| Published Application/Species/Dilution | Reference |
|---|
- western blot (knockdown validation); human; fig s1
| Hensel J, Duex J, Owens C, Dancik G, Edwards M, Frierson H, et al. Patient Mutation Directed shRNA Screen Uncovers Novel Bladder Tumor Growth Suppressors. Mol Cancer Res. 2015;13:1306-15 pubmed publisher |
- western blot; mouse; 1:2000; fig S11
| Gautheron J, Vucur M, Schneider A, Severi I, Roderburg C, Roy S, et al. The necroptosis-inducing kinase RIPK3 dampens adipose tissue inflammation and glucose intolerance. Nat Commun. 2016;7:11869 pubmed publisher |
- western blot; human; fig 1
| Yoshida T, Song L, Bai Y, Kinose F, Li J, Ohaegbulam K, et al. ZEB1 Mediates Acquired Resistance to the Epidermal Growth Factor Receptor-Tyrosine Kinase Inhibitors in Non-Small Cell Lung Cancer. PLoS ONE. 2016;11:e0147344 pubmed publisher |
- western blot; human; fig 1
| Debruyne D, Bhatnagar N, Sharma B, Luther W, Moore N, Cheung N, et al. ALK inhibitor resistance in ALK(F1174L)-driven neuroblastoma is associated with AXL activation and induction of EMT. Oncogene. 2016;35:3681-91 pubmed publisher |
- western blot; mouse; fig s5
| Krause C, Popp O, Thirunarayanan N, Dittmar G, Lipp M, Müller G. MicroRNA-34a promotes genomic instability by a broad suppression of genome maintenance mechanisms downstream of the oncogene KSHV-vGPCR. Oncotarget. 2016;7:10414-32 pubmed publisher |
- western blot; human; fig 6
| Hudson C, McArdle C, López Bernal A. Steroid receptor co-activator interacting protein (SIP) mediates EGF-stimulated expression of the prostaglandin synthase COX2 and prostaglandin release in human myometrium. Mol Hum Reprod. 2016;: pubmed |
- western blot; human; fig 3
| Kline C, van den Heuvel A, Allen J, Prabhu V, Dicker D, El-Deiry W. ONC201 kills solid tumor cells by triggering an integrated stress response dependent on ATF4 activation by specific eIF2α kinases. Sci Signal. 2016;9:ra18 pubmed publisher |
- western blot; human; fig 3d
| Chan A, Punwani D, Kadlecek T, Cowan M, Olson J, Mathes E, et al. A novel human autoimmune syndrome caused by combined hypomorphic and activating mutations in ZAP-70. J Exp Med. 2016;213:155-65 pubmed publisher |
- western blot; mouse; fig 2
| Yu H. Sphingosine-1-Phosphate Receptor 2 Regulates Proinflammatory Cytokine Production and Osteoclastogenesis. PLoS ONE. 2016;11:e0156303 pubmed publisher |
- other; human; 1:50; fig 5e
- western blot; human; 1:1000; fig 5a
| Padhan N, Nordling T, Sundstrom M, Akerud P, Birgisson H, Nygren P, et al. High sensitivity isoelectric focusing to establish a signaling biomarker for the diagnosis of human colorectal cancer. BMC Cancer. 2016;16:683 pubmed publisher |
| Greenfeld H, Takasaki K, Walsh M, Ersing I, Bernhardt K, Ma Y, et al. TRAF1 Coordinates Polyubiquitin Signaling to Enhance Epstein-Barr Virus LMP1-Mediated Growth and Survival Pathway Activation. PLoS Pathog. 2015;11:e1004890 pubmed publisher |
- western blot; human; 1:2000; fig 5
| Carnesecchi J, Malbouyres M, de Mets R, Balland M, Beauchef G, Vie K, et al. Estrogens induce rapid cytoskeleton re-organization in human dermal fibroblasts via the non-classical receptor GPR30. PLoS ONE. 2015;10:e0120672 pubmed publisher |
