product summary
company name :
Cell Signaling Technology
product type :
antibody
product name :
β-Arrestin 1/2 (D24H9) Rabbit mAb
catalog :
4674
clonality :
monoclonal
host :
domestic rabbit
conjugate :
nonconjugated
clone name :
D24H9
reactivity :
human, mouse, rat
application :
western blot, immunoprecipitation
citations: 12
Published Application/Species/Sample/DilutionReference
  • western blot; human; 1:1000; loading ...; fig 3g
De Groof T, Bergkamp N, Heukers R, Giap T, Bebelman M, Goeij de Haas R, et al. Selective targeting of ligand-dependent and -independent signaling by GPCR conformation-specific anti-US28 intrabodies. Nat Commun. 2021;12:4357 pubmed publisher
  • western blot; mouse; 1:1000; loading ...; fig 3f
Bele S, Girada S, Ray A, Gupta A, Oruganti S, Prakash Babu P, et al. MS-275, a class 1 histone deacetylase inhibitor augments glucagon-like peptide-1 receptor agonism to improve glycemic control and reduce obesity in diet-induced obese mice. elife. 2020;9: pubmed publisher
  • western blot; rat; 1:1000; fig s9
Cannavo A, Liccardo D, Eguchi A, Elliott K, Traynham C, Ibetti J, et al. Myocardial pathology induced by aldosterone is dependent on non-canonical activities of G protein-coupled receptor kinases. Nat Commun. 2016;7:10877 pubmed publisher
  • immunoprecipitation; human; 1:1000; fig 2
  • western blot; human; 1:1000; fig 2
Vukićević T, Schulz M, Faust D, Klussmann E. The Trafficking of the Water Channel Aquaporin-2 in Renal Principal Cells-a Potential Target for Pharmacological Intervention in Cardiovascular Diseases. Front Pharmacol. 2016;7:23 pubmed publisher
  • western blot; human; 1:1000; fig 5
Werner A, Iwasaki S, McGourty C, Medina Ruiz S, Teerikorpi N, Fedrigo I, et al. Cell-fate determination by ubiquitin-dependent regulation of translation. Nature. 2015;525:523-7 pubmed publisher
  • immunoprecipitation; human
  • western blot; human
Ghorbani A, Jeddi Tehrani M, Saidpour A, Safa M, Bayat A, Zand H. PI3K/AKT and Mdm2 activation are associated with inhibitory effect of cAMP increasing agents on DNA damage-induced cell death in human pre-B NALM-6 cells. Arch Biochem Biophys. 2015;566:58-66 pubmed publisher
  • western blot; mouse; 1:5000
Fraisier C, Koraka P, Belghazi M, Bakli M, Granjeaud S, Pophillat M, et al. Kinetic analysis of mouse brain proteome alterations following Chikungunya virus infection before and after appearance of clinical symptoms. PLoS ONE. 2014;9:e91397 pubmed publisher
Thibeault P, LeSarge J, Arends D, Fernandes M, Chidiac P, Stathopulos P, et al. Molecular basis for activation and biased signaling at the thrombin-activated GPCR proteinase activated receptor-4 (PAR4). J Biol Chem. 2020;295:2520-2540 pubmed publisher
Jones B, Buenaventura T, Kanda N, Chabosseau P, Owen B, Scott R, et al. Targeting GLP-1 receptor trafficking to improve agonist efficacy. Nat Commun. 2018;9:1602 pubmed publisher
Masannat J, Purayil H, Zhang Y, Russin M, Mahmud I, Kim W, et al. βArrestin2 Mediates Renal Cell Carcinoma Tumor Growth. Sci Rep. 2018;8:4879 pubmed publisher
Buenaventura T, Kanda N, Douzenis P, Jones B, Bloom S, Chabosseau P, et al. A Targeted RNAi Screen Identifies Endocytic Trafficking Factors That Control GLP-1 Receptor Signaling in Pancreatic β-Cells. Diabetes. 2018;67:385-399 pubmed publisher
Canals M, Scholten D, de Munnik S, Han M, Smit M, Leurs R. Ubiquitination of CXCR7 controls receptor trafficking. PLoS ONE. 2012;7:e34192 pubmed publisher
product information
SKU :
4674S
Product-Name :
β-Arrestin 1/2 (D24H9) Rabbit mAb
Size :
100 ul
Price-(USD) :
235 USD
Species-x-Reactivity :
H, M, R, Mk
Applications :
Immunoprecipitation
Product-Category :
MAP Kinase Signaling
Shipping-Temp :
AMBIENT
Storage-Temp :
-20°C
Product-Type :
Monoclonal Antibody
MW :
50
Host :
Rabbit
Target :
Arrestin, beta1/Arrestin, beta2
company information
Cell Signaling Technology
3 Trask Lane
Danvers, MA 01923
info@cellsignal.com
https://www.cellsignal.com
8776162355
headquarters: USA
Established in Beverly, MA in 1999, Cell Signaling Technology (CST) is a privately-owned company with over 400 employees worldwide. We are dedicated to providing innovative research tools that are used to help define mechanisms underlying cell function and disease. Since its inception, CST has become the world leader in the production of the highest quality activation-state and total protein antibodies utilized to expand knowledge of cell signaling pathways. Our mission is to deliver the world's highest quality research tools that accelerate progress in biological research and personalized medicine.