A), 63 (Lamin C)
Host :
Mouse
Target :
Lamin A/C (full-length)
Primary-Protein :
lamin A/C
Alt-Names :
70 kDa lamin,CDCD1,CDDC,CMD1A,CMT2B1,EMD2,FPL,FPLD,HGPS,IDC,LDP1,LFP,LGMD1B,LMN1,LMNA,LMNC,Lamin-A/C,PRO1,Renal carcinoma antigen NY-REN-32,lamin A/C
more info or order :
Cell Signaling Technology product webpage
company information
Cell Signaling Technology
3 Trask Lane
Danvers, MA 01923
info@cellsignal.com
www.cellsignal.com
8776162355
headquarters: USA
Established in Beverly, MA in 1999, Cell Signaling Technology (CST) is a privately-owned company with over 400 employees worldwide. We are dedicated to providing innovative research tools that are used to help define mechanisms underlying cell function and disease. Since its inception, CST has become the world leader in the production of the highest quality activation-state and total protein antibodies utilized to expand knowledge of cell signaling pathways. Our mission is to deliver the world's highest quality research tools that accelerate progress in biological research and personalized medicine.