- western blot; mouse; fig 1
| Lee E, Park E, Mun H, Chang E, Ko J, Kim D, et al. Soluble receptor for advanced glycation end products inhibits disease progression in autosomal dominant polycystic kidney disease by down-regulating cell proliferation. FASEB J. 2015;29:3506-14 pubmed publisher |
- western blot; mouse; fig 8
| Salotti J, Sakchaisri K, Tourtellotte W, Johnson P. An Arf-Egr-C/EBPβ pathway linked to ras-induced senescence and cancer. Mol Cell Biol. 2015;35:866-83 pubmed publisher |
| Rios-Doria J, Sabol D, Chesebrough J, Stewart D, Xu L, Tammali R, et al. A Monoclonal Antibody to ADAM17 Inhibits Tumor Growth by Inhibiting EGFR and Non-EGFR-Mediated Pathways. Mol Cancer Ther. 2015;14:1637-49 pubmed publisher |
- western blot; human; 1:1000; fig s3c
| SCANLON C, Banerjee R, Inglehart R, Liu M, Russo N, Hariharan A, et al. Galanin modulates the neural niche to favour perineural invasion in head and neck cancer. Nat Commun. 2015;6:6885 pubmed publisher |
- western blot; sheep; 1:2500
| Boeldt D, Grummer M, YI F, Magness R, Bird I. Phosphorylation of Ser-279/282 and Tyr-265 positions on Cx43 as possible mediators of VEGF-165 inhibition of pregnancy-adapted Ca2+ burst function in ovine uterine artery endothelial cells. Mol Cell Endocrinol. 2015;412:73-84 pubmed publisher |
- flow cytometry; human; fig 2
- western blot; human; fig 2
| Ksionda O, Melton A, Bache J, Tenhagen M, Bakker J, Harvey R, et al. RasGRP1 overexpression in T-ALL increases basal nucleotide exchange on Ras rendering the Ras/PI3K/Akt pathway responsive to protumorigenic cytokines. Oncogene. 2015;: pubmed publisher |
- western blot; human; 1:1500; fig st8
| Hayashi Y, Bardsley M, Toyomasu Y, Milosavljevic S, Gajdos G, Choi K, et al. Platelet-Derived Growth Factor Receptor-α Regulates Proliferation of Gastrointestinal Stromal Tumor Cells With Mutations in KIT by Stabilizing ETV1. Gastroenterology. 2015;149:420-32.e16 pubmed publisher |
- western blot; mouse; 1:500; fig 4
| Boncompagni S, Arthurton L, Akujuru E, Pearson T, Steverding D, Protasi F, et al. Membrane glucocorticoid receptors are localised in the extracellular matrix and signal through the MAPK pathway in mammalian skeletal muscle fibres. J Physiol. 2015;593:2679-92 pubmed publisher |
- western blot; human; fig 7
| Garcia-Cano J, Ambroise G, Pascual-Serra R, Carrión M, Serrano-Oviedo L, Ortega-Muelas M, et al. Exploiting the potential of autophagy in cisplatin therapy: A new strategy to overcome resistance. Oncotarget. 2015;6:15551-65 pubmed |
- western blot; human; 1:1000
| Narumi K, Hirose T, Sato E, Mori T, Kisu K, Ishikawa M, et al. A functional (pro)renin receptor is expressed in human lymphocytes and monocytes. Am J Physiol Renal Physiol. 2015;308:F487-99 pubmed publisher |
- western blot; mouse; 1:1000; fig s6
| Sathyamurthy A, Yin D, Barik A, Shen C, Bean J, Figueiredo D, et al. ERBB3-mediated regulation of Bergmann glia proliferation in cerebellar lamination. Development. 2015;142:522-32 pubmed publisher |
- western blot; mouse; fig 6
