product summary
company name :
Cell Signaling Technology
product type :
antibody
product name :
Integrin β1 Antibody
catalog :
4706
clonality :
polyclonal
host :
rabbit
conjugate :
nonconjugated
reactivity :
African green monkey, human, mouse, rat
application :
western blot, immunohistochemistry, immunocytochemistry, immunoprecipitation
citations: 19
Published Application/Species/Sample/DilutionReference
  • western blot; human; 1:500; loading ...; fig 3d
Bayer S, Grither W, Brenot A, Hwang P, Barcus C, Ernst M, et al. DDR2 controls breast tumor stiffness and metastasis by regulating integrin mediated mechanotransduction in CAFs. elife. 2019;8: pubmed publisher
  • immunoprecipitation; human; 1:100; loading ...; fig 8f
  • western blot; human; 1:1000; loading ...; fig 8a
Singh R, Peng S, Viswanath P, Sambandam V, Shen L, Rao X, et al. Non-canonical cMet regulation by vimentin mediates Plk1 inhibitor-induced apoptosis. EMBO Mol Med. 2019;: pubmed publisher
  • western blot; African green monkey; 1:1000; loading ...; fig 1b
Gorla M, Santiago C, Chaudhari K, Layman A, Oliver P, Bashaw G. Ndfip Proteins Target Robo Receptors for Degradation and Allow Commissural Axons to Cross the Midline in the Developing Spinal Cord. Cell Rep. 2019;26:3298-3312.e4 pubmed publisher
  • western blot; human; loading ...; fig 2j
Ren D, Yang Q, Dai Y, Guo W, Du H, Song L, et al. Oncogenic miR-210-3p promotes prostate cancer cell EMT and bone metastasis via NF-?B signaling pathway. Mol Cancer. 2017;16:117 pubmed publisher
  • western blot; human; loading ...; fig 6b
LAW M, Ferreira R, Davis B, Higgins P, Kim J, Castellano R, et al. CUB domain-containing protein 1 and the epidermal growth factor receptor cooperate to induce cell detachment. Breast Cancer Res. 2016;18:80 pubmed publisher
  • immunocytochemistry; mouse; 1:200; fig 1a
  • immunohistochemistry; mouse; 1:200; loading ...; fig s9b
Rozo M, Li L, Fan C. Targeting ?1-integrin signaling enhances regeneration in aged and dystrophic muscle in mice. Nat Med. 2016;22:889-96 pubmed publisher
  • western blot; human; 1:1000; fig 5
Conway A, Van Nostrand E, Pratt G, Aigner S, Wilbert M, Sundararaman B, et al. Enhanced CLIP Uncovers IMP Protein-RNA Targets in Human Pluripotent Stem Cells Important for Cell Adhesion and Survival. Cell Rep. 2016;15:666-679 pubmed publisher
  • western blot; human; fig 4
Kim D, Helfman D. Loss of MLCK leads to disruption of cell-cell adhesion and invasive behavior of breast epithelial cells via increased expression of EGFR and ERK/JNK signaling. Oncogene. 2016;35:4495-508 pubmed publisher
  • immunohistochemistry; mouse; 1:200; fig 6
  • western blot; mouse; 1:1000; fig 6
Zhang Y, Fan J, Ho J, Hu T, Kneeland S, Fan X, et al. Crim1 regulates integrin signaling in murine lens development. Development. 2016;143:356-66 pubmed publisher
  • western blot; human; fig 2a
Fedorenko I, Abel E, Koomen J, Fang B, Wood E, Chen Y, et al. Fibronectin induction abrogates the BRAF inhibitor response of BRAF V600E/PTEN-null melanoma cells. Oncogene. 2016;35:1225-35 pubmed publisher
  • western blot; mouse; fig 1a
Ulaganathan V, Sperl B, Rapp U, Ullrich A. Germline variant FGFR4  p.G388R exposes a membrane-proximal STAT3 binding site. Nature. 2015;528:570-4 pubmed publisher
  • western blot; human; 1:1000; fig 2
