product summary
company name :
Cell Signaling Technology
product type :
antibody
product name :
IRAK1 (D51G7) XP® Rabbit mAb
catalog :
4504S
quantity :
100 ul
price :
260 USD
clonality :
monoclonal
host :
rabbit
reactivity :
human, mouse
application :
western blot, immunocytochemistry, immunoprecipitation
more info or order :
Cell Signaling Technology product webpage
citations: 9
Published Application/Species/DilutionReference
  • western blot (knockout validation); human; fig 7
  • western blot; mouse; fig 8
Sun J, Li N, Oh K, Dutta B, Vayttaden S, Lin B, et al. Comprehensive RNAi-based screening of human and mouse TLR pathways identifies species-specific preferences in signaling protein use. Sci Signal. 2016;9:ra3 pubmed publisher
  • western blot; human
Emmerich C, Bakshi S, Kelsall I, Ortiz-Guerrero J, Shpiro N, Cohen P. Lys63/Met1-hybrid ubiquitin chains are commonly formed during the activation of innate immune signalling. Biochem Biophys Res Commun. 2016;474:452-61 pubmed publisher
  • western blot; human
Willy J, Young S, Stevens J, Masuoka H, Wek R. CHOP links endoplasmic reticulum stress to NF-κB activation in the pathogenesis of nonalcoholic steatohepatitis. Mol Biol Cell. 2015;26:2190-204 pubmed publisher
  • western blot; mouse; 1:500; fig 3
Alexander M, Hu R, Runtsch M, Kagele D, Mosbruger T, Tolmachova T, et al. Exosome-delivered microRNAs modulate the inflammatory response to endotoxin. Nat Commun. 2015;6:7321 pubmed publisher
  • western blot; human; 1:10000
Xiang M, Birkbak N, Vafaizadeh V, Walker S, Yeh J, Liu S, et al. STAT3 induction of miR-146b forms a feedback loop to inhibit the NF-κB to IL-6 signaling axis and STAT3-driven cancer phenotypes. Sci Signal. 2014;7:ra11 pubmed publisher
  • western blot; mouse; fig 6c
Xu L, Jin L, Zhang B, Akerlund L, Shu H, Cambier J. VISA is required for B cell expression of TLR7. J Immunol. 2012;188:248-58 pubmed publisher
Pallotta M, Orabona C, Volpi C, Vacca C, Belladonna M, Bianchi R, et al. Indoleamine 2,3-dioxygenase is a signaling protein in long-term tolerance by dendritic cells. Nat Immunol. 2011;12:870-8 pubmed publisher
Geraghty P, Dabo A, D'Armiento J. TLR4 protein contributes to cigarette smoke-induced matrix metalloproteinase-1 (MMP-1) expression in chronic obstructive pulmonary disease. J Biol Chem. 2011;286:30211-8 pubmed publisher
Hulsmans M, Van Dooren E, Mathieu C, Holvoet P. Decrease of miR-146b-5p in monocytes during obesity is associated with loss of the anti-inflammatory but not insulin signaling action of adiponectin. PLoS ONE. 2012;7:e32794 pubmed publisher
product information
SKU :
4504S
Product-Name :
IRAK1 (D51G7) XP® Rabbit mAb
Size :
100 ul
Price-(USD) :
260 USD
Species-x-Reactivity :
H, M, Mk
Applications :
Immunofluorescence (Immunocytochemistry)
Product-Category :
Immunology and Inflammation
Shipping-Temp :
AMBIENT
Storage-Temp :
-20°C
Product-Type :
Monoclonal Antibody
MW :
78, 105
Host :
Rabbit
Target :
IRAK1
Primary-Protein :
IRAK1
Alt-Names :
IRAK,IRAK-1,IRAK1,Interleukin-1 receptor-associated kinase 1,Pelle homolog,pelle
more info or order :
Cell Signaling Technology product webpage
company information
Cell Signaling Technology
3 Trask Lane
Danvers, MA 01923
info@cellsignal.com
www.cellsignal.com
8776162355
headquarters: USA
Established in Beverly, MA in 1999, Cell Signaling Technology (CST) is a privately-owned company with over 400 employees worldwide. We are dedicated to providing innovative research tools that are used to help define mechanisms underlying cell function and disease. Since its inception, CST has become the world leader in the production of the highest quality activation-state and total protein antibodies utilized to expand knowledge of cell signaling pathways. Our mission is to deliver the world's highest quality research tools that accelerate progress in biological research and personalized medicine.