| Ketema M, Secades P, Kreft M, Nahidiazar L, Janssen H, Jalink K, et al. The rod domain is not essential for the function of plectin in maintaining tissue integrity. Mol Biol Cell. 2015;26:2402-17 pubmed publisher |
- western blot; human; fig 2
| Momeny M, Saunus J, Marturana F, McCart Reed A, Black D, Sala G, et al. Heregulin-HER3-HER2 signaling promotes matrix metalloproteinase-dependent blood-brain-barrier transendothelial migration of human breast cancer cell lines. Oncotarget. 2015;6:3932-46 pubmed |
- western blot; rat; 1:1000; fig 3
| Hruska M, Henderson N, Xia N, Le Marchand S, Dalva M. Anchoring and synaptic stability of PSD-95 is driven by ephrin-B3. Nat Neurosci. 2015;18:1594-605 pubmed publisher |
| Muro R, Nitta T, Okada T, Ideta H, Tsubata T, Suzuki H. The Ras GTPase-activating protein Rasal3 supports survival of naive T cells. PLoS ONE. 2015;10:e0119898 pubmed publisher |
| Münzberg C, Höhn K, Krndija D, Maas U, Bartsch D, Slater E, et al. IGF-1 drives chromogranin A secretion via activation of Arf1 in human neuroendocrine tumour cells. J Cell Mol Med. 2015;19:948-59 pubmed publisher |
| Lee M, Smith S, Murray S, Pham L, Minoo P, Nielsen H. Dihydrotestosterone potentiates EGF-induced ERK activation by inducing SRC in fetal lung fibroblasts. Am J Respir Cell Mol Biol. 2014;51:114-24 pubmed publisher |
| Hu J, Cheng Y, Li Y, Jin Z, Pan Y, Liu G, et al. microRNA-128 plays a critical role in human non-small cell lung cancer tumourigenesis, angiogenesis and lymphangiogenesis by directly targeting vascular endothelial growth factor-C. Eur J Cancer. 2014;50:2336-50 pubmed publisher |
| Lamprecht M, Morrison B. GPR30 activation is neither necessary nor sufficient for acute neuroprotection by 17β-estradiol after an ischemic injury in organotypic hippocampal slice cultures. Brain Res. 2014;1563:131-7 pubmed publisher |
| Ost M, Werner F, Dokas J, Klaus S, Voigt A. Activation of AMPKα2 is not crucial for mitochondrial uncoupling-induced metabolic effects but required to maintain skeletal muscle integrity. PLoS ONE. 2014;9:e94689 pubmed publisher |
- western blot; mouse; fig s1
| Au-Yeung B, Melichar H, Ross J, Cheng D, Zikherman J, Shokat K, et al. Quantitative and temporal requirements revealed for Zap70 catalytic activity during T cell development. Nat Immunol. 2014;15:687-94 pubmed publisher |
- immunohistochemistry - paraffin section; mouse
- western blot; mouse
| Park E, Kim B, Lee E, Chang E, Kim D, Choi S, et al. Targeting of receptor for advanced glycation end products suppresses cyst growth in polycystic kidney disease. J Biol Chem. 2014;289:9254-62 pubmed publisher |
| Cazanave S, Wang X, Zhou H, Rahmani M, Grant S, Durrant D, et al. Degradation of Keap1 activates BH3-only proteins Bim and PUMA during hepatocyte lipoapoptosis. Cell Death Differ. 2014;21:1303-12 pubmed publisher |
- western blot; mouse; 1:500
| Ribeiro M, Rosenstock T, Oliveira A, Oliveira C, Rego A. Insulin and IGF-1 improve mitochondrial function in a PI-3K/Akt-dependent manner and reduce mitochondrial generation of reactive oxygen species in Huntington's disease knock-in striatal cells. Free Radic Biol Med. 2014;74:129-44 pubmed publisher |
