product summary
company name :
Cell Signaling Technology
product type :
antibody
product name :
Notch2 (D67C8) XP® Rabbit mAb
catalog :
4530
clonality :
monoclonal
host :
domestic rabbit
conjugate :
nonconjugated
clone name :
D67C8
reactivity :
human, mouse, rat
application :
western blot, immunocytochemistry, immunoprecipitation, immunohistochemistry - paraffin section, immunohistochemistry - frozen section, immunohistochemistry knockout validation
citations: 10
Published Application/Species/Sample/DilutionReference
  • immunohistochemistry knockout validation; mouse; 1:2000; loading ...; fig ed7c
  • immunohistochemistry - frozen section; mouse; 1:2000; loading ...; fig 2b
Pardo Saganta A, Tata P, Law B, Saez B, Chow R, Prabhu M, et al. Parent stem cells can serve as niches for their daughter cells. Nature. 2015;523:597-601 pubmed publisher
  • western blot; human; loading ...; fig s1a, s1b
Lin Q, Chen X, Meng F, Ogawa K, Li M, Song R, et al. ASPH-notch Axis guided Exosomal delivery of Prometastatic Secretome renders breast Cancer multi-organ metastasis. Mol Cancer. 2019;18:156 pubmed publisher
  • immunohistochemistry - paraffin section; human
  • western blot; human; 1:1000
Gomi K, Arbelaez V, Crystal R, Walters M. Activation of NOTCH1 or NOTCH3 signaling skews human airway basal cell differentiation toward a secretory pathway. PLoS ONE. 2015;10:e0116507 pubmed publisher
  • western blot; human; fig 1
Dong X, Lin Q, Aihara A, Li Y, Huang C, Chung W, et al. Aspartate β-Hydroxylase expression promotes a malignant pancreatic cellular phenotype. Oncotarget. 2015;6:1231-48 pubmed
  • western blot; human
Subramani R, Lopez Valdez R, Arumugam A, Nandy S, Boopalan T, Lakshmanaswamy R. Targeting insulin-like growth factor 1 receptor inhibits pancreatic cancer growth and metastasis. PLoS ONE. 2014;9:e97016 pubmed publisher
  • western blot; human
Singh A, Zapata M, Choi Y, Yoon S. GSI promotes vincristine-induced apoptosis by enhancing multi-polar spindle formation. Cell Cycle. 2014;13:157-66 pubmed publisher
Pardo Saganta A, Law B, Tata P, Villoria J, Saez B, Mou H, et al. Injury induces direct lineage segregation of functionally distinct airway basal stem/progenitor cell subpopulations. Cell Stem Cell. 2015;16:184-97 pubmed publisher
Danza G, Di Serio C, Ambrosio M, Sturli N, Lonetto G, Rosati F, et al. Notch3 is activated by chronic hypoxia and contributes to the progression of human prostate cancer. Int J Cancer. 2013;133:2577-86 pubmed publisher
Sakamoto K, Fujii T, Kawachi H, Miki Y, Omura K, Morita K, et al. Reduction of NOTCH1 expression pertains to maturation abnormalities of keratinocytes in squamous neoplasms. Lab Invest. 2012;92:688-702 pubmed publisher
Danza G, Di Serio C, Rosati F, Lonetto G, Sturli N, Kacer D, et al. Notch signaling modulates hypoxia-induced neuroendocrine differentiation of human prostate cancer cells. Mol Cancer Res. 2012;10:230-8 pubmed publisher
product information
SKU :
4530P
Product-Name :
Notch2 (D67C8) XP® Rabbit mAb
Size :
40 ul
Price-(USD) :
135 USD
Species-x-Reactivity :
H, R
Applications :
Immunofluorescence (Immunocytochemistry)
Product-Category :
Developmental Biology
Shipping-Temp :
AMBIENT
Storage-Temp :
-20°C
Product-Type :
Monoclonal Antibody
MW :
110, 300
Host :
Rabbit
Target :
Notch2
Primary-Protein :
Notch 2
Alt-Names :
AGS2,NOTC2,NOTCH2,Neurogenic locus notch homolog protein 2,Notch 2,Notch 2 extracellular truncation,Notch 2 intracellular domain,Notch homolog 2 (Drosophila),hN2
company information
Cell Signaling Technology
3 Trask Lane
Danvers, MA 01923
info@cellsignal.com
https://www.cellsignal.com
8776162355
headquarters: USA
Established in Beverly, MA in 1999, Cell Signaling Technology (CST) is a privately-owned company with over 400 employees worldwide. We are dedicated to providing innovative research tools that are used to help define mechanisms underlying cell function and disease. Since its inception, CST has become the world leader in the production of the highest quality activation-state and total protein antibodies utilized to expand knowledge of cell signaling pathways. Our mission is to deliver the world's highest quality research tools that accelerate progress in biological research and personalized medicine.