product summary
company name :
Cell Signaling Technology
product type :
antibody
product name :
Phospho-TAK1 (Thr184/187) Antibody
catalog :
4531
clonality :
polyclonal
host :
rabbit
conjugate :
nonconjugated
antigen modification :
phosphorylated
reactivity :
human, mouse, rat, cow
application :
western blot
more info or order :
Cell Signaling Technology product webpage
citations: 13
Published Application/Species/Sample/DilutionReference
  • western blot; mouse; loading ...; fig 2d
Cong Q, Jia H, Li P, Qiu S, Yeh J, Wang Y, et al. p38? MAPK regulates proliferation and differentiation of osteoclast progenitors and bone remodeling in an aging-dependent manner. Sci Rep. 2017;7:45964 pubmed publisher
  • western blot; mouse; loading ...; fig EV4c
Hammers D, Merscham Banda M, Hsiao J, ENGST S, Hartman J, Sweeney H. Supraphysiological levels of GDF11 induce striated muscle atrophy. EMBO Mol Med. 2017;9:531-544 pubmed publisher
  • western blot; human; 1:1000; fig 6a
Huang T, Alvarez A, Pangeni R, Horbinski C, Lu S, Kim S, et al. A regulatory circuit of miR-125b/miR-20b and Wnt signalling controls glioblastoma phenotypes through FZD6-modulated pathways. Nat Commun. 2016;7:12885 pubmed publisher
  • western blot; mouse; fig 1
  • western blot; human; fig s1
Chen I, Hsu P, Hsu W, Chen N, Tseng P. Polyubiquitination of Transforming Growth Factor β-activated Kinase 1 (TAK1) at Lysine 562 Residue Regulates TLR4-mediated JNK and p38 MAPK Activation. Sci Rep. 2015;5:12300 pubmed publisher
  • western blot; mouse; 1:1000
Yu B, Chang J, Liu Y, Li J, Kevork K, Al Hezaimi K, et al. Wnt4 signaling prevents skeletal aging and inflammation by inhibiting nuclear factor-?B. Nat Med. 2014;20:1009-17 pubmed publisher
  • western blot; human
Zhan Z, Xie X, Cao H, Zhou X, Zhang X, Fan H, et al. Autophagy facilitates TLR4- and TLR3-triggered migration and invasion of lung cancer cells through the promotion of TRAF6 ubiquitination. Autophagy. 2014;10:257-68 pubmed publisher
  • western blot; human
Son J, Varadarajan S, Bratton S. TRAIL-activated stress kinases suppress apoptosis through transcriptional upregulation of MCL-1. Cell Death Differ. 2010;17:1288-301 pubmed publisher
Li Z, Chen Z, Zhang T, Wei C, Shi W. TGF-? and NF-?B signaling pathway crosstalk potentiates corneal epithelial senescence through an RNA stress response. Aging (Albany NY). 2016;8:2337-2354 pubmed publisher
Onodera Y, Teramura T, Takehara T, Shigi K, Fukuda K. Reactive oxygen species induce Cox-2 expression via TAK1 activation in synovial fibroblast cells. FEBS Open Bio. 2015;5:492-501 pubmed publisher
Dharmarajan S, Gurel Z, Wang S, Sorenson C, Sheibani N, Belecky Adams T. Bone morphogenetic protein 7 regulates reactive gliosis in retinal astrocytes and Müller glia. Mol Vis. 2014;20:1085-108 pubmed
Yan J, Zhang H, Yin Y, Li J, Tang Y, Purkayastha S, et al. Obesity- and aging-induced excess of central transforming growth factor-? potentiates diabetic development via an RNA stress response. Nat Med. 2014;20:1001-8 pubmed publisher
Morales Alamo D, Ponce Gonzalez J, Guadalupe Grau A, Rodríguez García L, Santana A, Cusso M, et al. Increased oxidative stress and anaerobic energy release, but blunted Thr172-AMPK? phosphorylation, in response to sprint exercise in severe acute hypoxia in humans. J Appl Physiol (1985). 2012;113:917-28 pubmed publisher
Ahmed N, Zeng M, Sinha I, Polin L, Wei W, Rathinam C, et al. The E3 ligase Itch and deubiquitinase Cyld act together to regulate Tak1 and inflammation. Nat Immunol. 2011;12:1176-83 pubmed publisher
product information
SKU :
4531S
Product-Name :
Phospho-TAK1 (Thr184/187) Antibody
Size :
100 ul
Price-(USD) :
274 USD
Species-x-Reactivity :
H, (M, R, C, X, Z, B)
Applications :
Western blot
Product-Category :
MAP Kinase Signaling
Shipping-Temp :
AMBIENT
Storage-Temp :
-20°C
Product-Type :
Polyclonal Antibody
MW :
82
Host :
Rabbit
Target :
TAK1 (Thr184/Thr187) phosphate
Primary-Protein :
TAK1
Alt-Names :
M3K7,MAP3K7,MEKK7,Mitogen-activated protein kinase kinase kinase 7,TAK1,TGF-beta activated kinase 1,TGF-beta-activated kinase 1,TGF1a,Transforming growth factor-beta-activated kinase 1
more info or order :
Cell Signaling Technology product webpage
company information
Cell Signaling Technology
3 Trask Lane
Danvers, MA 01923
info@cellsignal.com
www.cellsignal.com
8776162355
headquarters: USA
Established in Beverly, MA in 1999, Cell Signaling Technology (CST) is a privately-owned company with over 400 employees worldwide. We are dedicated to providing innovative research tools that are used to help define mechanisms underlying cell function and disease. Since its inception, CST has become the world leader in the production of the highest quality activation-state and total protein antibodies utilized to expand knowledge of cell signaling pathways. Our mission is to deliver the world's highest quality research tools that accelerate progress in biological research and personalized medicine.