| Tang J, Shen L, Yang Q, Zhang C. Overexpression of metadherin mediates metastasis of osteosarcoma by regulating epithelial-mesenchymal transition. Cell Prolif. 2014;47:427-34 pubmed publisher |
| Blaabjerg L, Christensen G, Matsumoto M, van der Meulen T, Huising M, Billestrup N, et al. CRFR1 activation protects against cytokine-induced β-cell death. J Mol Endocrinol. 2014;53:417-27 pubmed publisher |
| Singel S, Batten K, Cornelius C, Jia G, Fasciani G, Barron S, et al. Receptor-interacting protein kinase 2 promotes triple-negative breast cancer cell migration and invasion via activation of nuclear factor-kappaB and c-Jun N-terminal kinase pathways. Breast Cancer Res. 2014;16:R28 pubmed publisher |
- western blot; mouse; 1:2500
| Anchan D, Clark S, Pollard K, Vasudevan N. GPR30 activation decreases anxiety in the open field test but not in the elevated plus maze test in female mice. Brain Behav. 2014;4:51-9 pubmed publisher |
- western blot; human; 1:1000
| Henderson Y, Toro-Serra R, Chen Y, Ryu J, Frederick M, Zhou G, et al. Src inhibitors in suppression of papillary thyroid carcinoma growth. Head Neck. 2014;36:375-84 pubmed publisher |
| Okada T, Nitta T, Kaji K, Takashima A, Oda H, Tamehiro N, et al. Differential function of Themis CABIT domains during T cell development. PLoS ONE. 2014;9:e89115 pubmed publisher |
- western blot; human; 1:1000
- western blot; mouse; 1:1000
| Dou W, Zhang J, Ren G, Ding L, Sun A, Deng C, et al. Mangiferin attenuates the symptoms of dextran sulfate sodium-induced colitis in mice via NF-κB and MAPK signaling inactivation. Int Immunopharmacol. 2014;23:170-8 pubmed publisher |
- western blot; human; fig 6
| Candelaria N, Addanki S, Zheng J, Nguyen-Vu T, Karaboga H, Dey P, et al. Antiproliferative effects and mechanisms of liver X receptor ligands in pancreatic ductal adenocarcinoma cells. PLoS ONE. 2014;9:e106289 pubmed publisher |
| Feng C, Zhang Y, Yin J, Li J, Abounader R, Zuo Z. Regulatory factor X1 is a new tumor suppressive transcription factor that acts via direct downregulation of CD44 in glioblastoma. Neuro Oncol. 2014;16:1078-85 pubmed publisher |
| Gürtler C, Carty M, Kearney J, Schattgen S, Ding A, Fitzgerald K, et al. SARM regulates CCL5 production in macrophages by promoting the recruitment of transcription factors and RNA polymerase II to the Ccl5 promoter. J Immunol. 2014;192:4821-32 pubmed publisher |
| Zhang S, Ren M, Zeng X, He P, Ma X, Qiao S. Leucine stimulates ASCT2 amino acid transporter expression in porcine jejunal epithelial cell line (IPEC-J2) through PI3K/Akt/mTOR and ERK signaling pathways. Amino Acids. 2014;46:2633-42 pubmed publisher |
| Lu J, Chang Y, Wang C, Lin Y, Lin C, Wu Z. Trichostatin A modulates thiazolidinedione-mediated suppression of tumor necrosis factor α-induced lipolysis in 3T3-L1 adipocytes. PLoS ONE. 2013;8:e71517 pubmed publisher |
- immunohistochemistry; mouse
- western blot; mouse
| Cieslik K, Trial J, Carlson S, Taffet G, Entman M. Aberrant differentiation of fibroblast progenitors contributes to fibrosis in the aged murine heart: role of elevated circulating insulin levels. FASEB J. 2013;27:1761-71 pubmed publisher |
- western blot; mouse; 1:1000
