| Published Application/Species/Sample/Dilution | Reference |
|---|
- western blot; bovine; 1:700; fig 5
- western blot knockout validation; mouse; 1:700; fig 6
| Nayebosadri A, Ji J. Endothelial nuclear lamina is not required for glucocorticoid receptor nuclear import but does affect receptor-mediated transcription activation. Am J Physiol Cell Physiol. 2013;305:C309-22 pubmed publisher |
- western blot; rat; loading ...; fig 6f
| Sarker M, Lee J, Lee D, Chun K, Jun H. Attenuation of diabetic kidney injury in DPP4-deficient rats; role of GLP-1 on the suppression of AGE formation by inducing glyoxalase 1. Aging (Albany NY). 2020;12:593-610 pubmed publisher |
- western blot; human; loading ...; fig 7c
| Herring S, Moon H, Rawal P, Chhibber A, Zhao L. Brain clusterin protein isoforms and mitochondrial localization. elife. 2019;8: pubmed publisher |
- western blot; mouse; loading ...; fig s6a
| Liu Y, You Y, Lu Z, Yang J, Li P, Liu L, et al. N6-methyladenosine RNA modification-mediated cellular metabolism rewiring inhibits viral replication. Science. 2019;365:1171-1176 pubmed publisher |
- immunocytochemistry; human; loading ...; fig 1a
- western blot; human; loading ...; fig 4a
| Chatzifrangkeskou M, Pefani D, Eyres M, Vendrell I, Fischer R, Panková D, et al. RASSF1A is required for the maintenance of nuclear actin levels. EMBO J. 2019;38:e101168 pubmed publisher |
- western blot; human; fig 2d
| Gu Q, Yang X, Lv J, Zhang J, Xia B, Kim J, et al. AIBP-mediated cholesterol efflux instructs hematopoietic stem and progenitor cell fate. Science. 2019;363:1085-1088 pubmed publisher |
- western blot; mouse; fig s4i
| Shen Q, Zhang Q, Shi Y, Shi Q, Jiang Y, Gu Y, et al. Tet2 promotes pathogen infection-induced myelopoiesis through mRNA oxidation. Nature. 2018;554:123-127 pubmed publisher |
- immunocytochemistry; human; 1:50; loading ...; fig 4b
| Pleiner T, Bates M, Gorlich D. A toolbox of anti-mouse and anti-rabbit IgG secondary nanobodies. J Cell Biol. 2018;217:1143-1154 pubmed publisher |
- western blot; human; 1:2000; loading ...; fig s4c
- western blot; mouse; 1:2000; loading ...; fig s11
| Takaki T, Montagner M, Serres M, Le Berre M, Russell M, Collinson L, et al. Actomyosin drives cancer cell nuclear dysmorphia and threatens genome stability. Nat Commun. 2017;8:16013 pubmed publisher |
- immunocytochemistry; human; 1:100; loading ...; fig 3d
| Jones L, Goode L, Davila E, Brown A, McCarthy D, Sharma N, et al. Translational effects and coding potential of an upstream open reading frame associated with DOPA Responsive Dystonia. Biochim Biophys Acta Mol Basis Dis. 2017;1863:1171-1182 pubmed publisher |
- western blot; human; 1:1000; fig 5a
| Ju H, Ying H, Tian T, Ling J, Fu J, Lu Y, et al. Mutant Kras- and p16-regulated NOX4 activation overcomes metabolic checkpoints in development of pancreatic ductal adenocarcinoma. Nat Commun. 2017;8:14437 pubmed publisher |
- western blot; rat; loading ...; fig 5f
| Leow S, Chua S, Venkatachalam G, Shen L, Luo L, Clement M. Sub-lethal oxidative stress induces lysosome biogenesis via a lysosomal membrane permeabilization-cathepsin-caspase 3-transcription factor EB-dependent pathway. Oncotarget. 2017;8:16170-16189 pubmed publisher |
- western blot; human; fig 6a
| Wu L, Zhou B, Oshiro Rapley N, Li M, Paulo J, Webster C, et al. An Ancient, Unified Mechanism for Metformin Growth Inhibition in C. elegans and Cancer. Cell. 2016;167:1705-1718.e13 pubmed publisher |
