product summary
company name :
Cell Signaling Technology
product type :
antibody
product name :
A-Raf Antibody
catalog :
4432
clonality :
polyclonal
host :
rabbit
conjugate :
nonconjugated
reactivity :
human, mouse, rat
application :
western blot, immunoprecipitation, other
citations: 4
Published Application/Species/Sample/DilutionReference
  • other; human; loading ...; fig 4c
Ng P, Li J, Jeong K, Shao S, Chen H, Tsang Y, et al. Systematic Functional Annotation of Somatic Mutations in Cancer. Cancer Cell. 2018;33:450-462.e10 pubmed publisher
  • western blot; human; loading ...; fig 4a
Vakana E, Pratt S, Blosser W, Dowless M, Simpson N, Yuan X, et al. LY3009120, a panRAF inhibitor, has significant anti-tumor activity in BRAF and KRAS mutant preclinical models of colorectal cancer. Oncotarget. 2017;8:9251-9266 pubmed publisher
Nieto P, Ambrogio C, Esteban Burgos L, Gómez López G, Blasco M, Yao Z, et al. A Braf kinase-inactive mutant induces lung adenocarcinoma. Nature. 2017;548:239-243 pubmed publisher
Tap W, Gong K, Dering J, Tseng Y, Ginther C, Pauletti G, et al. Pharmacodynamic characterization of the efficacy signals due to selective BRAF inhibition with PLX4032 in malignant melanoma. Neoplasia. 2010;12:637-49 pubmed
product information
SKU :
4432P
Product-Name :
A-Raf Antibody
Size :
40 ul
Price-(USD) :
123 USD
Species-x-Reactivity :
H, M, R
Applications :
Immunoprecipitation
Product-Category :
MAP Kinase Signaling
Shipping-Temp :
AMBIENT
Storage-Temp :
-20°C
Product-Type :
Polyclonal Antibody
MW :
68
Host :
Rabbit
Target :
A-Raf
Primary-Protein :
A-Raf
Alt-Names :
A-RAF,A-Raf proto-oncogene serine/threonine-protein kinase,ARAF,ARAF1,Oncogene ARAF1,PKS,PKS2,Proto-oncogene A-Raf,Proto-oncogene A-Raf-1,Proto-oncogene Pks,RAFA1,Ras-binding protein DA-Raf,Serine/threonine-protein kinase A-Raf,v-raf murine sarcoma 3611 viral oncogene homolog,v-raf murine sarcoma 3611 viral oncogene homolog 1
company information
Cell Signaling Technology
3 Trask Lane
Danvers, MA 01923
info@cellsignal.com
www.cellsignal.com
8776162355
headquarters: USA
Established in Beverly, MA in 1999, Cell Signaling Technology (CST) is a privately-owned company with over 400 employees worldwide. We are dedicated to providing innovative research tools that are used to help define mechanisms underlying cell function and disease. Since its inception, CST has become the world leader in the production of the highest quality activation-state and total protein antibodies utilized to expand knowledge of cell signaling pathways. Our mission is to deliver the world's highest quality research tools that accelerate progress in biological research and personalized medicine.