product summary
company name :
Cell Signaling Technology
product type :
antibody
product name :
Cool2/αPix (C23D2) Rabbit mAb
catalog :
4573
clonality :
monoclonal
host :
rabbit
conjugate :
nonconjugated
clone name :
C23D2
reactivity :
human, mouse, rat, dog
application :
western blot, immunocytochemistry
citations: 6
Published Application/Species/Sample/DilutionReference
  • western blot; human; fig 5e
Nagy Z, Wynne K, von Kriegsheim A, Gambaryan S, Smolenski A. Cyclic Nucleotide-dependent Protein Kinases Target ARHGAP17 and ARHGEF6 Complexes in Platelets. J Biol Chem. 2015;290:29974-83 pubmed publisher
  • immunocytochemistry; mouse; 1:400; fig 8
  • western blot; mouse; 1:1000; fig 8
Yan Y, Tsukamoto O, Nakano A, Kato H, Kioka H, Ito N, et al. Augmented AMPK activity inhibits cell migration by phosphorylating the novel substrate Pdlim5. Nat Commun. 2015;6:6137 pubmed publisher
Fujiki K, Inamura H, Miyayama T, Matsuoka M. Involvement of Notch1 signaling in malignant progression of A549 cells subjected to prolonged cadmium exposure. J Biol Chem. 2017;292:7942-7953 pubmed publisher
Fujiki K, Inamura H, Matsuoka M. Detrimental effects of Notch1 signaling activated by cadmium in renal proximal tubular epithelial cells. Cell Death Dis. 2014;5:e1378 pubmed publisher
Fiaschetti G, Schroeder C, Castelletti D, Arcaro A, Westermann F, Baumgartner M, et al. NOTCH ligands JAG1 and JAG2 as critical pro-survival factors in childhood medulloblastoma. Acta Neuropathol Commun. 2014;2:39 pubmed publisher
Daubon T, Buccione R, G not E. The Aarskog-Scott syndrome protein Fgd1 regulates podosome formation and extracellular matrix remodeling in transforming growth factor ?-stimulated aortic endothelial cells. Mol Cell Biol. 2011;31:4430-41 pubmed publisher
product information
SKU :
4573S
Product-Name :
Cool2/αPix (C23D2) Rabbit mAb
Size :
100 ul
Price-(USD) :
235 USD
Species-x-Reactivity :
H, M, (R, Dg)
Applications :
Immunofluorescence (Immunocytochemistry)
Product-Category :
Cytoskeletal Signaling
Shipping-Temp :
AMBIENT
Storage-Temp :
-20°C
Product-Type :
Monoclonal Antibody
MW :
87
Host :
Rabbit
Target :
ArhGEF6
Primary-Protein :
ARHGEF6
Alt-Names :
ARHG6,ARHGEF6,Alpha-Pix,COOL-2,COOL2,KIAA0006,MRX46,PAK-interacting exchange factor alpha,PAK-interacting exchange factor, alpha,PIXA,Rac/Cdc42 guanine exchange factor (GEF) 6,Rac/Cdc42 guanine nucleotide exchange factor (GEF) 6,Rac/Cdc42 guanine nucleotide exchange factor 6,Rho guanine nucleotide exchange factor 6,alphaPIX,mental retardation, X-linked 46
company information
Cell Signaling Technology
3 Trask Lane
Danvers, MA 01923
info@cellsignal.com
https://www.cellsignal.com
8776162355
headquarters: USA
Established in Beverly, MA in 1999, Cell Signaling Technology (CST) is a privately-owned company with over 400 employees worldwide. We are dedicated to providing innovative research tools that are used to help define mechanisms underlying cell function and disease. Since its inception, CST has become the world leader in the production of the highest quality activation-state and total protein antibodies utilized to expand knowledge of cell signaling pathways. Our mission is to deliver the world's highest quality research tools that accelerate progress in biological research and personalized medicine.