- western blot; human; 1:2000; fig s15
| Nakazawa S, Oikawa D, Ishii R, Ayaki T, Takahashi H, Takeda H, et al. Linear ubiquitination is involved in the pathogenesis of optineurin-associated amyotrophic lateral sclerosis. Nat Commun. 2016;7:12547 pubmed publisher |
- western blot; human; 1:2000; fig 1
| Deskin B, Lasky J, Zhuang Y, Shan B. Requirement of HDAC6 for activation of Notch1 by TGF-?1. Sci Rep. 2016;6:31086 pubmed publisher |
- western blot; human; fig 2a
| François S, Sen N, Mitton B, Xiao X, Sakamoto K, Arvin A. Varicella-Zoster Virus Activates CREB, and Inhibition of the pCREB-p300/CBP Interaction Inhibits Viral Replication In Vitro and Skin Pathogenesis In Vivo. J Virol. 2016;90:8686-97 pubmed publisher |
- immunohistochemistry - paraffin section; mouse; loading ...; fig s1f
| Tillberg P, Chen F, Piatkevich K, Zhao Y, Yu C, English B, et al. Protein-retention expansion microscopy of cells and tissues labeled using standard fluorescent proteins and antibodies. Nat Biotechnol. 2016;34:987-92 pubmed publisher |
- western blot; human; 1:1000; fig 5e
| Zhang X, Cheng X, Yu L, Yang J, Calvo R, Patnaik S, et al. MCOLN1 is a ROS sensor in lysosomes that regulates autophagy. Nat Commun. 2016;7:12109 pubmed publisher |
| Raducu M, Fung E, Serres S, Infante P, Barberis A, Fischer R, et al. SCF (Fbxl17) ubiquitylation of Sufu regulates Hedgehog signaling and medulloblastoma development. EMBO J. 2016;35:1400-16 pubmed publisher |
- western blot; human; 1:2000; fig 5
| Link S, Grund S, Diederichs S. Alternative splicing affects the subcellular localization of Drosha. Nucleic Acids Res. 2016;44:5330-43 pubmed publisher |
- immunocytochemistry; human; fig s3
| Shukla S, Schmidt J, Goldfarb K, Cech T, Parker R. Inhibition of telomerase RNA decay rescues telomerase deficiency caused by dyskerin or PARN defects. Nat Struct Mol Biol. 2016;23:286-92 pubmed publisher |
- western blot; rat; 1:1000; loading ...; fig 3b
| Zámbó V, Tóth M, Schlachter K, Szelényi P, Sarnyai F, Lotz G, et al. Cytosolic localization of NADH cytochrome b₅ oxidoreductase (Ncb5or). FEBS Lett. 2016;590:661-71 pubmed publisher |
- immunocytochemistry; human; fig s3
| Ohsaki Y, Kawai T, Yoshikawa Y, Cheng J, Jokitalo E, Fujimoto T. PML isoform II plays a critical role in nuclear lipid droplet formation. J Cell Biol. 2016;212:29-38 pubmed publisher |
- immunocytochemistry; mouse; fig 4
| Chen Y, Tsou B, Hu S, Ma H, Liu X, Yen Y, et al. Autophagy induction causes a synthetic lethal sensitization to ribonucleotide reductase inhibition in breast cancer cells. Oncotarget. 2016;7:1984-99 pubmed publisher |
- western blot; human; fig 3
| Qin W, Li C, Zheng W, Guo Q, Zhang Y, Kang M, et al. Inhibition of autophagy promotes metastasis and glycolysis by inducing ROS in gastric cancer cells. Oncotarget. 2015;6:39839-54 pubmed publisher |
- immunohistochemistry - paraffin section; human; 1:5000; loading ...; fig 2C
| Fujino K, Motooka Y, Hassan W, Ali Abdalla M, Sato Y, Kudoh S, et al. Insulinoma-Associated Protein 1 Is a Crucial Regulator of Neuroendocrine Differentiation in Lung Cancer. Am J Pathol. 2015;185:3164-77 pubmed publisher |
- western blot; human; fig 1a
| Hilton B, Li Z, Musich P, Wang H, Cartwright B, SERRANO M, et al. ATR Plays a Direct Antiapoptotic Role at Mitochondria, which Is Regulated by Prolyl Isomerase Pin1. Mol Cell. 2015;60:35-46 pubmed publisher |
- immunocytochemistry; human; 1:200
