product summary
company name :
Cell Signaling Technology
product type :
antibody
product name :
Phospho-SEK1/MKK4 (Ser257) (C36C11) Rabbit mAb
catalog :
4514
clonality :
monoclonal
host :
domestic rabbit
conjugate :
nonconjugated
antigen modification :
phosphorylated
clone name :
C36C11
reactivity :
human, mouse, rat
application :
western blot, flow cytometry
more info or order :
Cell Signaling Technology product webpage
citations: 8
Published Application/Species/Sample/DilutionReference
  • western blot; mouse; loading ...; fig 6c
Ye P, Liu J, Xu W, Liu D, Ding X, Le S, et al. Dual-Specificity Phosphatase 26 Protects Against Nonalcoholic Fatty Liver Disease in Mice Through Transforming Growth Factor Beta-Activated Kinase 1 Suppression. Hepatology. 2019;69:1946-1964 pubmed publisher
  • western blot; human; fig 4f
Xiao N, Li H, Yu W, Gu C, Fang H, Peng Y, et al. SUMO-specific protease 2 (SENP2) suppresses keratinocyte migration by targeting NDR1 for de-SUMOylation. FASEB J. 2019;33:163-174 pubmed publisher
  • western blot; mouse; loading ...; fig s5e
Genovese G, Carugo A, TEPPER J, Robinson F, Li L, Svelto M, et al. Synthetic vulnerabilities of mesenchymal subpopulations in pancreatic cancer. Nature. 2017;542:362-366 pubmed publisher
  • western blot; human; 1:1000; loading ...; fig 6b
Farsam V, Basu A, Gatzka M, Treiber N, Schneider L, Mulaw M, et al. Senescent fibroblast-derived Chemerin promotes squamous cell carcinoma migration. Oncotarget. 2016;7:83554-83569 pubmed publisher
  • western blot; human; loading ...; fig 3e
Dunnill C, Ibraheem K, Mohamed A, Southgate J, Georgopoulos N. A redox state-dictated signalling pathway deciphers the malignant cell specificity of CD40-mediated apoptosis. Oncogene. 2017;36:2515-2528 pubmed publisher
  • western blot; mouse
Resch U, Cuapio A, Sturtzel C, Hofer E, de Martin R, Holper Schichl Y. Polyubiquitinated tristetraprolin protects from TNF-induced, caspase-mediated apoptosis. J Biol Chem. 2014;289:25088-100 pubmed publisher
Kashyap A, Fernandez Rodriguez L, Zhao Y, Monaco G, Trefny M, Yoshida N, et al. GEF-H1 Signaling upon Microtubule Destabilization Is Required for Dendritic Cell Activation and Specific Anti-tumor Responses. Cell Rep. 2019;28:3367-3380.e8 pubmed publisher
Lun X, Szklarczyk D, Gábor A, Dobberstein N, Zanotelli V, Saez Rodriguez J, et al. Analysis of the Human Kinome and Phosphatome by Mass Cytometry Reveals Overexpression-Induced Effects on Cancer-Related Signaling. Mol Cell. 2019;74:1086-1102.e5 pubmed publisher
product information
SKU :
4514P
Product-Name :
Phospho-SEK1/MKK4 (Ser257) (C36C11) Rabbit mAb
Size :
40 ul
Price-(USD) :
123 USD
Species-x-Reactivity :
H, M, R, Mk
Applications :
Flow cytometry
Product-Category :
MAP Kinase Signaling
Shipping-Temp :
AMBIENT
Storage-Temp :
-20°C
Product-Type :
Monoclonal Antibody
MW :
44
Host :
Rabbit
Target :
MKK4 (Ser257) phosphate
Primary-Protein :
MKK4
Alt-Names :
Dual specificity mitogen-activated protein kinase kinase 4,JNK activating kinase 1,JNK-activated kinase 1,JNK-activating kinase 1,JNKK,JNKK1,MAP kinase kinase 4,MAP2K4,MAPK/ERK kinase 4,MAPKK 4,MAPKK4,MEK 4,MEK4,MKK4,MP2K4,PRKMK4,SAPK/ERK kinase 1,SEK1,SERK1,c-Jun N-terminal kinase kinase 1,mitogen-activated protein kinase kinase 4
more info or order :
Cell Signaling Technology product webpage
company information
Cell Signaling Technology
3 Trask Lane
Danvers, MA 01923
info@cellsignal.com
https://www.cellsignal.com
8776162355
headquarters: USA
Established in Beverly, MA in 1999, Cell Signaling Technology (CST) is a privately-owned company with over 400 employees worldwide. We are dedicated to providing innovative research tools that are used to help define mechanisms underlying cell function and disease. Since its inception, CST has become the world leader in the production of the highest quality activation-state and total protein antibodies utilized to expand knowledge of cell signaling pathways. Our mission is to deliver the world's highest quality research tools that accelerate progress in biological research and personalized medicine.