product summary
company name :
Cell Signaling Technology
product type :
antibody
product name :
TrkB (80E3) Rabbit mAb
catalog :
4603
clonality :
monoclonal
host :
rabbit
conjugate :
nonconjugated
clone name :
80E3
reactivity :
human, mouse, rat
application :
western blot
more info or order :
Cell Signaling Technology product webpage
citations: 14
Published Application/Species/Sample/DilutionReference
  • western blot; mouse; 1:1000; loading ...; fig 6e
Qian Q, Liu Q, Zhou D, Pan H, Liu Z, He F, et al. Brain-specific ablation of Efr3a promotes adult hippocampal neurogenesis via the brain-derived neurotrophic factor pathway. FASEB J. 2017;31:2104-2113 pubmed publisher
  • western blot; mouse; 1:250; loading ...; fig 2d
Shapiro L, Parsons R, Koleske A, Gourley S. Differential expression of cytoskeletal regulatory factors in the adolescent prefrontal cortex: Implications for cortical development. J Neurosci Res. 2017;95:1123-1143 pubmed publisher
  • western blot; mouse
Hong Y, Zhao T, Li X, Li S. Mutant Huntingtin Impairs BDNF Release from Astrocytes by Disrupting Conversion of Rab3a-GTP into Rab3a-GDP. J Neurosci. 2016;36:8790-801 pubmed publisher
  • western blot; mouse; 1:1000; fig 5d
Ren Q, Ma M, Ishima T, Morisseau C, Yang J, Wagner K, et al. Gene deficiency and pharmacological inhibition of soluble epoxide hydrolase confers resilience to repeated social defeat stress. Proc Natl Acad Sci U S A. 2016;113:E1944-52 pubmed publisher
  • western blot; mouse; 1:1000; loading ...; fig 1b
Yang P, Leu D, Ye K, Srinivasan C, Fike J, Huang T. Cognitive impairments following cranial irradiation can be mitigated by treatment with a tropomyosin receptor kinase B agonist. Exp Neurol. 2016;279:178-186 pubmed publisher
  • western blot; mouse; 1:1000; loading ...; fig 4c
Lin R, Chen J, Li X, Mao J, Wu Y, Zhuo P, et al. Electroacupuncture at the Baihui acupoint alleviates cognitive impairment and exerts neuroprotective effects by modulating the expression and processing of brain-derived neurotrophic factor in APP/PS1 transgenic mice. Mol Med Rep. 2016;13:1611-7 pubmed publisher
  • western blot; mouse; fig 6.c,d
Krishnan N, Krishnan K, Connors C, Choy M, Page R, Peti W, et al. PTP1B inhibition suggests a therapeutic strategy for Rett syndrome. J Clin Invest. 2015;125:3163-77 pubmed publisher
Chen W, Walwyn W, Ennes H, Kim H, McRoberts J, Marvizon J. BDNF released during neuropathic pain potentiates NMDA receptors in primary afferent terminals. Eur J Neurosci. 2014;39:1439-54 pubmed publisher
Todd D, Gowers I, Dowler S, Wall M, McAllister G, Fischer D, et al. A monoclonal antibody TrkB receptor agonist as a potential therapeutic for Huntington's disease. PLoS ONE. 2014;9:e87923 pubmed publisher
Yu Q, Chang Q, Liu X, Wang Y, Li H, Gong S, et al. Protection of spiral ganglion neurons from degeneration using small-molecule TrkB receptor agonists. J Neurosci. 2013;33:13042-52 pubmed publisher
Tian X, Hua F, Sandhu H, Chao D, Balboni G, Salvadori S, et al. Effect of ?-opioid receptor activation on BDNF-TrkB vs. TNF-? in the mouse cortex exposed to prolonged hypoxia. Int J Mol Sci. 2013;14:15959-76 pubmed publisher
Tian X, Guo J, Zhu M, Li M, Wu G, Xia Y. ?-Opioid receptor activation rescues the functional TrkB receptor and protects the brain from ischemia-reperfusion injury in the rat. PLoS ONE. 2013;8:e69252 pubmed publisher
Howe E, Cochrane D, Cittelly D, Richer J. miR-200c targets a NF-?B up-regulated TrkB/NTF3 autocrine signaling loop to enhance anoikis sensitivity in triple negative breast cancer. PLoS ONE. 2012;7:e49987 pubmed publisher
Kutiyanawalla A, Terry A, Pillai A. Cysteamine attenuates the decreases in TrkB protein levels and the anxiety/depression-like behaviors in mice induced by corticosterone treatment. PLoS ONE. 2011;6:e26153 pubmed publisher
product information
SKU :
4603S
Product-Name :
TrkB (80E3) Rabbit mAb
Size :
100 ul
Price-(USD) :
235 USD
Species-x-Reactivity :
H, M, R
Applications :
Western blot
Product-Category :
Neuroscience
Shipping-Temp :
AMBIENT
Storage-Temp :
-20°C
Product-Type :
Monoclonal Antibody
MW :
90, 140
Host :
Rabbit
Target :
TrkB
Primary-Protein :
TrkB
Alt-Names :
BDNF-tropomyosine receptor kinase B,BDNF/NT-3 growth factors receptor,GP145-TrkB,NTRK2,Neurotrophic tyrosine kinase receptor type 2,TRKB,Trk-B,TrkB tyrosine kinase,neurotrophic tyrosine kinase, receptor, type 2,tyrosine kinase receptor B
more info or order :
Cell Signaling Technology product webpage
company information
Cell Signaling Technology
3 Trask Lane
Danvers, MA 01923
info@cellsignal.com
www.cellsignal.com
8776162355
headquarters: USA
Established in Beverly, MA in 1999, Cell Signaling Technology (CST) is a privately-owned company with over 400 employees worldwide. We are dedicated to providing innovative research tools that are used to help define mechanisms underlying cell function and disease. Since its inception, CST has become the world leader in the production of the highest quality activation-state and total protein antibodies utilized to expand knowledge of cell signaling pathways. Our mission is to deliver the world's highest quality research tools that accelerate progress in biological research and personalized medicine.