| Taketa D, Nydam M, Langenbacher A, Rodriguez D, Sanders E, De Tomaso A. Molecular evolution and in vitro characterization of Botryllus histocompatibility factor. Immunogenetics. 2015;67:605-23 pubmed publisher |
- western blot; mouse; fig 6h
| Lee Y, Yun M, Kim H, Jeon B, Park B, Lee B, et al. Exogenous administration of DLK1 ameliorates hepatic steatosis and regulates gluconeogenesis via activation of AMPK. Int J Obes (Lond). 2016;40:356-65 pubmed publisher |
- western blot; mouse; 1:1000; fig 4
| Lim G, Albrecht T, Piske M, Sarai K, Lee J, Ramshaw H, et al. 14-3-3ζ coordinates adipogenesis of visceral fat. Nat Commun. 2015;6:7671 pubmed publisher |
- western blot; human; loading ...; fig 1d,7b
| McCloy R, Parker B, Rogers S, Chaudhuri R, Gayevskiy V, Hoffman N, et al. Global Phosphoproteomic Mapping of Early Mitotic Exit in Human Cells Identifies Novel Substrate Dephosphorylation Motifs. Mol Cell Proteomics. 2015;14:2194-212 pubmed publisher |
| Chen C, Kim K, Lau L. The matricellular protein CCN1 suppresses hepatocarcinogenesis by inhibiting compensatory proliferation. Oncogene. 2016;35:1314-23 pubmed publisher |
| Duvall Noelle N, Karwandyar A, Richmond A, Raman D. LASP-1: a nuclear hub for the UHRF1-DNMT1-G9a-Snail1 complex. Oncogene. 2016;35:1122-33 pubmed publisher |
- western blot; rat; 1:1000; fig 4
| Wong M, Nicholson C, Holloway A, Hardy D. Maternal nicotine exposure leads to impaired disulfide bond formation and augmented endoplasmic reticulum stress in the rat placenta. PLoS ONE. 2015;10:e0122295 pubmed publisher |
- immunocytochemistry; mouse; 1:200; loading ...; fig 6a
- western blot; mouse; 1:1000; loading ...; fig 1c
| Furusawa T, Rochman M, Taher L, Dimitriadis E, Nagashima K, Anderson S, et al. Chromatin decompaction by the nucleosomal binding protein HMGN5 impairs nuclear sturdiness. Nat Commun. 2015;6:6138 pubmed publisher |
- western blot; mouse; 1:5000; fig 4b
| Shao D, Zhai P, Del Re D, Sciarretta S, Yabuta N, Nojima H, et al. A functional interaction between Hippo-YAP signalling and FoxO1 mediates the oxidative stress response. Nat Commun. 2014;5:3315 pubmed publisher |
- immunohistochemistry - frozen section; mouse; 1:20; fig 6
- western blot; mouse; 1:20; fig 6
| Wallace L, Roberts Thompson L, Reichelt J. Deletion of K1/K10 does not impair epidermal stratification but affects desmosomal structure and nuclear integrity. J Cell Sci. 2012;125:1750-8 pubmed publisher |
| Chang J, Zhang W, Yeh H, Park M, Yao C, Shi Y, et al. An integrative model for alternative polyadenylation, IntMAP, delineates mTOR-modulated endoplasmic reticulum stress response. Nucleic Acids Res. 2018;46:5996-6008 pubmed publisher |
| Rockfield S, Flores I, Nanjundan M. Expression and function of nuclear receptor coactivator 4 isoforms in transformed endometriotic and malignant ovarian cells. Oncotarget. 2018;9:5344-5367 pubmed publisher |
| Hossen M, Yang W, Kim D, Aravinthan A, Kim J, Cho J. Thymoquinone: An IRAK1 inhibitor with in vivo and in vitro anti-inflammatory activities. Sci Rep. 2017;7:42995 pubmed publisher |
| Krall E, Wang B, Munoz D, Ilic N, Raghavan S, Niederst M, et al. KEAP1 loss modulates sensitivity to kinase targeted therapy in lung cancer. elife. 2017;6: pubmed publisher |
| Min J, Wright W, Shay J. Alternative lengthening of telomeres can be maintained by preferential elongation of lagging strands. Nucleic Acids Res. 2017;45:2615-2628 pubmed publisher |
