product summary
company name :
Cell Signaling Technology
product type :
antibody
product name :
Phospho-SAPK/JNK (Thr183/Tyr185) (98F2) Rabbit mAb
catalog :
4671S
quantity :
200 ul
price :
274 USD
clonality :
monoclonal
host :
rabbit
antigen modification :
phosphorylated
reactivity :
human, mouse, rat
application :
western blot
citations: 22
Published Application/Species/DilutionReference
  • western blot; human; fig 4
Chusri P, Kumthip K, Hong J, Zhu C, Duan X, Jilg N, et al. HCV induces transforming growth factor β1 through activation of endoplasmic reticulum stress and the unfolded protein response. Sci Rep. 2016;6:22487 pubmed publisher
  • western blot; rat; 1:1000; fig 3
Liu L, Lv G, Ning C, Yang Y, Zhu J. Therapeutic effects of 1,25-dihydroxyvitamin D3 on diabetes-induced liver complications in a rat model. Exp Ther Med. 2016;11:2284-2292 pubmed
  • western blot; human; fig 2
Trapé A, Liu S, Cortés A, Ueno N, Gonzalez-Angulo A. Effects of CDK4/6 Inhibition in Hormone Receptor-Positive/Human Epidermal Growth Factor Receptor 2-Negative Breast Cancer Cells with Acquired Resistance to Paclitaxel. J Cancer. 2016;7:947-56 pubmed publisher
  • western blot; mouse; 1:800; fig 4
Lin Y, Zhuang J, Li H, Zhu G, Zhou S, Li W, et al. Vaspin attenuates the progression of atherosclerosis by inhibiting ER stress‑induced macrophage apoptosis in apoE‑/‑ mice. Mol Med Rep. 2016;13:1509-16 pubmed publisher
  • western blot; rat
Shen X, Yang L, Yan S, Zheng H, Liang L, Cai X, et al. Fetuin A promotes lipotoxicity in β cells through the TLR4 signaling pathway and the role of pioglitazone in anti-lipotoxicity. Mol Cell Endocrinol. 2015;412:1-11 pubmed publisher
  • western blot; human
Lee C, Yang Y, Chen C, Liu J. Syk-mediated tyrosine phosphorylation of mule promotes TNF-induced JNK activation and cell death. Oncogene. 2015;: pubmed publisher
  • western blot; mouse
Krokowski D, Jobava R, Guan B, Farabaugh K, Wu J, Majumder M, et al. Coordinated Regulation of the Neutral Amino Acid Transporter SNAT2 and the Protein Phosphatase Subunit GADD34 Promotes Adaptation to Increased Extracellular Osmolarity. J Biol Chem. 2015;290:17822-37 pubmed publisher
  • western blot; rat; fig s5
Wang J, Cao Y, Li Q, Yang Y, Jin M, Chen D, et al. A pivotal role of FOS-mediated BECN1/Beclin 1 upregulation in dopamine D2 and D3 receptor agonist-induced autophagy activation. Autophagy. 2015;11:2057-2073 pubmed
  • western blot; mouse; 1:500; fig 4
Boncompagni S, Arthurton L, Akujuru E, Pearson T, Steverding D, Protasi F, et al. Membrane glucocorticoid receptors are localised in the extracellular matrix and signal through the MAPK pathway in mammalian skeletal muscle fibres. J Physiol. 2015;593:2679-92 pubmed publisher
  • western blot; mouse; fig 6
Pajaud J, Ribault C, Ben Mosbah I, Rauch C, Henderson C, Bellaud P, et al. Glutathione transferases P1/P2 regulate the timing of signaling pathway activations and cell cycle progression during mouse liver regeneration. Cell Death Dis. 2015;6:e1598 pubmed publisher
  • western blot; human; 1:1000
Zanotto-Filho A, Braganhol E, Klafke K, Figueiró F, Terra S, Paludo F, et al. Autophagy inhibition improves the efficacy of curcumin/temozolomide combination therapy in glioblastomas. Cancer Lett. 2015;358:220-31 pubmed publisher
  • western blot; rat
Beaudoin M, Snook L, Arkell A, Stefanson A, Wan Z, Simpson J, et al. Novel effects of rosiglitazone on SMAD2 and SMAD3 signaling in white adipose tissue of diabetic rats. Obesity (Silver Spring). 2014;22:1632-42 pubmed publisher
  • western blot; human
Côté-Maurais G, Bernier J. Silver and fullerene nanoparticles' effect on interleukin-2-dependent proliferation of CD4 (+) T cells. Toxicol In Vitro. 2014;28:1474-81 pubmed publisher
