product summary
company name :
Cell Signaling Technology
product type :
antibody
product name :
Phospho-cdc2 (Tyr15) (10A11) Rabbit mAb
catalog :
4539S
quantity :
100 ul
price :
274 USD
clonality :
monoclonal
host :
rabbit
antigen modification :
phosphorylated
clone name :
10A11
reactivity :
human, mouse, rat
application :
western blot, immunocytochemistry, immunoprecipitation, flow cytometry
more info or order :
Cell Signaling Technology product webpage
citations: 9
Published Application/Species/DilutionReference
  • western blot; human; 1:1000; fig st1
Treindl F, Ruprecht B, Beiter Y, Schultz S, Döttinger A, Staebler A, et al. A bead-based western for high-throughput cellular signal transduction analyses. Nat Commun. 2016;7:12852 pubmed publisher
  • western blot; human; 1:1000; fig s2
Wang J, Hu K, Guo J, Cheng F, Lv J, Jiang W, et al. Suppression of KRas-mutant cancer through the combined inhibition of KRAS with PLK1 and ROCK. Nat Commun. 2016;7:11363 pubmed publisher
  • western blot; human
Xue L, Furusawa Y, Okayasu R, Miura M, Cui X, Liu C, et al. The complexity of DNA double strand break is a crucial factor for activating ATR signaling pathway for G2/M checkpoint regulation regardless of ATM function. DNA Repair (Amst). 2015;25:72-83 pubmed publisher
  • western blot; human; fig 2d
Fukumoto Y, Morii M, Miura T, Kubota S, Ishibashi K, Honda T, et al. Src family kinases promote silencing of ATR-Chk1 signaling in termination of DNA damage checkpoint. J Biol Chem. 2014;289:12313-29 pubmed publisher
  • western blot; human
Hasegawa H, Ishibashi K, Kubota S, Yamaguchi C, Yuki R, Nakajo H, et al. Cdk1-mediated phosphorylation of human ATF7 at Thr-51 and Thr-53 promotes cell-cycle progression into M phase. PLoS ONE. 2014;9:e116048 pubmed publisher
  • western blot; mouse; fig 4
Adeyemi R, Pintel D. Parvovirus-induced depletion of cyclin B1 prevents mitotic entry of infected cells. PLoS Pathog. 2014;10:e1003891 pubmed publisher
  • western blot; human
Garimella S, Rocca A, Lipkowitz S. WEE1 inhibition sensitizes basal breast cancer cells to TRAIL-induced apoptosis. Mol Cancer Res. 2012;10:75-85 pubmed publisher
Van de Wouwer M, Couzinié C, Serrano-Palero M, Gonzalez-Fernandez O, Galmés-Varela C, Menéndez-Antolí P, et al. Activation of the BRCA1/Chk1/p53/p21(Cip1/Waf1) pathway by nitric oxide and cell cycle arrest in human neuroblastoma NB69 cells. Nitric Oxide. 2012;26:182-91 pubmed publisher
Behbehani G, Bendall S, Clutter M, Fantl W, Nolan G. Single-cell mass cytometry adapted to measurements of the cell cycle. Cytometry A. 2012;81:552-66 pubmed publisher
product information
SKU :
4539S
Product-Name :
Phospho-cdc2 (Tyr15) (10A11) Rabbit mAb
Size :
100 ul
Price-(USD) :
274 USD
Species-x-Reactivity :
H, M, R, Mk
Applications :
Flow cytometry
Product-Category :
Cell Cycle / Checkpoint Control
Shipping-Temp :
COLD
Storage-Temp :
-20°C
Product-Type :
Monoclonal Antibody
MW :
34
Host :
Rabbit
Target :
Cdc2 (Tyr15) phosphate
Primary-Protein :
CDK1
Alt-Names :
CDC2,CDC28A,CDK1,Cell division control protein 2 homolog,Cyclin-dependent kinase 1,DKFZp686L20222,MGC111195,P34CDC2,cell cycle controller CDC2,cell division cycle 2,cell division cycle 2, G1 to S and G2 to M,p34 protein kinase
more info or order :
Cell Signaling Technology product webpage
company information
Cell Signaling Technology
3 Trask Lane
Danvers, MA 01923
info@cellsignal.com
www.cellsignal.com
8776162355
headquarters: USA
Established in Beverly, MA in 1999, Cell Signaling Technology (CST) is a privately-owned company with over 400 employees worldwide. We are dedicated to providing innovative research tools that are used to help define mechanisms underlying cell function and disease. Since its inception, CST has become the world leader in the production of the highest quality activation-state and total protein antibodies utilized to expand knowledge of cell signaling pathways. Our mission is to deliver the world's highest quality research tools that accelerate progress in biological research and personalized medicine.