product summary
company name :
Cell Signaling Technology
product type :
antibody
product name :
AIF Antibody
catalog :
4642
clonality :
polyclonal
host :
rabbit
conjugate :
nonconjugated
reactivity :
human, mouse, rat
application :
western blot, immunohistochemistry, immunocytochemistry, immunoprecipitation
citations: 22
Published Application/Species/Sample/DilutionReference
  • western blot; rat; 1:500; fig 5
Jeong J, Noh M, Choi J, Lee H, Kim S. Neuroprotective and antioxidant activities of bamboo salt soy sauce against H2O2-induced oxidative stress in rat cortical neurons. Exp Ther Med. 2016;11:1201-1210 pubmed
  • immunohistochemistry; mouse; 1:100; fig 2e
Lei L, Spradling A. Mouse oocytes differentiate through organelle enrichment from sister cyst germ cells. Science. 2016;352:95-9 pubmed publisher
  • western blot; human; 1:1000; fig 3
Gao S, Chen X, Jin H, Ren S, Liu Z, Fang X, et al. Overexpression of ErbB2 renders breast cancer cells susceptible to 3-BrPA through the increased dissociation of hexokinase II from mitochondrial outer membrane. Oncol Lett. 2016;11:1567-1573 pubmed
  • western blot; human; 1:2000; loading ...; fig 4b
Guo W, Zhang Y, Ling Z, Liu X, Zhao X, Yuan Z, et al. Caspase-3 feedback loop enhances Bid-induced AIF/endoG and Bak activation in Bax and p53-independent manner. Cell Death Dis. 2015;6:e1919 pubmed publisher
  • western blot; rat; 1:1000; loading ...; fig 7a
Cheng C, Lin J, Tang N, Kao S, Hsieh C. Electroacupuncture at different frequencies (5Hz and 25Hz) ameliorates cerebral ischemia-reperfusion injury in rats: possible involvement of p38 MAPK-mediated anti-apoptotic signaling pathways. BMC Complement Altern Med. 2015;15:241 pubmed publisher
  • western blot; human; 1:2000; loading ...; fig 1C
Wang J, Guo W, Zhou H, Luo N, Nie C, Zhao X, et al. Mitochondrial p53 phosphorylation induces Bak-mediated and caspase-independent cell death. Oncotarget. 2015;6:17192-205 pubmed
  • western blot; mouse
Kim S, Nam S, Friedman M. The Tomato Glycoalkaloid α-Tomatine Induces Caspase-Independent Cell Death in Mouse Colon Cancer CT-26 Cells and Transplanted Tumors in Mice. J Agric Food Chem. 2015;63:1142-1150 pubmed publisher
  • western blot; human; 1:1000
Meng P, Yoshida H, Tanji K, Matsumiya T, Xing F, Hayakari R, et al. Carnosic acid attenuates apoptosis induced by amyloid-β 1-42 or 1-43 in SH-SY5Y human neuroblastoma cells. Neurosci Res. 2015;94:1-9 pubmed publisher
Eros K, Magyar K, Deres L, Skazel A, Riba A, Vamos Z, et al. Chronic PARP-1 inhibition reduces carotid vessel remodeling and oxidative damage of the dorsal hippocampus in spontaneously hypertensive rats. PLoS ONE. 2017;12:e0174401 pubmed publisher
Cheng C, Tang N, Kao S, Hsieh C. Ferulic Acid Administered at Various Time Points Protects against Cerebral Infarction by Activating p38 MAPK/p90RSK/CREB/Bcl-2 Anti-Apoptotic Signaling in the Subacute Phase of Cerebral Ischemia-Reperfusion Injury in Rats. PLoS ONE. 2016;11:e0155748 pubmed publisher
Miwa S, Treumann A, Bell A, Vistoli G, Nelson G, Hay S, et al. Carboxylesterase converts Amplex red to resorufin: Implications for mitochondrial H2O2 release assays. Free Radic Biol Med. 2016;90:173-83 pubmed publisher
Shen S, Guo M, Xiong Z, Yu Y, Zhao X, Zhang F, et al. AIF inhibits tumor metastasis by protecting PTEN from oxidation. EMBO Rep. 2015;16:1563-80 pubmed publisher