| Hashimoto K, Tsuji Y. Arsenic-Induced Activation of the Homeodomain-Interacting Protein Kinase 2 (HIPK2) to cAMP-Response Element Binding Protein (CREB) Axis. J Mol Biol. 2017;429:64-78 pubmed publisher |
| Kurdi A, Bassil R, Olah M, Wu C, Xiao S, Taga M, et al. Tiam1/Rac1 complex controls Il17a transcription and autoimmunity. Nat Commun. 2016;7:13048 pubmed publisher |
| Abshire C, Carroll J, Dragoi A. FLASH protects ZEB1 from degradation and supports cancer cells' epithelial-to-mesenchymal transition. Oncogenesis. 2016;5:e254 pubmed publisher |
| Bermudez J, Webber H, Patel G, Liu X, Cheng Y, Clark A, et al. HDAC Inhibitor-Mediated Epigenetic Regulation of Glaucoma-Associated TGF?2 in the Trabecular Meshwork. Invest Ophthalmol Vis Sci. 2016;57:3698-707 pubmed publisher |
| Liu Y, Li T, Xu Y, Xu E, Zhou M, Wang B, et al. Effects of TLR4 gene silencing on the proliferation and apotosis of hepatocarcinoma HEPG2 cells. Oncol Lett. 2016;11:3054-3060 pubmed |
| Yu H, Li S, Tseng W, Tain Y, Chen C, Sheen J, et al. Early and late effects of prenatal corticosteroid treatment on the microRNA profiles of lung tissue in rats. Exp Ther Med. 2016;11:753-762 pubmed |
| Yang M, Yuan Z. A novel role of PRR14 in the regulation of skeletal myogenesis. Cell Death Dis. 2015;6:e1734 pubmed publisher |
| Tsai B, Jimenez J, Lim S, Fitzgerald K, Zhang M, Chuah C, et al. A novel Bcr-Abl-mTOR-eIF4A axis regulates IRES-mediated translation of LEF-1. Open Biol. 2014;4:140180 pubmed publisher |
| Proietti S, Cucina A, Dobrowolny G, D Anselmi F, Dinicola S, Masiello M, et al. Melatonin down-regulates MDM2 gene expression and enhances p53 acetylation in MCF-7 cells. J Pineal Res. 2014;57:120-9 pubmed publisher |
| Cubillos Rojas M, Amair Pinedo F, Peiró Jordán R, Bartrons R, Ventura F, Rosa J. The E3 ubiquitin protein ligase HERC2 modulates the activity of tumor protein p53 by regulating its oligomerization. J Biol Chem. 2014;289:14782-95 pubmed publisher |
| McCloy R, Rogers S, Caldon C, Lorca T, Castro A, Burgess A. Partial inhibition of Cdk1 in G 2 phase overrides the SAC and decouples mitotic events. Cell Cycle. 2014;13:1400-12 pubmed publisher |
| Uno M, Saitoh Y, Mochida K, Tsuruyama E, Kiyono T, Imoto I, et al. NF-?B inducing kinase, a central signaling component of the non-canonical pathway of NF-?B, contributes to ovarian cancer progression. PLoS ONE. 2014;9:e88347 pubmed publisher |
| Bachmann V, Bister K, Stefan E. Interplay of PKA and Rac: fine-tuning of Rac localization and signaling. Small Gtpases. 2013;4:247-51 pubmed publisher |
| Hashimoto T, Igarashi J, Hasan A, Ohmori K, Kohno M, Nagai Y, et al. Mifepristone promotes adiponectin production and improves insulin sensitivity in a mouse model of diet-induced-obesity. PLoS ONE. 2013;8:e79724 pubmed publisher |
| Prezma T, Shteinfer A, Admoni L, Raviv Z, Sela I, Levi I, et al. VDAC1-based peptides: novel pro-apoptotic agents and potential therapeutics for B-cell chronic lymphocytic leukemia. Cell Death Dis. 2013;4:e809 pubmed publisher |
| Nicholson J, Puche A, Guo Y, Weinreich D, Slater B, Bernstein S. PGJ(2) provides prolonged CNS stroke protection by reducing white matter edema. PLoS ONE. 2012;7:e50021 pubmed publisher |
| Buchan S, Al Shamkhani A. Distinct motifs in the intracellular domain of human CD30 differentially activate canonical and alternative transcription factor NF-?B signaling. PLoS ONE. 2012;7:e45244 pubmed publisher |
