product summary
company name :
Cell Signaling Technology
product type :
antibody
product name :
Doublecortin Antibody
catalog :
4604
clonality :
polyclonal
host :
domestic rabbit
conjugate :
nonconjugated
reactivity :
African green monkey, human, mouse, rat
application :
western blot, immunohistochemistry, immunocytochemistry, immunoprecipitation, flow cytometry, immunohistochemistry - frozen section, immunohistochemistry - free floating section
citations: 26
Published Application/Species/Sample/DilutionReference
  • immunohistochemistry - free floating section; mouse; 1:200; loading ...; fig 5c
Lim J, Tai H, Liao W, Chu Y, Hao C, Huang Y, et al. ASIC1a is required for neuronal activation via low-intensity ultrasound stimulation in mouse brain. elife. 2021;10: pubmed publisher
  • immunohistochemistry; mouse; loading ...; fig s3c
Wang W, Zhao X, Shao Y, Duan X, Wang Y, Li J, et al. Mutation-induced DNMT1 cleavage drives neurodegenerative disease. Sci Adv. 2021;7:eabe8511 pubmed publisher
  • immunohistochemistry - frozen section; mouse; loading ...; fig 4d
Sahu M, Pazos Boubeta Y, Steinzeig A, Kaurinkoski K, Palmisano M, Borowecki O, et al. Depletion of TrkB Receptors From Adult Serotonergic Neurons Increases Brain Serotonin Levels, Enhances Energy Metabolism and Impairs Learning and Memory. Front Mol Neurosci. 2021;14:616178 pubmed publisher
  • immunohistochemistry; rat; 1:500; loading ...; fig 4b
Correll E, Ramser B, Knott M, McCullumsmith R, McGuire J, Ngwenya L. Deficits in pattern separation and dentate gyrus proliferation after rodent lateral fluid percussion injury. IBRO Neurosci Rep. 2021;10:31-41 pubmed publisher
  • immunohistochemistry; rat; loading ...; fig 1a
  • western blot; African green monkey; loading ...; fig 6a
Liu R, Ma J, Wang B, Tian T, Guo N, Liu S. No DCX-positive neurogenesis in the cerebral cortex of the adult primate. Neural Regen Res. 2020;15:1290-1299 pubmed publisher
  • immunohistochemistry; mouse; 1:300; loading ...; fig 2c
Zhu Q, Zhang N, Hu N, Jiang R, Lu H, Xuan A, et al. Neural stem cell transplantation improves learning and memory by protecting cholinergic neurons and restoring synaptic impairment in an amyloid precursor protein/presenilin 1 transgenic mouse model of Alzheimer's disease. Mol Med Rep. 2020;21:1172-1180 pubmed publisher
  • immunocytochemistry; human; 1:200; loading ...; fig 1b
  • western blot; human; 1:2000; loading ...; fig 1b
Vogel S, Schäfer C, Hess S, Folz Donahue K, Nelles M, Minassian A, et al. The in vivo timeline of differentiation of engrafted human neural progenitor cells. Stem Cell Res. 2019;37:101429 pubmed publisher
  • immunohistochemistry; mouse; 1:200; loading ...; fig 1f
Dong J, Pan Y, Wu X, He L, Liu X, Feng D, et al. A neuronal molecular switch through cell-cell contact that regulates quiescent neural stem cells. Sci Adv. 2019;5:eaav4416 pubmed publisher
  • immunohistochemistry - free floating section; mouse; 1:500; loading ...; fig 1d
Shen M, Wang F, Li M, Sah N, Stockton M, Tidei J, et al. Reduced mitochondrial fusion and Huntingtin levels contribute to impaired dendritic maturation and behavioral deficits in Fmr1-mutant mice. Nat Neurosci. 2019;22:386-400 pubmed publisher
  • immunohistochemistry; human; 1:400; loading ...; fig s5a
Real R, Peter M, Trabalza A, Khan S, Smith M, Dopp J, et al. In vivo modeling of human neuron dynamics and Down syndrome. Science. 2018;362: pubmed publisher
  • immunocytochemistry; mouse; 1:1000; loading ...; fig 2a
Luo L, Guo K, Fan W, Lu Y, Chen L, Wang Y, et al. Niche astrocytes promote the survival, proliferation and neuronal differentiation of co-transplanted neural stem cells following ischemic stroke in rats. Exp Ther Med. 2017;13:645-650 pubmed publisher
  • western blot; mouse; 1:1000; loading ...; fig 6b
Mellott T, Huleatt O, Shade B, Pender S, Liu Y, Slack B, et al. Perinatal Choline Supplementation Reduces Amyloidosis and Increases Choline Acetyltransferase Expression in the Hippocampus of the APPswePS1dE9 Alzheimer's Disease Model Mice. PLoS ONE. 2017;12:e0170450 pubmed publisher
  • immunohistochemistry - free floating section; rat; 1:500; loading ...; tbl 2
