mTOR (L27D4) Mouse mAb | Cell Signaling Technology 4517 product information

product summary

company name :

Cell Signaling Technology

product type :

antibody

product name :

mTOR (L27D4) Mouse mAb

catalog :

4517

clonality :

monoclonal

host :

mouse

conjugate :

nonconjugated

clone name :

L27D4

reactivity :

human, mouse, brown rat

application :

western blot

more info or order :

Cell Signaling Technology product webpage

citations: 15

Published Application/Species/Sample/Dilution	Reference
western blot; mouse; loading ...; fig 3b	Uddin G, Zhang L, Shah S, Fukushima A, Wagg C, Gopal K, et al. Impaired branched chain amino acid oxidation contributes to cardiac insulin resistance in heart failure. Cardiovasc Diabetol. 2019;18:86 pubmed publisher
western blot; brown rat; loading ...; fig 10c	Gasparotto J, Girardi C, Somensi N, Ribeiro C, Moreira J, Michels M, et al. Receptor for advanced glycation end products mediates sepsis-triggered amyloid-β accumulation, Tau phosphorylation, and cognitive impairment. J Biol Chem. 2018;293:226-244 pubmed publisher
western blot; mouse; 1:1000; loading ...; fig 9e	Hussain R, Macklin W. Integrin-Linked Kinase (ILK) Deletion Disrupts Oligodendrocyte Development by Altering Cell Cycle. J Neurosci. 2017;37:397-412 pubmed publisher
western blot; mouse; fig 7	Verbist K, Guy C, Milasta S, Liedmann S, Kaminski M, Wang R, et al. Metabolic maintenance of cell asymmetry following division in activated T lymphocytes. Nature. 2016;532:389-93 pubmed publisher
western blot; human; fig 6	Wang Y, Xu Q, Sack L, Kang C, Elledge S. A gain-of-function senescence bypass screen identifies the homeobox transcription factor DLX2 as a regulator of ATM-p53 signaling. Genes Dev. 2016;30:293-306 pubmed publisher
western blot; human; 1:1000; tbl 1	Oudart J, DouÃ© M, Vautrin A, Brassart B, Sellier C, Dupont Deshorgue A, et al. The anti-tumor NC1 domain of collagen XIX inhibits the FAK/ PI3K/Akt/mTOR signaling pathway through Î±vÎ²3 integrin interaction. Oncotarget. 2016;7:1516-28 pubmed publisher
western blot; human; fig 1	Yi Y, Kang H, Bae E, Oh S, Seong Y, Bae I. Î²-TrCP1 degradation is a novel action mechanism of PI3K/mTOR inhibitors in triple-negative breast cancer cells. Exp Mol Med. 2015;47:e143 pubmed publisher
western blot; brown rat western blot; mouse	Jaishy B, Zhang Q, Chung H, Riehle C, Soto J, Jenkins S, et al. Lipid-induced NOX2 activation inhibits autophagic flux by impairing lysosomal enzyme activity. J Lipid Res. 2015;56:546-61 pubmed publisher
western blot; human; 1:1000; fig 3	Ambrosi G, Ghezzi C, Sepe S, Milanese C, Payan Gomez C, Bombardieri C, et al. Bioenergetic and proteolytic defects in fibroblasts from patients with sporadic Parkinson's disease. Biochim Biophys Acta. 2014;1842:1385-94 pubmed publisher
western blot; human	Subramani R, Lopez Valdez R, Arumugam A, Nandy S, Boopalan T, Lakshmanaswamy R. Targeting insulin-like growth factor 1 receptor inhibits pancreatic cancer growth and metastasis. PLoS ONE. 2014;9:e97016 pubmed publisher
western blot; human; loading ...; fig 5e	Xia Q, Cai Y, Peng R, Wu G, Shi Y, Jiang W. The CDK1 inhibitor RO3306 improves the response of BRCA-pro?cient breast cancer cells to PARP inhibition. Int J Oncol. 2014;44:735-44 pubmed publisher
	Kazyken D, Kaz Y, Kiyan V, Zhylkibayev A, Chen C, Agarwal N, et al. The nuclear import of ribosomal proteins is regulated by mTOR. Oncotarget. 2014;5:9577-93 pubmed
	Yentrapalli R, Azimzadeh O, Sriharshan A, Malinowsky K, Merl J, Wojcik A, et al. The PI3K/Akt/mTOR pathway is implicated in the premature senescence of primary human endothelial cells exposed to chronic radiation. PLoS ONE. 2013;8:e70024 pubmed publisher
	Haslinger P, Haider S, Sonderegger S, Otten J, Pollheimer J, Whitley G, et al. AKT isoforms 1 and 3 regulate basal and epidermal growth factor-stimulated SGHPL-5 trophoblast cell migration in humans. Biol Reprod. 2013;88:54 pubmed publisher
	Agarwal N, Chen C, Cho H, Boulbès D, Spooner E, Sarbassov D. Rictor regulates cell migration by suppressing RhoGDI2. Oncogene. 2013;32:2521-6 pubmed publisher

product information

SKU :

4517S

Product-Name :

mTOR (L27D4) Mouse mAb

Size :

100 ul

Price-(USD) :

235 USD

Species-x-Reactivity :

H, M, R, Mk

Applications :

Western blot

Product-Category :

PI3K / Akt Signaling

Shipping-Temp :

AMBIENT

Storage-Temp :

-20°C

Product-Type :

Monoclonal Antibody

MW :

289

Host :

Mouse

Target :

mTOR

Primary-Protein :

mTOR

Alt-Names :

FK506 binding protein 12-rapamycin associated protein 1,FK506 binding protein 12-rapamycin associated protein 2,FK506-binding protein 12-rapamycin complex-associated protein 1,FKBP-rapamycin associated protein,FKBP12-rapamycin complex-associated protein,FKBP12-rapamycin complex-associated protein 1,FLJ44809,FRAP,FRAP1,FRAP2,Mammalian target of rapamycin,RAFT1,RAPT1,Rapamycin target protein 1,Serine/threonine-protein kinase mTOR,mTOR,mechanistic target of rapamycin (serine/threonine kinase),rapamycin and FKBP12 target 1,rapamycin associated protein FRAP2

more info or order :

Cell Signaling Technology product webpage