product summary
company name :
Cell Signaling Technology
product type :
antibody
product name :
cdc25C (5H9) Rabbit mAb
catalog :
4688
clonality :
monoclonal
host :
rabbit
conjugate :
nonconjugated
clone name :
5H9
reactivity :
human, mouse, rat
application :
western blot, immunohistochemistry, other
citations: 21
Published Application/Species/Sample/DilutionReference
  • other; human; loading ...; fig 4c
Ng P, Li J, Jeong K, Shao S, Chen H, Tsang Y, et al. Systematic Functional Annotation of Somatic Mutations in Cancer. Cancer Cell. 2018;33:450-462.e10 pubmed publisher
  • western blot; human; loading ...; fig 2a, 2b
Karanika S, Karantanos T, Li L, Wang J, Park S, Yang G, et al. Targeting DNA Damage Response in Prostate Cancer by Inhibiting Androgen Receptor-CDC6-ATR-Chk1 Signaling. Cell Rep. 2017;18:1970-1981 pubmed publisher
  • western blot; human; loading ...; fig 3
Kozakai Y, Kamada R, Furuta J, Kiyota Y, Chuman Y, Sakaguchi K. PPM1D controls nucleolar formation by up-regulating phosphorylation of nucleophosmin. Sci Rep. 2016;6:33272 pubmed publisher
  • western blot; rat; fig 6d
Bartlett J, Trivedi P, Yeung P, Kienesberger P, Pulinilkunnil T. Doxorubicin impairs cardiomyocyte viability by suppressing transcription factor EB expression and disrupting autophagy. Biochem J. 2016;473:3769-3789 pubmed
  • western blot; rat; 1:800; fig 6
Jiao K, Zeng G, Niu L, Yang H, Ren G, Xu X, et al. Activation of ?2A-adrenergic signal transduction in chondrocytes promotes degenerative remodelling of temporomandibular joint. Sci Rep. 2016;6:30085 pubmed publisher
  • immunohistochemistry; human; fig 7
  • western blot; human; fig 5
Chen X, Stauffer S, Chen Y, Dong J. Ajuba Phosphorylation by CDK1 Promotes Cell Proliferation and Tumorigenesis. J Biol Chem. 2016;291:14761-72 pubmed publisher
  • western blot; human; loading ...; fig s5a
Bouhlal H, Ouled Haddou H, Debuysscher V, Singh A, Ossart C, Reignier A, et al. RB/PLK1-dependent induced pathway by SLAMF3 expression inhibits mitosis and control hepatocarcinoma cell proliferation. Oncotarget. 2016;7:9832-43 pubmed publisher
  • western blot; human; loading ...; fig 5a
García V, Lara Chica M, Cantarero I, Sterner O, Calzado M, Muñoz E. Galiellalactone induces cell cycle arrest and apoptosis through the ATM/ATR pathway in prostate cancer cells. Oncotarget. 2016;7:4490-506 pubmed publisher
  • western blot; human; fig 4
Chiang K, Chen H, Hsu S, Pang J, Wang S, Hsu J, et al. PTEN insufficiency modulates ER+ breast cancer cell cycle progression and increases cell growth in vitro and in vivo. Drug Des Devel Ther. 2015;9:4631-8 pubmed publisher
  • western blot; mouse; fig 1, 7
Sahu S, Garding A, Tiwari N, Thakurela S, Toedling J, Gebhard S, et al. JNK-dependent gene regulatory circuitry governs mesenchymal fate. EMBO J. 2015;34:2162-81 pubmed publisher
  • western blot; human; 1:1000
Pang C, Toh S, He P, Teissier S, Ben Khalifa Y, Xue Y, et al. A functional interaction of E7 with B-Myb-MuvB complex promotes acute cooperative transcriptional activation of both S- and M-phase genes. (129 c). Oncogene. 2014;33:4039-49 pubmed publisher
Lin C, Pan I, Li Y, Pan Y, Lin M, Lu Y, et al. The adjuvant effects of high-molecule-weight polysaccharides purified from Antrodia cinnamomea on dendritic cell function and DNA vaccines. PLoS ONE. 2015;10:e0116191 pubmed publisher
