product summary
company name :
Cell Signaling Technology
product type :
antibody
product name :
p48 Primase (8G10) Rat mAb
catalog :
4725
clonality :
monoclonal
host :
rat
conjugate :
nonconjugated
clone name :
8G10
reactivity :
human, mouse
application :
western blot
citations: 26
Reference
Wei Z, Yu D, Bi Y, Cao Y. A disintegrin and metalloprotease 17 promotes microglial cell survival via epidermal growth factor receptor signalling following spinal cord injury. Mol Med Rep. 2015;12:63-70 pubmed publisher
Lu K, Fang X, Feng L, Jiang Y, Zhou X, Liu X, et al. The STAT3 inhibitor WP1066 reverses the resistance of chronic lymphocytic leukemia cells to histone deacetylase inhibitors induced by interleukin-6. Cancer Lett. 2015;359:250-8 pubmed publisher
Wang S, Geng Z, Shi N, Li X, Wang Z. Dose-dependent effects of selenite (Se(4+)) on arsenite (As(3+))-induced apoptosis and differentiation in acute promyelocytic leukemia cells. Cell Death Dis. 2015;6:e1596 pubmed publisher
Guo L, Shen Y, Zhao X, Guo L, Yu Z, Wang D, et al. Curcumin combined with oxaliplatin effectively suppress colorectal carcinoma in vivo through inducing apoptosis. Phytother Res. 2015;29:357-65 pubmed publisher
Noack M, Richter Landsberg C. Activation of autophagy by rapamycin does not protect oligodendrocytes against protein aggregate formation and cell death induced by proteasomal inhibition. J Mol Neurosci. 2015;55:99-108 pubmed publisher
Idogawa M, Ohashi T, Sugisaka J, Sasaki Y, Suzuki H, Tokino T. Array-based genome-wide RNAi screening to identify shRNAs that enhance p53-related apoptosis in human cancer cells. Oncotarget. 2014;5:7540-8 pubmed
Wang S, Sun W, Zhao Y, McEachern D, Meaux I, Barrière C, et al. SAR405838: an optimized inhibitor of MDM2-p53 interaction that induces complete and durable tumor regression. Cancer Res. 2014;74:5855-65 pubmed publisher
Hirai S, Endo S, Saito R, Hirose M, Ueno T, Suzuki H, et al. Antitumor effects of a sirtuin inhibitor, tenovin-6, against gastric cancer cells via death receptor 5 up-regulation. PLoS ONE. 2014;9:e102831 pubmed publisher
Jaenisch N, Popp A, Guenther M, Schnabel J, Witte O, Frahm C. Pro-apoptotic function of GABA-related transcripts following stroke. Neurobiol Dis. 2014;70:237-44 pubmed publisher
GAO P, Tao N, Ma Q, Fan W, Ni C, Wang H, et al. DH332, a synthetic ?-carboline alkaloid, inhibits B cell lymphoma growth by activation of the caspase family. Asian Pac J Cancer Prev. 2014;15:3901-6 pubmed
Huang S, He R, Rong M, Dang Y, Chen G. Synergistic effect of MiR-146a mimic and cetuximab on hepatocellular carcinoma cells. Biomed Res Int. 2014;2014:384121 pubmed publisher
Mahajan I, Chen M, Muro I, Robertson J, Wright C, Bratton S. BH3-only protein BIM mediates heat shock-induced apoptosis. PLoS ONE. 2014;9:e84388 pubmed publisher
Li Z, Zhao C, Li Z, Zhao Y, Shan S, Shi T, et al. Reconstructed mung bean trypsin inhibitor targeting cell surface GRP78 induces apoptosis and inhibits tumor growth in colorectal cancer. Int J Biochem Cell Biol. 2014;47:68-75 pubmed publisher
Wang S, Huang J, Lyu H, Cai B, Yang X, Li F, et al. Therapeutic targeting of erbB3 with MM-121/SAR256212 enhances antitumor activity of paclitaxel against erbB2-overexpressing breast cancer. Breast Cancer Res. 2013;15:R101 pubmed
O Brien M, Carbin S, Morrison J, Smith T. Decreased myometrial p160 ROCK-1 expression in obese women at term pregnancy. Reprod Biol Endocrinol. 2013;11:79 pubmed publisher
Guerrero J, Alfaro I, Gomez F, Protter A, Bernales S. Enzalutamide, an androgen receptor signaling inhibitor, induces tumor regression in a mouse model of castration-resistant prostate cancer. Prostate. 2013;73:1291-305 pubmed publisher