| Udagawa T, Farny N, Jakovcevski M, Kaphzan H, Alarcon J, Anilkumar S, et al. Genetic and acute CPEB1 depletion ameliorate fragile X pathophysiology. Nat Med. 2013;19:1473-7 pubmed publisher |
- immunohistochemistry - paraffin section; human; 1:100
- western blot; human
| Kucherlapati M, Esfahani S, Habibollahi P, Wang J, Still E, Bronson R, et al. Genotype directed therapy in murine mismatch repair deficient tumors. PLoS ONE. 2013;8:e68817 pubmed publisher |
| Beckham T, Cheng J, Lu P, Shao Y, Troyer D, Lance R, et al. Acid ceramidase induces sphingosine kinase 1/S1P receptor 2-mediated activation of oncogenic Akt signaling. Oncogenesis. 2013;2:e49 pubmed publisher |
| Lin S, Hoffmann K, Xiao Z, Jin N, Galli U, Mohr E, et al. MEK inhibition induced downregulation of MRP1 and MRP3 expression in experimental hepatocellular carcinoma. Cancer Cell Int. 2013;13:3 pubmed publisher |
| Li W, Wei S, Liu C, Song M, Wu H, Yang Y. Regulation of the osteogenic and adipogenic differentiation of bone marrow-derived stromal cells by extracellular uridine triphosphate: The role of P2Y2 receptor and ERK1/2 signaling. Int J Mol Med. 2016;37:63-73 pubmed publisher |
| Obino D, Farina F, Malbec O, Sáez P, Maurin M, Gaillard J, et al. Actin nucleation at the centrosome controls lymphocyte polarity. Nat Commun. 2016;7:10969 pubmed publisher |
| Olayanju A, Copple I, Bryan H, Edge G, Sison R, Wong M, et al. Brusatol provokes a rapid and transient inhibition of Nrf2 signaling and sensitizes mammalian cells to chemical toxicity-implications for therapeutic targeting of Nrf2. Free Radic Biol Med. 2015;78:202-12 pubmed publisher |
| Meng M, Wang H, Guo W, Wu Z, Zeng X, Zaorsky N, et al. Targeting pyruvate kinase M2 contributes to radiosensitivity of non-small cell lung cancer cells in vitro and in vivo. Cancer Lett. 2015;356:985-93 pubmed publisher |
| Chen J, Li L, Su J, Li B, Chen T, Wong Y. Synergistic apoptosis-inducing effects on A375 human melanoma cells of natural borneol and curcumin. PLoS ONE. 2014;9:e101277 pubmed publisher |
| Mori M, Ueno Y, Konagai S, Fushiki H, Shimada I, Kondoh Y, et al. The selective anaplastic lymphoma receptor tyrosine kinase inhibitor ASP3026 induces tumor regression and prolongs survival in non-small cell lung cancer model mice. Mol Cancer Ther. 2014;13:329-40 pubmed publisher |
| Byun K, Bayarsaikhan D, Bayarsaikhan E, Son M, Oh S, Lee J, et al. Microglial AGE-albumin is critical in promoting alcohol-induced neurodegeneration in rats and humans. PLoS ONE. 2014;9:e104699 pubmed publisher |
| Zhu Q, Hu J, Meng H, Shen Y, Zhou J, Zhu Z. S-phase cell cycle arrest, apoptosis, and molecular mechanisms of aplasia ras homolog member I-induced human ovarian cancer SKOV3 cell lines. Int J Gynecol Cancer. 2014;24:629-34 pubmed publisher |
| Sun L, Zhao R, Lan X, Chen R, Wang S, Du G. Goniolactone C, a styryl lactone derivative, inhibits PDGF-BB-induced vascular smooth muscle cell migration and proliferation via PDGFR/ERK signaling. Molecules. 2014;19:19501-15 pubmed publisher |
| Wu A, Dalvi P, Lu X, Yang M, Riddick D, Matthews J, et al. Induction of multidrug resistance transporter ABCG2 by prolactin in human breast cancer cells. Mol Pharmacol. 2013;83:377-88 pubmed publisher |