Lv C, Qin W, Zhu T, Wei S, Hong K, Zhu W, et al. Ophiobolin O isolated from Aspergillus ustus induces G1 arrest of MCF-7 cells through interaction with AKT/GSK3β/cyclin D1 signaling. Mar Drugs. 2015;13:431-43 pubmed publisher
Yen C, Hsiao C, Chen W, Wen Y, Lin Y, Chang T, et al. Cytotoxic effects of 15d-PGJ2 against osteosarcoma through ROS-mediated AKT and cell cycle inhibition. Oncotarget. 2014;5:716-25 pubmed
Zhou Y, Shu F, Liang X, Chang H, Shi L, Peng X, et al. Ampelopsin induces cell growth inhibition and apoptosis in breast cancer cells through ROS generation and endoplasmic reticulum stress pathway. PLoS ONE. 2014;9:e89021 pubmed publisher
Hwang B, Shi G, Lu A. Mammalian MutY homolog (MYH or MUTYH) protects cells from oxidative DNA damage. DNA Repair (Amst). 2014;13:10-21 pubmed publisher
Chen M, Li W, Lue Y, Chu C, Pan I, Ko C, et al. Clitocybe nuda Activates Dendritic Cells and Acts as a DNA Vaccine Adjuvant. Evid Based Complement Alternat Med. 2013;2013:761454 pubmed publisher
Gamper A, Rofougaran R, Watkins S, Greenberger J, Beumer J, Bakkenist C. ATR kinase activation in G1 phase facilitates the repair of ionizing radiation-induced DNA damage. Nucleic Acids Res. 2013;41:10334-44 pubmed publisher
Sousa M, Zub K, Aas P, Hanssen Bauer A, Demirovic A, Sarno A, et al. An inverse switch in DNA base excision and strand break repair contributes to melphalan resistance in multiple myeloma cells. PLoS ONE. 2013;8:e55493 pubmed publisher
Ma Y, Zhou Y, Xie C, Chen D, Li J. Novel microtubule-targeted agent 6-chloro-4-(methoxyphenyl) coumarin induces G2-M arrest and apoptosis in HeLa cells. Acta Pharmacol Sin. 2012;33:407-17 pubmed publisher
Hegemann B, Hutchins J, Hudecz O, Novatchkova M, Rameseder J, Sykora M, et al. Systematic phosphorylation analysis of human mitotic protein complexes. Sci Signal. 2011;4:rs12 pubmed publisher
product information
SKU :
4688P
Product-Name :
cdc25C (5H9) Rabbit mAb
Size :
40 ul
Price-(USD) :
123 USD
Species-x-Reactivity :
H
Applications :
Western blot
Product-Category :
Cell Cycle / Checkpoint Control
Shipping-Temp :
AMBIENT
Storage-Temp :
-20°C
Product-Type :
Monoclonal Antibody
MW :
60, 75
Host :
Rabbit
Target :
Cdc25c
Primary-Protein :
Cdc25C
Alt-Names :
CDC25,CDC25C,Dual specificity phosphatase Cdc25C,M-phase inducer phosphatase 3,MPIP3,cell division cycle 25 homolog C (S. pombe),cell division cycle 25C,mitosis inducer CDC25,phosphotyrosine phosphatase
company information
Cell Signaling Technology
3 Trask Lane
Danvers, MA 01923
info@cellsignal.com
www.cellsignal.com
8776162355
headquarters: USA
Established in Beverly, MA in 1999, Cell Signaling Technology (CST) is a privately-owned company with over 400 employees worldwide. We are dedicated to providing innovative research tools that are used to help define mechanisms underlying cell function and disease. Since its inception, CST has become the world leader in the production of the highest quality activation-state and total protein antibodies utilized to expand knowledge of cell signaling pathways. Our mission is to deliver the world's highest quality research tools that accelerate progress in biological research and personalized medicine.