product summary
company name :
Cell Signaling Technology
product type :
antibody
product name :
FTH1 (D1D4) Rabbit mAb
catalog :
4393
clonality :
monoclonal
host :
domestic rabbit
conjugate :
nonconjugated
clone name :
D1D4
reactivity :
human, mouse, rat
application :
western blot, immunocytochemistry, immunoprecipitation, immunohistochemistry - paraffin section
citations: 8
Published Application/Species/Sample/DilutionReference
  • western blot; human; 1:25,000; fig 2e
Fisher A, Sangkhae V, Balusikova K, Palaskas N, Ganz T, Nemeth E. Iron-dependent apoptosis causes embryotoxicity in inflamed and obese pregnancy. Nat Commun. 2021;12:4026 pubmed publisher
  • western blot; rat; loading ...; fig 4a, 4c
Chang B, Guan H, Wang X, Chen Z, Zhu W, Wei X, et al. Cox4i2 Triggers an Increase in Reactive Oxygen Species, Leading to Ferroptosis and Apoptosis in HHV7 Infected Schwann Cells. Front Mol Biosci. 2021;8:660072 pubmed publisher
  • western blot; human; 1:1000; fig s5c
Goldfarb A, Freeman K, Sahu R, Elagib K, Holy M, Arneja A, et al. Iron control of erythroid microtubule cytoskeleton as a potential target in treatment of iron-restricted anemia. Nat Commun. 2021;12:1645 pubmed publisher
  • immunohistochemistry - paraffin section; mouse; 1:500; loading ...; fig 2c
  • western blot; mouse; loading ...; fig 1b
Santana Codina N, Gableske S, Quiles Del Rey M, Małachowska B, Jedrychowski M, Biancur D, et al. NCOA4 maintains murine erythropoiesis via cell autonomous and non-autonomous mechanisms. Haematologica. 2019;: pubmed publisher
  • western blot; human; 1:1000; loading ...; fig 1g
Goodwin J, Dowdle W, Dejesus R, Wang Z, Bergman P, Kobylarz M, et al. Autophagy-Independent Lysosomal Targeting Regulated by ULK1/2-FIP200 and ATG9. Cell Rep. 2017;20:2341-2356 pubmed publisher
  • western blot; human; 1:500; loading ...; fig 3c
Mrowczynski O, Madhankumar A, Slagle Webb B, Lee S, Zacharia B, Connor J. HFE genotype affects exosome phenotype in cancer. Biochim Biophys Acta Gen Subj. 2017;1861:1921-1928 pubmed publisher
  • immunocytochemistry; human; 1:100; fig 5
  • western blot; human; 1:1000; fig 7
Dowdle W, Nyfeler B, Nagel J, Elling R, Liu S, Triantafellow E, et al. Selective VPS34 inhibitor blocks autophagy and uncovers a role for NCOA4 in ferritin degradation and iron homeostasis in vivo. Nat Cell Biol. 2014;16:1069-79 pubmed publisher
Mancias J, Pontano Vaites L, Nissim S, Biancur D, Kim A, Wang X, et al. Ferritinophagy via NCOA4 is required for erythropoiesis and is regulated by iron dependent HERC2-mediated proteolysis. elife. 2015;4: pubmed publisher
product information
SKU :
4393S
Product-Name :
FTH1 (D1D4) Rabbit mAb
Size :
100 ul
Price-(USD) :
235 USD
Species-x-Reactivity :
H, M, R, Mk
Applications :
Immunoprecipitation
Product-Category :
Metabolism
Shipping-Temp :
AMBIENT
Storage-Temp :
-20°C
Product-Type :
Monoclonal Antibody
MW :
21
Host :
Rabbit
Target :
Ferritin H
Primary-Protein :
ferritin H
Alt-Names :
Cell proliferation-inducing gene 15 protein,FHC,FRIH,FTH,FTH1,FTHL6,Ferritin H subunit,Ferritin heavy chain,MGC104426,PIG15,PLIF,apoferritin,ferritin, heavy polypeptide 1,placenta immunoregulatory factor,proliferation-inducing protein 15
company information
Cell Signaling Technology
3 Trask Lane
Danvers, MA 01923
info@cellsignal.com
https://www.cellsignal.com
8776162355
headquarters: USA
Established in Beverly, MA in 1999, Cell Signaling Technology (CST) is a privately-owned company with over 400 employees worldwide. We are dedicated to providing innovative research tools that are used to help define mechanisms underlying cell function and disease. Since its inception, CST has become the world leader in the production of the highest quality activation-state and total protein antibodies utilized to expand knowledge of cell signaling pathways. Our mission is to deliver the world's highest quality research tools that accelerate progress in biological research and personalized medicine.