  • western blot; human; 1:1000
Geissler A, Haun F, Frank D, Wieland K, Simon M, Idzko M, et al. Apoptosis induced by the fungal pathogen gliotoxin requires a triple phosphorylation of Bim by JNK. Cell Death Differ. 2013;20:1317-29 pubmed publisher
  • western blot; mouse
Rui T, Tang Q. IL-33 attenuates anoxia/reoxygenation-induced cardiomyocyte apoptosis by inhibition of PKCβ/JNK pathway. PLoS ONE. 2013;8:e56089 pubmed publisher
Cranford T, Enos R, Velázquez K, McClellan J, Davis J, Singh U, et al. Role of MCP-1 on inflammatory processes and metabolic dysfunction following high-fat feedings in the FVB/N strain. Int J Obes (Lond). 2016;40:844-51 pubmed publisher
Garcia D, de Castro-Faria-Neto H, da Silva C, de Souza e Souza K, Gonçalves-de-Albuquerque C, Silva A, et al. Na/K-ATPase as a target for anticancer drugs: studies with perillyl alcohol. Mol Cancer. 2015;14:105 pubmed publisher
Liu J, Sun K, Zheng C, Chen X, Zhang W, Wang Z, et al. Pathway as a pharmacological target for herbal medicines: an investigation from reduning injection. PLoS ONE. 2015;10:e0123109 pubmed publisher
Morishige T, Yoshioka Y, Inakura H, Tanabe A, Narimatsu S, Yao X, et al. Suppression of nanosilica particle-induced inflammation by surface modification of the particles. Arch Toxicol. 2012;86:1297-307 pubmed publisher
Castro A, Campos T, Babcock J, Armijo M, Martínez-Conde A, Pincheira R, et al. M-Ras induces Ral and JNK activation to regulate MEK/ERK-independent gene expression in MCF-7 breast cancer cells. J Cell Biochem. 2012;113:1253-64 pubmed publisher
Schindler M, Fabre C, de Weille J, Carreau S, Mersel M, Bakalara N. Disruption of nongenomic testosterone signaling in a model of spinal and bulbar muscular atrophy. Mol Endocrinol. 2012;26:1102-16 pubmed publisher
Heimfarth L, Reis K, Loureiro S, de Lima B, da Rocha J, Pessoa-Pureur R. Exposure of young rats to diphenyl ditelluride during lactation affects the homeostasis of the cytoskeleton in neural cells from striatum and cerebellum. Neurotoxicology. 2012;33:1106-16 pubmed publisher
product information
SKU :
4671S
Product-Name :
Phospho-SAPK/JNK (Thr183/Tyr185) (98F2) Rabbit mAb
Size :
200 ul
Price-(USD) :
274 USD
Species-x-Reactivity :
H, M, R, Hm
Applications :
Western blot
Product-Category :
MAP Kinase Signaling
Shipping-Temp :
AMBIENT
Storage-Temp :
-20°C
Product-Type :
Monoclonal Antibody
MW :
46, 54
Host :
Rabbit
Target :
SAPK/JNK1 (Thr183/Tyr185) phosphate
Primary-Protein :
JNK1
Alt-Names :
JNK,JNK-46,JNK1,JNK1 alpha protein kinase,JNK1 beta protein kinase,JNK1A2,JNK21B1/2,JUN N-terminal kinase,MAP kinase 8,MAPK 8,MAPK8,MK08,Mitogen-activated protein kinase 8,PRKM8,SAPK1,Stress-activated protein kinase 1,Stress-activated protein kinase JNK1,c-Jun N-terminal kinase 1,mitogen-activated protein kinase 8 isoform JNK1 alpha1,mitogen-activated protein kinase 8 isoform JNK1 beta2,protein kinase JNK1
company information
Cell Signaling Technology
3 Trask Lane
Danvers, MA 01923
info@cellsignal.com
www.cellsignal.com
8776162355
headquarters: USA
Established in Beverly, MA in 1999, Cell Signaling Technology (CST) is a privately-owned company with over 400 employees worldwide. We are dedicated to providing innovative research tools that are used to help define mechanisms underlying cell function and disease. Since its inception, CST has become the world leader in the production of the highest quality activation-state and total protein antibodies utilized to expand knowledge of cell signaling pathways. Our mission is to deliver the world's highest quality research tools that accelerate progress in biological research and personalized medicine.