Huang B, Ray P, Iwasaki K, Tsuji Y. Transcriptional regulation of the human ferritin gene by coordinated regulation of Nrf2 and protein arginine methyltransferases PRMT1 and PRMT4. FASEB J. 2013;27:3763-74 pubmed publisher
Li X, Chen T, Lin S, Zhao J, Chen P, Ba Q, et al. Valeriana jatamansi constituent IVHD-valtrate as a novel therapeutic agent to human ovarian cancer: in vitro and in vivo activities and mechanisms. Curr Cancer Drug Targets. 2013;13:472-83 pubmed
Fedorchenko O, Stiefelhagen M, Peer Zada A, Barthel R, Mayer P, Eckei L, et al. CD44 regulates the apoptotic response and promotes disease development in chronic lymphocytic leukemia. Blood. 2013;121:4126-36 pubmed publisher
Förster A, Falcone F, Gibbs B, Preussner L, Fiebig B, Altunok H, et al. Anti-Fas/CD95 and tumor necrosis factor-related apoptosis-inducing ligand (TRAIL) differentially regulate apoptosis in normal and neoplastic human basophils. Leuk Lymphoma. 2013;54:835-42 pubmed publisher
Wang L, Xiang S, Williams K, Dong H, Bai W, Nicosia S, et al. Depletion of HDAC6 enhances cisplatin-induced DNA damage and apoptosis in non-small cell lung cancer cells. PLoS ONE. 2012;7:e44265 pubmed publisher
Carnini A, Scott L, Ahrendt E, Proft J, Winkfein R, Kim S, et al. Cell line specific modulation of extracellular a?42 by Hsp40. PLoS ONE. 2012;7:e37755 pubmed publisher
Cheng F, Zhong X, Lu Y, Wang X, Song W, Guo S, et al. Refined Qingkailing Protects MCAO Mice from Endoplasmic Reticulum Stress-Induced Apoptosis with a Broad Time Window. Evid Based Complement Alternat Med. 2012;2012:567872 pubmed publisher
Venkataramani V, Thiele K, Behnes C, Wulf G, Thelen P, Opitz L, et al. Amyloid precursor protein is a biomarker for transformed human pluripotent stem cells. Am J Pathol. 2012;180:1636-52 pubmed publisher
Zhang J, Fang L, Zhu X, Qiao Y, Yu M, Wang L, et al. Ro52/SSA sensitizes cells to death receptor-induced apoptosis by down-regulating c-FLIP(L). Cell Biol Int. 2012;36:463-8 pubmed publisher
Deng X, Wang S, Deng A, Liu B, Edgerton S, Lind S, et al. Metformin targets Stat3 to inhibit cell growth and induce apoptosis in triple-negative breast cancers. Cell Cycle. 2012;11:367-76 pubmed publisher
product information
SKU :
4725S
Product-Name :
p48 Primase (8G10) Rat mAb
Size :
100 ul
Price-(USD) :
235 USD
Species-x-Reactivity :
H, M, R, Mk
Applications :
Western blot
Product-Category :
Cell Cycle / Checkpoint Control
Shipping-Temp :
AMBIENT
Storage-Temp :
-20°C
Product-Type :
Monoclonal Antibody
MW :
48
Host :
Rat
Target :
p48 Primase
Primary-Protein :
PRIM1
Alt-Names :
DNA primase 1,DNA primase 49 kDa subunit,DNA primase polypeptide 1,DNA primase small subunit,DNA primase subunit 48,MGC12308,PRI1,PRIM1,p49,primase p49 subunit,primase polypeptide 1, 49kDa,primase, DNA, polypeptide 1 (49kDa)
company information
Cell Signaling Technology
3 Trask Lane
Danvers, MA 01923
info@cellsignal.com
www.cellsignal.com
8776162355
headquarters: USA
Established in Beverly, MA in 1999, Cell Signaling Technology (CST) is a privately-owned company with over 400 employees worldwide. We are dedicated to providing innovative research tools that are used to help define mechanisms underlying cell function and disease. Since its inception, CST has become the world leader in the production of the highest quality activation-state and total protein antibodies utilized to expand knowledge of cell signaling pathways. Our mission is to deliver the world's highest quality research tools that accelerate progress in biological research and personalized medicine.