product summary
company name :
Cell Signaling Technology
product type :
antibody
product name :
TRAF2 (C192) Antibody
catalog :
4724
clonality :
polyclonal
host :
domestic rabbit
conjugate :
nonconjugated
reactivity :
human, mouse
application :
western blot, immunoprecipitation, western blot knockout validation
citations: 11
Published Application/Species/Sample/DilutionReference
  • western blot knockout validation; human; loading ...; fig 2a
Liu J, Hideshima T, Xing L, Wang S, Zhou W, Samur M, et al. ERK signaling mediates resistance to immunomodulatory drugs in the bone marrow microenvironment. Sci Adv. 2021;7: pubmed publisher
  • western blot knockout validation; mouse; 1:1000; loading ...; fig 3a
Hinte F, van Anken E, Tirosh B, Brune W. Repression of viral gene expression and replication by the unfolded protein response effector XBP1u. elife. 2020;9: pubmed publisher
  • western blot knockout validation; human; loading ...; fig 1h
Wang B, Jie Z, Joo D, Ordureau A, Liu P, Gan W, et al. TRAF2 and OTUD7B govern a ubiquitin-dependent switch that regulates mTORC2 signalling. Nature. 2017;545:365-369 pubmed publisher
  • western blot; human; 1:1000; loading ...; fig 1e
Guo G, Gao M, Gao X, Zhu B, Huang J, Luo K, et al. SARS-CoV-2 non-structural protein 13 (nsp13) hijacks host deubiquitinase USP13 and counteracts host antiviral immune response. Signal Transduct Target Ther. 2021;6:119 pubmed publisher
  • western blot; mouse; 1:1000; loading ...; fig 5a
Wang Z, Feng J, Yu J, Chen G. FKBP12 mediates necroptosis by initiating RIPK1-RIPK3-MLKL signal transduction in response to TNF receptor 1 ligation. J Cell Sci. 2019;132: pubmed publisher
  • western blot; mouse; 1:1000; loading ...; fig s9c
Ben J, Jiang B, Wang D, Liu Q, Zhang Y, Qi Y, et al. Major vault protein suppresses obesity and atherosclerosis through inhibiting IKK-NF-κB signaling mediated inflammation. Nat Commun. 2019;10:1801 pubmed publisher
  • western blot; mouse; loading ...; fig 1b
Siegmund D, Ehrenschwender M, Wajant H. TNFR2 unlocks a RIPK1 kinase activity-dependent mode of proinflammatory TNFR1 signaling. Cell Death Dis. 2018;9:921 pubmed publisher
  • western blot; human; loading ...; fig 2a
Ma W, Tummers B, van Esch E, Goedemans R, Melief C, Meyers C, et al. Human Papillomavirus Downregulates the Expression of IFITM1 and RIPK3 to Escape from IFN?- and TNF?-Mediated Antiproliferative Effects and Necroptosis. Front Immunol. 2016;7:496 pubmed
  • western blot; mouse; fig 5
Tortola L, Nitsch R, Bertrand M, Kogler M, Redouane Y, Kozieradzki I, et al. The Tumor Suppressor Hace1 Is a Critical Regulator of TNFR1-Mediated Cell Fate. Cell Rep. 2016;15:1481-1492 pubmed publisher
Diamanti M, Gupta J, Bennecke M, De Oliveira T, Ramakrishnan M, Braczynski A, et al. IKK? controls ATG16L1 degradation to prevent ER stress during inflammation. J Exp Med. 2017;214:423-437 pubmed publisher
Keestra Gounder A, Byndloss M, Seyffert N, Young B, Chávez Arroyo A, Tsai A, et al. NOD1 and NOD2 signalling links ER stress with inflammation. Nature. 2016;532:394-7 pubmed publisher
product information
SKU :
4724S
Product-Name :
TRAF2 (C192) Antibody
Size :
100 ul
Price-(USD) :
235 USD
Species-x-Reactivity :
H, M, Mk
Applications :
Immunoprecipitation
Product-Category :
Apoptosis
Shipping-Temp :
AMBIENT
Storage-Temp :
-20°C
Product-Type :
Polyclonal Antibody
MW :
53
Host :
Rabbit
Target :
TRAF2
Primary-Protein :
TRAF2
Alt-Names :
MGC:45012,TNF receptor-associated factor 2,TRAF2,TRAP,TRAP3,Tumor necrosis factor type 2 receptor-associated protein 3,tumor necrosis factor type 2 receptor associated protein 3
company information
Cell Signaling Technology
3 Trask Lane
Danvers, MA 01923
info@cellsignal.com
https://www.cellsignal.com
8776162355
headquarters: USA
Established in Beverly, MA in 1999, Cell Signaling Technology (CST) is a privately-owned company with over 400 employees worldwide. We are dedicated to providing innovative research tools that are used to help define mechanisms underlying cell function and disease. Since its inception, CST has become the world leader in the production of the highest quality activation-state and total protein antibodies utilized to expand knowledge of cell signaling pathways. Our mission is to deliver the world's highest quality research tools that accelerate progress in biological research and personalized medicine.