Shepherd D, Tsai S, O Brien T, Farrer R, Kartje G. Anti-Nogo-A Immunotherapy Does Not Alter Hippocampal Neurogenesis after Stroke in Adult Rats. Front Neurosci. 2016;10:467 pubmed
  • immunohistochemistry - free floating section; mouse; 1:500; loading ...; fig 3i
Figueres Oñate M, López Mascaraque L. Adult Olfactory Bulb Interneuron Phenotypes Identified by Targeting Embryonic and Postnatal Neural Progenitors. Front Neurosci. 2016;10:194 pubmed publisher
  • western blot; mouse; 1:1000; loading ...; fig 3g
Currais A, Farrokhi C, Dargusch R, Goujon Svrzic M, Maher P. Dietary glycemic index modulates the behavioral and biochemical abnormalities associated with autism spectrum disorder. Mol Psychiatry. 2016;21:426-36 pubmed publisher
Docampo Seara A, Pereira Guldrís S, Sánchez Farías N, Mazan S, Rodriguez M, Candal E. Characterization of neurogenic niches in the telencephalon of juvenile and adult sharks. Brain Struct Funct. 2020;225:817-839 pubmed publisher
Poston R, Dunn C, Sarkar P, Saha R. Persistent 6-OH-BDE-47 exposure impairs functional neuronal maturation and alters expression of neurodevelopmentally-relevant chromatin remodelers. Environ Epigenet. 2018;4:dvx020 pubmed publisher
Lin Y, Chen C, Huang C, Nishimori K, Hsu K. Oxytocin stimulates hippocampal neurogenesis via oxytocin receptor expressed in CA3 pyramidal neurons. Nat Commun. 2017;8:537 pubmed publisher
Holmes D, Heine V. Simplified 3D protocol capable of generating early cortical neuroepithelium. Biol Open. 2017;6:402-406 pubmed publisher
Pang Y, Dai X, Roller A, Carter K, Paul I, Bhatt A, et al. Early Postnatal Lipopolysaccharide Exposure Leads to Enhanced Neurogenesis and Impaired Communicative Functions in Rats. PLoS ONE. 2016;11:e0164403 pubmed publisher
Klein B, Mrowetz H, Thalhamer J, Scheiblhofer S, Weiss R, Aigner L. Allergy Enhances Neurogenesis and Modulates Microglial Activation in the Hippocampus. Front Cell Neurosci. 2016;10:169 pubmed publisher
Sánchez Farías N, Candal E. Identification of Radial Glia Progenitors in the Developing and Adult Retina of Sharks. Front Neuroanat. 2016;10:65 pubmed publisher
Zhou K, Motamed S, Thouas G, Bernard C, Li D, Parkington H, et al. Graphene Functionalized Scaffolds Reduce the Inflammatory Response and Supports Endogenous Neuroblast Migration when Implanted in the Adult Brain. PLoS ONE. 2016;11:e0151589 pubmed publisher
Fernández López B, Romaus Sanjurjo D, Senra Martínez P, Anadón R, Barreiro Iglesias A, Rodicio M. Spatiotemporal Pattern of Doublecortin Expression in the Retina of the Sea Lamprey. Front Neuroanat. 2016;10:5 pubmed publisher
Nechiporuk T, MCGANN J, Mullendorff K, Hsieh J, Wurst W, Floss T, et al. The REST remodeling complex protects genomic integrity during embryonic neurogenesis. elife. 2016;5:e09584 pubmed publisher
Brøchner C, Møllgård K. SSEA-4 and YKL-40 positive progenitor subtypes in the subventricular zone of developing human neocortex. Glia. 2016;64:90-104 pubmed publisher
product information
SKU :
4604S
Product-Name :
Doublecortin Antibody
Size :
100 ul
Price-(USD) :
235 USD
Species-x-Reactivity :
H, M, R, Mk, Dm
Applications :
Flow cytometry
Product-Category :
Neuroscience
Shipping-Temp :
AMBIENT
Storage-Temp :
-20°C
Product-Type :
Polyclonal Antibody
MW :
45
Host :
Rabbit
Target :
doublecortin
Primary-Protein :
doublecortin
Alt-Names :
DBCN,DC,DCX,Doublin,LISX,Lis-X,Lissencephalin-X,Neuronal migration protein doublecortin,SCLH,XLIS,doublecortex,doublecortin
company information
Cell Signaling Technology
3 Trask Lane
Danvers, MA 01923
info@cellsignal.com
https://www.cellsignal.com
8776162355
headquarters: USA
Established in Beverly, MA in 1999, Cell Signaling Technology (CST) is a privately-owned company with over 400 employees worldwide. We are dedicated to providing innovative research tools that are used to help define mechanisms underlying cell function and disease. Since its inception, CST has become the world leader in the production of the highest quality activation-state and total protein antibodies utilized to expand knowledge of cell signaling pathways. Our mission is to deliver the world's highest quality research tools that accelerate progress in biological research and personalized medicine.