product summary
company name :
Cell Signaling Technology
product type :
antibody
product name :
HER3/ErbB3 (1B2E) Rabbit mAb
catalog :
4754S
quantity :
100 ul
price :
235 USD
clonality :
monoclonal
host :
rabbit
reactivity :
human, mouse, rat
application :
western blot, immunoprecipitation
more info or order :
Cell Signaling Technology product webpage
citations: 5
Published Application/Species/DilutionReference
  • western blot; human
Kugel C, Hartsough E, Davies M, Setiady Y, Aplin A. Function-blocking ERBB3 antibody inhibits the adaptive response to RAF inhibitor. Cancer Res. 2014;74:4122-32 pubmed publisher
  • western blot; human; fig 2
Brouxhon S, Kyrkanides S, Teng X, O'Banion M, Clarke R, Byers S, et al. Soluble-E-cadherin activates HER and IAP family members in HER2+ and TNBC human breast cancers. Mol Carcinog. 2014;53:893-906 pubmed publisher
Khalil H, Langdon S, Kankia I, Bown J, Deeni Y. NRF2 Regulates HER2 and HER3 Signaling Pathway to Modulate Sensitivity to Targeted Immunotherapies. Oxid Med Cell Longev. 2016;2016:4148791 pubmed publisher
Blair B, Wu X, Zahari M, Mohseni M, Cidado J, Wong H, et al. A phosphoproteomic screen demonstrates differential dependence on HER3 for MAP kinase pathway activation by distinct PIK3CA mutations. Proteomics. 2015;15:318-26 pubmed publisher
Weigelt B, Lo A, Park C, Gray J, Bissell M. HER2 signaling pathway activation and response of breast cancer cells to HER2-targeting agents is dependent strongly on the 3D microenvironment. Breast Cancer Res Treat. 2010;122:35-43 pubmed publisher
product information
SKU :
4754S
Product-Name :
HER3/ErbB3 (1B2E) Rabbit mAb
Size :
100 ul
Price-(USD) :
235 USD
Species-x-Reactivity :
H, (M, R)
Applications :
Immunoprecipitation
Product-Category :
RTK
Shipping-Temp :
COLD
Storage-Temp :
-20°C
Product-Type :
Monoclonal Antibody
MW :
185
Host :
Rabbit
Target :
HER3/ErbB3
Primary-Protein :
HER3
Alt-Names :
ERBB3,ErbB-3,HER3,LCCS2,MDA-BF-1,MGC88033,Proto-oncogene-like protein c-ErbB-3,Receptor tyrosine-protein kinase erbB-3,Tyrosine kinase-type cell surface receptor HER3,c-erbB-3,c-erbB3,erbB3-S,p180-ErbB3,p45-sErbB3,p85-sErbB3,v-erb-b2 avian erythroblastic leukemia viral oncogene homolog 3,v-erb-b2 erythroblastic leukemia viral oncogene homolog 3 (avian)
more info or order :
Cell Signaling Technology product webpage
company information
Cell Signaling Technology
3 Trask Lane
Danvers, MA 01923
info@cellsignal.com
www.cellsignal.com
8776162355
headquarters: USA
Established in Beverly, MA in 1999, Cell Signaling Technology (CST) is a privately-owned company with over 400 employees worldwide. We are dedicated to providing innovative research tools that are used to help define mechanisms underlying cell function and disease. Since its inception, CST has become the world leader in the production of the highest quality activation-state and total protein antibodies utilized to expand knowledge of cell signaling pathways. Our mission is to deliver the world's highest quality research tools that accelerate progress in biological research and personalized medicine.