Ward C, Boggio K, Johnson B, Boyd J, Douthwright S, Shaffer S, et al. A loss of FUS/TLS function leads to impaired cellular proliferation. Cell Death Dis. 2014;5:e1572 pubmed publisher
Sargeant T, Lloyd Lewis B, Resemann H, Ramos Montoya A, Skepper J, Watson C. Stat3 controls cell death during mammary gland involution by regulating uptake of milk fat globules and lysosomal membrane permeabilization. Nat Cell Biol. 2014;16:1057-1068 pubmed publisher
Westrate L, Drocco J, Martin K, Hlavacek W, Mackeigan J. Mitochondrial morphological features are associated with fission and fusion events. PLoS ONE. 2014;9:e95265 pubmed publisher
Miskimins W, Ahn H, Kim J, Ryu S, Jung Y, Choi J. Synergistic anti-cancer effect of phenformin and oxamate. PLoS ONE. 2014;9:e85576 pubmed publisher
Giansanti V, Rodriguez G, Savoldelli M, Gioia R, Forlino A, Mazzini G, et al. Characterization of stress response in human retinal epithelial cells. J Cell Mol Med. 2013;17:103-15 pubmed publisher
Messner B, Frotschnig S, Steinacher Nigisch A, Winter B, Eichmair E, Gebetsberger J, et al. Apoptosis and necrosis: two different outcomes of cigarette smoke condensate-induced endothelial cell death. Cell Death Dis. 2012;3:e424 pubmed publisher
Goonetilleke U, Scarborough M, Ward S, Hussain S, Kadioglu A, Gordon S. Death is associated with complement C3 depletion in cerebrospinal fluid of patients with pneumococcal meningitis. MBio. 2012;3: pubmed publisher
Moore F, Santin I, Nogueira T, Gurzov E, Marselli L, Marchetti P, et al. The transcription factor C/EBP delta has anti-apoptotic and anti-inflammatory roles in pancreatic beta cells. PLoS ONE. 2012;7:e31062 pubmed publisher
Selimovic D, Sprenger A, Hannig M, Haikel Y, Hassan M. Apoptosis related protein-1 triggers melanoma cell death via interaction with the juxtamembrane region of p75 neurotrophin receptor. J Cell Mol Med. 2012;16:349-61 pubmed publisher
Pua H, Guo J, Komatsu M, He Y. Autophagy is essential for mitochondrial clearance in mature T lymphocytes. J Immunol. 2009;182:4046-55 pubmed publisher
product information
SKU :
4642S
Product-Name :
AIF Antibody
Size :
100 ul
Price-(USD) :
235 USD
Species-x-Reactivity :
H, M, R
Applications :
Immunofluorescence (Immunocytochemistry)
Product-Category :
Apoptosis
Shipping-Temp :
AMBIENT
Storage-Temp :
-20°C
Product-Type :
Polyclonal Antibody
MW :
57, 67
Host :
Rabbit
Target :
PDCD8
Primary-Protein :
PDCD8
Alt-Names :
AIF,AIFM1,Apoptosis-inducing factor 1, mitochondrial,MGC111425,PDCD8,Programmed cell death protein 8,apoptosis-inducing factor, mitochondrion-associated, 1,programmed cell death 8 (apoptosis-inducing factor),striatal apoptosis-inducing factor
company information
Cell Signaling Technology
3 Trask Lane
Danvers, MA 01923
info@cellsignal.com
www.cellsignal.com
8776162355
headquarters: USA
Established in Beverly, MA in 1999, Cell Signaling Technology (CST) is a privately-owned company with over 400 employees worldwide. We are dedicated to providing innovative research tools that are used to help define mechanisms underlying cell function and disease. Since its inception, CST has become the world leader in the production of the highest quality activation-state and total protein antibodies utilized to expand knowledge of cell signaling pathways. Our mission is to deliver the world's highest quality research tools that accelerate progress in biological research and personalized medicine.