product summary
company name :
Cell Signaling Technology
product type :
antibody
product name :
Pim-2 (D1D2) XP® Rabbit mAb
catalog :
4730
clonality :
monoclonal
host :
rabbit
conjugate :
nonconjugated
clone name :
D1D2
reactivity :
human
application :
western blot, immunohistochemistry, immunocytochemistry, immunoprecipitation
more info or order :
Cell Signaling Technology product webpage
citations: 7
Published Application/Species/Sample/DilutionReference
  • western blot; human; 1:1000; loading ...; fig 6c
Santio N, Salmela M, Arola H, Eerola S, Heino J, Rainio E, et al. The PIM1 kinase promotes prostate cancer cell migration and adhesion via multiple signalling pathways. Exp Cell Res. 2016;342:113-24 pubmed publisher
  • immunohistochemistry; human; fig 1f
  • western blot; human; loading ...; fig 1a
Green A, Maciel T, Hospital M, Yin C, Mazed F, Townsend E, et al. Pim kinases modulate resistance to FLT3 tyrosine kinase inhibitors in FLT3-ITD acute myeloid leukemia. Sci Adv. 2015;1:e1500221 pubmed publisher
  • western blot; human; fig s3
Moody S, Schinzel A, Singh S, Izzo F, Strickland M, Luo L, et al. PRKACA mediates resistance to HER2-targeted therapy in breast cancer cells and restores anti-apoptotic signaling. Oncogene. 2015;34:2061-71 pubmed publisher
  • western blot; human
Lu J, Zavorotinskaya T, Dai Y, Niu X, Castillo J, Sim J, et al. Pim2 is required for maintaining multiple myeloma cell growth through modulating TSC2 phosphorylation. Blood. 2013;122:1610-20 pubmed publisher
Tahvanainen J, Kylaniemi M, Kanduri K, Gupta B, Lähteenmäki H, Kallonen T, et al. Proviral integration site for Moloney murine leukemia virus (PIM) kinases promote human T helper 1 cell differentiation. J Biol Chem. 2013;288:3048-58 pubmed publisher
Gomez Abad C, Pisonero H, Blanco Aparicio C, Roncador G, Gonzalez Menchen A, Martinez Climent J, et al. PIM2 inhibition as a rational therapeutic approach in B-cell lymphoma. Blood. 2011;118:5517-27 pubmed publisher
Santio N, Vahakoski R, Rainio E, Sandholm J, Virtanen S, Prudhomme M, et al. Pim-selective inhibitor DHPCC-9 reveals Pim kinases as potent stimulators of cancer cell migration and invasion. Mol Cancer. 2010;9:279 pubmed publisher
product information
SKU :
4730S
Product-Name :
Pim-2 (D1D2) XP® Rabbit mAb
Size :
100 ul
Price-(USD) :
260 USD
Species-x-Reactivity :
H
Applications :
Immunofluorescence (Immunocytochemistry)
Product-Category :
Immunology and Inflammation
Shipping-Temp :
AMBIENT
Storage-Temp :
-20°C
Product-Type :
Monoclonal Antibody
MW :
40, 38, 34
Host :
Rabbit
Target :
Pim-2
Primary-Protein :
Pim2
Alt-Names :
PIM2,Pim-2h,Serine/threonine-protein kinase pim-2,pim-2 oncogene,proto-oncogene Pim-2 (serine threonine kinase),serine/threonine protein kinase pim-2
more info or order :
Cell Signaling Technology product webpage
company information
Cell Signaling Technology
3 Trask Lane
Danvers, MA 01923
info@cellsignal.com
www.cellsignal.com
8776162355
headquarters: USA
Established in Beverly, MA in 1999, Cell Signaling Technology (CST) is a privately-owned company with over 400 employees worldwide. We are dedicated to providing innovative research tools that are used to help define mechanisms underlying cell function and disease. Since its inception, CST has become the world leader in the production of the highest quality activation-state and total protein antibodies utilized to expand knowledge of cell signaling pathways. Our mission is to deliver the world's highest quality research tools that accelerate progress in biological research and personalized medicine.