Phospho-HER4/ErbB4 (Tyr1284) (21A9) Rabbit mAb | Cell Signaling Technology 4757 product information

product summary

company name :

Cell Signaling Technology

product type :

antibody

product name :

Phospho-HER4/ErbB4 (Tyr1284) (21A9) Rabbit mAb

catalog :

4757

clonality :

monoclonal

host :

rabbit

conjugate :

nonconjugated

antigen modification :

phosphorylated

clone name :

21A9

reactivity :

human, mouse, rat

application :

western blot

more info or order :

Cell Signaling Technology product webpage

citations: 11

Published Application/Species/Sample/Dilution	Reference
western blot; human; loading ...; fig 5e	Xue Z, Vis D, Bruna A, Sustic T, van Wageningen S, Batra A, et al. MAP3K1 and MAP2K4 mutations are associated with sensitivity to MEK inhibitors in multiple cancer models. Cell Res. 2018;28:719-729 pubmed publisher
western blot; human; 1:1000; loading ...; fig 3e	Kawata M, Morikawa S, Shiosaka S, Tamura H. Ablation of neuropsin-neuregulin 1 signaling imbalances ErbB4 inhibitory networks and disrupts hippocampal gamma oscillation. Transl Psychiatry. 2017;7:e1052 pubmed publisher
western blot; human; 1:1000; loading ...; fig 3	Kneissl J, Hartmann A, Pfarr N, Erlmeier F, Lorber T, Keller S, et al. Influence of the HER receptor ligand system on sensitivity to cetuximab and trastuzumab in gastric cancer cell lines. J Cancer Res Clin Oncol. 2017;143:573-600 pubmed publisher
western blot; mouse; fig 1	Wandinger S, Lahortiga I, Jacobs K, Klammer M, Jordan N, Elschenbroich S, et al. Quantitative Phosphoproteomics Analysis of ERBB3/ERBB4 Signaling. PLoS ONE. 2016;11:e0146100 pubmed publisher
western blot; human	Kurppa K, Denessiouk K, Johnson M, Elenius K. Activating ERBB4 mutations in non-small cell lung cancer. Oncogene. 2016;35:1283-91 pubmed publisher
western blot; human; 1:200; fig 1	Blancafort A, GirÃ³ Perafita A, Oliveras G, Palomeras S, Turrado C, Campuzano Ã, et al. Dual fatty acid synthase and HER2 signaling blockade shows marked antitumor activity against breast cancer models resistant to anti-HER2 drugs. PLoS ONE. 2015;10:e0131241 pubmed publisher
western blot; human; fig 5	Paatero I, Seagroves T, Vaparanta K, Han W, Jones F, Johnson R, et al. Hypoxia-inducible factor-1? induces ErbB4 signaling in the differentiating mammary gland. J Biol Chem. 2014;289:22459-69 pubmed publisher
western blot; human; fig 2	Brouxhon S, Kyrkanides S, Teng X, O Banion M, Clarke R, Byers S, et al. Soluble-E-cadherin activates HER and IAP family members in HER2+ and TNBC human breast cancers. Mol Carcinog. 2014;53:893-906 pubmed publisher
	Casanovas A, Salvany S, Lahoz V, Tarabal O, Piedrafita L, Sabater R, et al. Neuregulin 1-ErbB module in C-bouton synapses on somatic motor neurons: molecular compartmentation and response to peripheral nerve injury. Sci Rep. 2017;7:40155 pubmed publisher
	Wang G, Zhao X, Meng Z, Kern M, Dietrich A, Chen Z, et al. The brown fat-enriched secreted factor Nrg4 preserves metabolic homeostasis through attenuation of hepatic lipogenesis. Nat Med. 2014;20:1436-1443 pubmed publisher
	Weigelt B, Lo A, Park C, Gray J, Bissell M. HER2 signaling pathway activation and response of breast cancer cells to HER2-targeting agents is dependent strongly on the 3D microenvironment. Breast Cancer Res Treat. 2010;122:35-43 pubmed publisher

product information

SKU :

4757S

Product-Name :

Phospho-HER4/ErbB4 (Tyr1284) (21A9) Rabbit mAb

Size :

100 ul

Price-(USD) :

274 USD

Species-x-Reactivity :

H, (M, R)

Applications :

Western blot

Product-Category :

RTK

Shipping-Temp :

COLD

Storage-Temp :

-20°C

Product-Type :

Monoclonal Antibody

MW :

180

Host :

Rabbit

Target :

HER4/ErbB4 (Tyr1284) phosphate

Primary-Protein :

HER4

Alt-Names :

ERBB4,HER4,MGC138404,Proto-oncogene-like protein c-ErbB-4,Receptor tyrosine-protein kinase erbB-4,Tyrosine kinase-type cell surface receptor HER4,avian erythroblastic leukemia viral (v-erb-b2) oncogene homolog 4,p180erbB4,v-erb-a erythroblastic leukemia viral oncogene homolog 4 (avian)

more info or order :

Cell Signaling Technology product webpage