Hoshino A, Costa Silva B, Shen T, Rodrigues G, Hashimoto A, Tesic Mark M, et al. Tumour exosome integrins determine organotropic metastasis. Nature. 2015;527:329-35 pubmed publisher
  • western blot; mouse; fig 3d
Carthy J, Meredith A, Boroomand S, Abraham T, Luo Z, Knight D, et al. Versican V1 Overexpression Induces a Myofibroblast-Like Phenotype in Cultured Fibroblasts. PLoS ONE. 2015;10:e0133056 pubmed publisher
  • western blot; human; fig 6
Thieme R, Kurz S, Kolb M, Debebe T, Holtze S, Morhart M, et al. Analysis of Alpha-2 Macroglobulin from the Long-Lived and Cancer-Resistant Naked Mole-Rat and Human Plasma. PLoS ONE. 2015;10:e0130470 pubmed publisher
  • western blot; human; 1:1000; fig 6
Fullár A, Dudás J, Oláh L, Hollósi P, Papp Z, Sobel G, et al. Remodeling of extracellular matrix by normal and tumor-associated fibroblasts promotes cervical cancer progression. BMC Cancer. 2015;15:256 pubmed publisher
  • immunocytochemistry; human; 2 ug/ml
Rappa G, Green T, Karbanová J, Corbeil D, Lorico A. Tetraspanin CD9 determines invasiveness and tumorigenicity of human breast cancer cells. Oncotarget. 2015;6:7970-91 pubmed
  • western blot; human; fig s1l
Boucrot E, Ferreira A, Almeida Souza L, Debard S, Vallis Y, Howard G, et al. Endophilin marks and controls a clathrin-independent endocytic pathway. Nature. 2015;517:460-5 pubmed publisher
  • western blot; human; 1:3000
Zhang H, Chen Y, Wadham C, McCaughan G, Keane F, Gorrell M. Dipeptidyl peptidase 9 subcellular localization and a role in cell adhesion involving focal adhesion kinase and paxillin. Biochim Biophys Acta. 2015;1853:470-80 pubmed publisher
  • western blot; human
Eucker T, Samuelson D, Hunzicker Dunn M, Konkel M. The focal complex of epithelial cells provides a signalling platform for interleukin-8 induction in response to bacterial pathogens. Cell Microbiol. 2014;16:1441-55 pubmed publisher
product information
SKU :
4706S
Product-Name :
Integrin β1 Antibody
Size :
100 ul
Price-(USD) :
235 USD
Species-x-Reactivity :
H, M, R, Mk
Applications :
Western blot
Product-Category :
Adhesion/ECM
Shipping-Temp :
COLD
Storage-Temp :
-20°C
Product-Type :
Polyclonal Antibody
MW :
115, 135
Host :
Rabbit
Target :
Integrin Beta1
Primary-Protein :
ITGB1
Alt-Names :
CD29,FNRB,Fibronectin receptor subunit beta,GPIIA,ITB1,ITGB1,Integrin beta-1,MDF2,MSK12,VLA-4 subunit beta,VLA-BETA,VLAB,fibronectin receptor beta subunit,integrin VLA-4 beta subunit,integrin, beta 1 (fibronectin receptor, beta polypeptide, antigen CD29 includes MDF2, MSK12)
company information
Cell Signaling Technology
3 Trask Lane
Danvers, MA 01923
info@cellsignal.com
https://www.cellsignal.com
8776162355
headquarters: USA
Established in Beverly, MA in 1999, Cell Signaling Technology (CST) is a privately-owned company with over 400 employees worldwide. We are dedicated to providing innovative research tools that are used to help define mechanisms underlying cell function and disease. Since its inception, CST has become the world leader in the production of the highest quality activation-state and total protein antibodies utilized to expand knowledge of cell signaling pathways. Our mission is to deliver the world's highest quality research tools that accelerate progress in biological research and personalized medicine.