product summary
company name :
Cell Signaling Technology
product type :
antibody
product name :
Mcl-1 Antibody
catalog :
4572S
quantity :
100 ul
price :
235 USD
clonality :
polyclonal
host :
rabbit
reactivity :
human
application :
western blot
citations: 10
Published Application/Species/DilutionReference
  • western blot; human; 1:1000; fig 3
Kushwaha D, O'Leary C, Cron K, Deraska P, Zhu K, D'ANDREA A, et al. USP9X inhibition promotes radiation-induced apoptosis in non-small cell lung cancer cells expressing mid-to-high MCL1. Cancer Biol Ther. 2015;16:392-401 pubmed publisher
  • western blot; human
Cazanave S, Wang X, Zhou H, Rahmani M, Grant S, Durrant D, et al. Degradation of Keap1 activates BH3-only proteins Bim and PUMA during hepatocyte lipoapoptosis. Cell Death Differ. 2014;21:1303-12 pubmed publisher
Frederick D, Salas Fragomeni R, Schalck A, Ferreiro-Neira I, Hoff T, Cooper Z, et al. Clinical profiling of BCL-2 family members in the setting of BRAF inhibition offers a rationale for targeting de novo resistance using BH3 mimetics. PLoS ONE. 2014;9:e101286 pubmed publisher
Wu Y, Crawford M, Mao Y, Lee R, Davis I, Elton T, et al. Therapeutic Delivery of MicroRNA-29b by Cationic Lipoplexes for Lung Cancer. Mol Ther Nucleic Acids. 2013;2:e84 pubmed publisher
Guo X, Dong Y, Yin S, Zhao C, Huo Y, Fan L, et al. Patulin induces pro-survival functions via autophagy inhibition and p62 accumulation. Cell Death Dis. 2013;4:e822 pubmed publisher
Roccaro A, Leleu X, Sacco A, Jia X, Melhem M, Moreau A, et al. Dual targeting of the proteasome regulates survival and homing in Waldenstrom macroglobulinemia. Blood. 2008;111:4752-63 pubmed publisher
Xiang X, Phung Y, Feng M, Nagashima K, Zhang J, Broaddus V, et al. The development and characterization of a human mesothelioma in vitro 3D model to investigate immunotoxin therapy. PLoS ONE. 2011;6:e14640 pubmed publisher
Ocio E, Maiso P, Chen X, Garayoa M, Alvarez-Fernández S, San-Segundo L, et al. Zalypsis: a novel marine-derived compound with potent antimyeloma activity that reveals high sensitivity of malignant plasma cells to DNA double-strand breaks. Blood. 2009;113:3781-91 pubmed publisher
Kashkar H, Deggerich A, Seeger J, Yazdanpanah B, Wiegmann K, Haubert D, et al. NF-kappaB-independent down-regulation of XIAP by bortezomib sensitizes HL B cells against cytotoxic drugs. Blood. 2007;109:3982-8 pubmed
Roccaro A, Leleu X, Sacco A, Moreau A, Hatjiharissi E, Jia X, et al. Resveratrol exerts antiproliferative activity and induces apoptosis in Waldenström's macroglobulinemia. Clin Cancer Res. 2008;14:1849-58 pubmed publisher
product information
SKU :
4572S
Product-Name :
Mcl-1 Antibody
Size :
100 ul
Price-(USD) :
235 USD
Species-x-Reactivity :
H
Applications :
Western blot
Product-Category :
Apoptosis
Shipping-Temp :
AMBIENT
Storage-Temp :
-20°C
Product-Type :
Polyclonal Antibody
MW :
40
Host :
Rabbit
Target :
MCL1
Primary-Protein :
MCL1
Alt-Names :
BCL2L3,Bcl-2-like protein 3,Bcl-2-related protein EAT/mcl1,Bcl2-L-3,EAT,Induced myeloid leukemia cell differentiation protein Mcl-1,MCL1,MCL1L,MCL1S,MGC104264,MGC1839,Mcl-1,TM,mcl1/EAT,myeloid cell leukemia ES,myeloid cell leukemia sequence 1 (BCL2-related),myeloid cell leukemia sequence 1, isoform 1
company information
Cell Signaling Technology
3 Trask Lane
Danvers, MA 01923
info@cellsignal.com
www.cellsignal.com
8776162355
headquarters: USA
Established in Beverly, MA in 1999, Cell Signaling Technology (CST) is a privately-owned company with over 400 employees worldwide. We are dedicated to providing innovative research tools that are used to help define mechanisms underlying cell function and disease. Since its inception, CST has become the world leader in the production of the highest quality activation-state and total protein antibodies utilized to expand knowledge of cell signaling pathways. Our mission is to deliver the world's highest quality research tools that accelerate progress in biological research and personalized medicine.