product summary
company name :
Cell Signaling Technology
product type :
antibody
product name :
MEK1/2 (L38C12) Mouse mAb
catalog :
4694S
quantity :
100 ul
price :
235 USD
clonality :
monoclonal
host :
mouse
reactivity :
human, mouse
application :
western blot, immunohistochemistry, immunocytochemistry, flow cytometry
more info or order :
Cell Signaling Technology product webpage
citations: 8
Published Application/Species/DilutionReference
  • western blot; human
Choi J, Landrette S, Wang T, Evans P, Bacchiocchi A, Bjornson R, et al. Identification of PLX4032-resistance mechanisms and implications for novel RAF inhibitors. Pigment Cell Melanoma Res. 2014;27:253-62 pubmed publisher
  • western blot; mouse
Park E, Kim B, Lee E, Chang E, Kim D, Choi S, et al. Targeting of receptor for advanced glycation end products suppresses cyst growth in polycystic kidney disease. J Biol Chem. 2014;289:9254-62 pubmed publisher
Carlino M, Fung C, Shahheydari H, Todd J, Boyd S, Irvine M, et al. Preexisting MEK1P124 mutations diminish response to BRAF inhibitors in metastatic melanoma patients. Clin Cancer Res. 2015;21:98-105 pubmed publisher
Rizos H, Menzies A, Pupo G, Carlino M, Fung C, Hyman J, et al. BRAF inhibitor resistance mechanisms in metastatic melanoma: spectrum and clinical impact. Clin Cancer Res. 2014;20:1965-77 pubmed publisher
Mayes D, Rizvi T, Titus-Mitchell H, Oberst R, Ciraolo G, Vorhees C, et al. Nf1 loss and Ras hyperactivation in oligodendrocytes induce NOS-driven defects in myelin and vasculature. Cell Rep. 2013;4:1197-212 pubmed publisher
Satoh T, Smith A, Sarde A, Lu H, Mian S, Mian S, et al. B-RAF mutant alleles associated with Langerhans cell histiocytosis, a granulomatous pediatric disease. PLoS ONE. 2012;7:e33891 pubmed publisher
Lee J, Huang S, Lee M, Lee S, Ryu M, Kim S, et al. Dual specificity phosphatase 6 as a predictor of invasiveness in papillary thyroid cancer. Eur J Endocrinol. 2012;167:93-101 pubmed publisher
Falco A, Festa M, Basile A, Rosati A, Pascale M, Florenzano F, et al. BAG3 controls angiogenesis through regulation of ERK phosphorylation. Oncogene. 2012;31:5153-61 pubmed publisher
product information
SKU :
4694S
Product-Name :
MEK1/2 (L38C12) Mouse mAb
Size :
100 ul
Price-(USD) :
235 USD
Species-x-Reactivity :
H, M, R, Mk
Applications :
Flow cytometry
Product-Category :
MAP Kinase Signaling
Shipping-Temp :
AMBIENT
Storage-Temp :
-20°C
Product-Type :
Monoclonal Antibody
MW :
45
Host :
Mouse
Target :
MEK1/MEK2
more info or order :
Cell Signaling Technology product webpage
company information
Cell Signaling Technology
3 Trask Lane
Danvers, MA 01923
info@cellsignal.com
www.cellsignal.com
8776162355
headquarters: USA
Established in Beverly, MA in 1999, Cell Signaling Technology (CST) is a privately-owned company with over 400 employees worldwide. We are dedicated to providing innovative research tools that are used to help define mechanisms underlying cell function and disease. Since its inception, CST has become the world leader in the production of the highest quality activation-state and total protein antibodies utilized to expand knowledge of cell signaling pathways. Our mission is to deliver the world's highest quality research tools that accelerate progress in biological research and personalized medicine.