product summary
company name :
Cell Signaling Technology
product type :
antibody
product name :
GATA-1 (D24E4) XP® Rabbit mAb
catalog :
4589
clonality :
monoclonal
host :
domestic rabbit
conjugate :
nonconjugated
clone name :
D24E4
reactivity :
human
application :
western blot, immunocytochemistry, immunoprecipitation, flow cytometry
citations: 20
Reference
Isfort I, Elges S, Cyra M, Berthold R, Renner M, Mechtersheimer G, et al. Prevalence of the Hippo Effectors YAP1/TAZ in Tumors of Soft Tissue and Bone. Sci Rep. 2019;9:19704 pubmed publisher
Hoj J, Mayro B, Pendergast A. A TAZ-AXL-ABL2 Feed-Forward Signaling Axis Promotes Lung Adenocarcinoma Brain Metastasis. Cell Rep. 2019;29:3421-3434.e8 pubmed publisher
Cayuso J, Xu Q, Addison M, Wilkinson D. Actomyosin regulation by Eph receptor signaling couples boundary cell formation to border sharpness. elife. 2019;8: pubmed publisher
di Martino E, Alder O, Hurst C, Knowles M. ETV5 links the FGFR3 and Hippo signalling pathways in bladder cancer. Sci Rep. 2019;9:5740 pubmed publisher
Komatsu N, Kajiya M, Motoike S, Takewaki M, Horikoshi S, Iwata T, et al. Type I collagen deposition via osteoinduction ameliorates YAP/TAZ activity in 3D floating culture clumps of mesenchymal stem cell/extracellular matrix complexes. Stem Cell Res Ther. 2018;9:342 pubmed publisher
Lavado A, Park J, Pare J, Finkelstein D, Pan H, Xu B, et al. The Hippo Pathway Prevents YAP/TAZ-Driven Hypertranscription and Controls Neural Progenitor Number. Dev Cell. 2018;47:576-591.e8 pubmed publisher
Gill M, Christova T, Zhang Y, Gregorieff A, Zhang L, Narimatsu M, et al. A feed forward loop enforces YAP/TAZ signaling during tumorigenesis. Nat Commun. 2018;9:3510 pubmed publisher
Gui Y, Li J, Lu Q, Feng Y, Wang M, He W, et al. Yap/Taz mediates mTORC2-stimulated fibroblast activation and kidney fibrosis. J Biol Chem. 2018;293:16364-16375 pubmed publisher
Er E, Valiente M, Ganesh K, Zou Y, Agrawal S, Hu J, et al. Pericyte-like spreading by disseminated cancer cells activates YAP and MRTF for metastatic colonization. Nat Cell Biol. 2018;20:966-978 pubmed publisher
Pan J, Xiong L, Zhao K, Zeng P, Wang B, Tang F, et al. YAP promotes osteogenesis and suppresses adipogenic differentiation by regulating β-catenin signaling. Bone Res. 2018;6:18 pubmed publisher
Lai J, Collins M, Uribe V, Jiménez Amilburu V, Günther S, Maischein H, et al. The Hippo pathway effector Wwtr1 regulates cardiac wall maturation in zebrafish. Development. 2018;145: pubmed publisher
Han S, Pang M, Nelson C. Substratum stiffness tunes proliferation downstream of Wnt3a in part by regulating integrin-linked kinase and frizzled-1. J Cell Sci. 2018;131: pubmed publisher
Xiao Z, Baudry J, Cao L, Huang J, Chen H, Yates C, et al. Polycystin-1 interacts with TAZ to stimulate osteoblastogenesis and inhibit adipogenesis. J Clin Invest. 2018;128:157-174 pubmed publisher
Toyama T, Looney A, Baker B, Stawski L, Haines P, Simms R, et al. Therapeutic Targeting of TAZ and YAP by Dimethyl Fumarate in Systemic Sclerosis Fibrosis. J Invest Dermatol. 2018;138:78-88 pubmed publisher
Dieffenbach P, Haeger C, Coronata A, Choi K, Varelas X, Tschumperlin D, et al. Arterial stiffness induces remodeling phenotypes in pulmonary artery smooth muscle cells via YAP/TAZ-mediated repression of cyclooxygenase-2. Am J Physiol Lung Cell Mol Physiol. 2017;313:L628-L647 pubmed publisher
Shanzer M, Adler J, Ricardo Lax I, Reuven N, Shaul Y. The nonreceptor tyrosine kinase c-Src attenuates SCF(β-TrCP) E3-ligase activity abrogating Taz proteasomal degradation. Proc Natl Acad Sci U S A. 2017;114:1678-1683 pubmed publisher
Mori S, Takeuchi T, Ishii Y, Yugawa T, Kiyono T, Nishina H, et al. Human Papillomavirus 16 E6 Upregulates APOBEC3B via the TEAD Transcription Factor. J Virol. 2017;91: pubmed publisher
Andl T, Le Bras G, Richards N, Allison G, Loomans H, Washington M, et al. Concerted loss of TGFβ-mediated proliferation control and E-cadherin disrupts epithelial homeostasis and causes oral squamous cell carcinoma. Carcinogenesis. 2014;35:2602-10 pubmed publisher
Bartucci M, Dattilo R, Moriconi C, Pagliuca A, Mottolese M, Federici G, et al. TAZ is required for metastatic activity and chemoresistance of breast cancer stem cells. Oncogene. 2015;34:681-90 pubmed publisher
Ahluwalia M, Donovan H, Singh N, Butcher L, Erusalimsky J. Anagrelide represses GATA-1 and FOG-1 expression without interfering with thrombopoietin receptor signal transduction. J Thromb Haemost. 2010;8:2252-61 pubmed publisher
product information
SKU :
4589S
Product-Name :
GATA-1 (D24E4) XP® Rabbit mAb
Size :
100 ul
Price-(USD) :
260 USD
Species-x-Reactivity :
H
Applications :
Flow cytometry
Product-Category :
Developmental Biology
Shipping-Temp :
AMBIENT
Storage-Temp :
-20°C
Product-Type :
Monoclonal Antibody
MW :
43
Host :
Rabbit
Target :
GATA1
Primary-Protein :
GATA1
Alt-Names :
ERYF1,Erythroid transcription factor,GATA binding protein 1 (globin transcription factor 1),GATA-1,GATA-binding factor 1,GATA1,GF-1,GF1,NF-E1 DNA-binding protein,NFE1,XLTT,erythroid transcription factor 1,globin transcription factor 1,transcription factor GATA1
company information
Cell Signaling Technology
3 Trask Lane
Danvers, MA 01923
info@cellsignal.com
https://www.cellsignal.com
8776162355
headquarters: USA
Established in Beverly, MA in 1999, Cell Signaling Technology (CST) is a privately-owned company with over 400 employees worldwide. We are dedicated to providing innovative research tools that are used to help define mechanisms underlying cell function and disease. Since its inception, CST has become the world leader in the production of the highest quality activation-state and total protein antibodies utilized to expand knowledge of cell signaling pathways. Our mission is to deliver the world's highest quality research tools that accelerate progress in biological research and personalized medicine.