product summary
company name :
Cell Signaling Technology
product type :
antibody
product name :
Axl (C44G1) Rabbit mAb
catalog :
4566
clonality :
monoclonal
host :
rabbit
conjugate :
nonconjugated
clone name :
C44G1
reactivity :
human
application :
western blot, immunoprecipitation, flow cytometry, other
more info or order :
Cell Signaling Technology product webpage
citations: 5
Published Application/Species/Sample/DilutionReference
  • western blot; human; fig 3
van der Mijn J, Broxterman H, Knol J, Piersma S, de Haas R, Dekker H, et al. Sunitinib activates Axl signaling in renal cell cancer. Int J Cancer. 2016;138:3002-10 pubmed publisher
  • other; human; fig 2
  • immunoprecipitation; human; fig 1
Debruyne D, Bhatnagar N, Sharma B, Luther W, Moore N, Cheung N, et al. ALK inhibitor resistance in ALK(F1174L)-driven neuroblastoma is associated with AXL activation and induction of EMT. Oncogene. 2016;35:3681-91 pubmed publisher
  • western blot; human; fig 5
Azzolin L, Panciera T, Soligo S, Enzo E, Bicciato S, Dupont S, et al. YAP/TAZ incorporation in the ?-catenin destruction complex orchestrates the Wnt response. Cell. 2014;158:157-70 pubmed publisher
Mori M, Kaneko N, Ueno Y, Yamada M, Tanaka R, Saito R, et al. Gilteritinib, a FLT3/AXL inhibitor, shows antileukemic activity in mouse models of FLT3 mutated acute myeloid leukemia. Invest New Drugs. 2017;35:556-565 pubmed publisher
Kurokawa M, Ise N, Omi K, Goishi K, Higashiyama S. Cisplatin influences acquisition of resistance to molecular-targeted agents through epithelial-mesenchymal transition-like changes. Cancer Sci. 2013;104:904-11 pubmed publisher
product information
SKU :
4566S
Product-Name :
Axl (C44G1) Rabbit mAb
Size :
100 ul
Price-(USD) :
235 USD
Species-x-Reactivity :
H, Mk
Applications :
Flow cytometry
Product-Category :
RTK
Shipping-Temp :
AMBIENT
Storage-Temp :
-20°C
Product-Type :
Monoclonal Antibody
MW :
138
Host :
Rabbit
Target :
Axl
Primary-Protein :
Axl
Alt-Names :
AXL,AXL oncogene,AXL receptor tyrosine kinase,AXL transforming sequence/gene,JTK11,Tyrosine-protein kinase receptor UFO,UFO,oncogene AXL
more info or order :
Cell Signaling Technology product webpage
company information
Cell Signaling Technology
3 Trask Lane
Danvers, MA 01923
info@cellsignal.com
https://www.cellsignal.com
8776162355
headquarters: USA
Established in Beverly, MA in 1999, Cell Signaling Technology (CST) is a privately-owned company with over 400 employees worldwide. We are dedicated to providing innovative research tools that are used to help define mechanisms underlying cell function and disease. Since its inception, CST has become the world leader in the production of the highest quality activation-state and total protein antibodies utilized to expand knowledge of cell signaling pathways. Our mission is to deliver the world's highest quality research tools that accelerate progress in biological research and personalized medicine.