| Zhang H, Yea K, Xie J, Ruiz D, Wilson I, Lerner R. Selecting agonists from single cells infected with combinatorial antibody libraries. Chem Biol. 2013;20:734-41 pubmed publisher |
| Cao Y, Xia D, Qi S, Du J, Ma P, Wang S, et al. Epiregulin can promote proliferation of stem cells from the dental apical papilla via MEK/Erk and JNK signalling pathways. Cell Prolif. 2013;46:447-56 pubmed publisher |
| Daley S, Coakley K, Hu D, Randall K, Jenne C, Limnander A, et al. Rasgrp1 mutation increases naive T-cell CD44 expression and drives mTOR-dependent accumulation of Helios⁺ T cells and autoantibodies. elife. 2013;2:e01020 pubmed publisher |
| Zimmerman E, Turner D, Buaboonnam J, Hu S, Orwick S, Roberts M, et al. Crenolanib is active against models of drug-resistant FLT3-ITD-positive acute myeloid leukemia. Blood. 2013;122:3607-15 pubmed publisher |
| Sydor S, Gu Y, Schlattjan M, Bechmann L, Rauen U, Best J, et al. Steatosis does not impair liver regeneration after partial hepatectomy. Lab Invest. 2013;93:20-30 pubmed publisher |
| Bjerre C, Vinther L, Belling K, Würtz S, Yadav R, Lademann U, et al. TIMP1 overexpression mediates resistance of MCF-7 human breast cancer cells to fulvestrant and down-regulates progesterone receptor expression. Tumour Biol. 2013;34:3839-51 pubmed publisher |
| Messal N, Mamessier E, Sylvain A, Celis-Gutierrez J, Thibult M, Chetaille B, et al. Differential role for CD277 as a co-regulator of the immune signal in T and NK cells. Eur J Immunol. 2011;41:3443-54 pubmed publisher |
| Zhang X, Ding L, Kang L, Wang Z. Estrogen receptor-alpha 36 mediates mitogenic antiestrogen signaling in ER-negative breast cancer cells. PLoS ONE. 2012;7:e30174 pubmed publisher |
| Zhang X, Ding L, Kang L, Wang Z. Involvement of ER-α36, Src, EGFR and STAT5 in the biphasic estrogen signaling of ER-negative breast cancer cells. Oncol Rep. 2012;27:2057-65 pubmed publisher |
| Zhang X, Meng J, Wang Z. A switch role of Src in the biphasic EGF signaling of ER-negative breast cancer cells. PLoS ONE. 2012;7:e41613 pubmed publisher |
| Werner S, Dotzlaf J, Smith R. MMP-28 as a regulator of myelination. BMC Neurosci. 2008;9:83 pubmed publisher |
| Reuter K, Loitsch S, Dignass A, Steinhilber D, Stein J. Selective non-steroidal glucocorticoid receptor agonists attenuate inflammation but do not impair intestinal epithelial cell restitution in vitro. PLoS ONE. 2012;7:e29756 pubmed publisher |
| Deane J, Kharas M, Oak J, Stiles L, Luo J, Moore T, et al. T-cell function is partially maintained in the absence of class IA phosphoinositide 3-kinase signaling. Blood. 2007;109:2894-902 pubmed |
| Mark J, Aubin R, Smith S, Hefford M. Inhibition of mitogen-activated protein kinase phosphatase 3 activity by interdomain binding. J Biol Chem. 2008;283:28574-83 pubmed publisher |
| Chen A, Kleiboeker S, Qiu J. Productive parvovirus B19 infection of primary human erythroid progenitor cells at hypoxia is regulated by STAT5A and MEK signaling but not HIFα. PLoS Pathog. 2011;7:e1002088 pubmed publisher |
| Paul J, Maiti K, Read M, Hure A, Smith J, Chan E, et al. Phasic phosphorylation of caldesmon and ERK 1/2 during contractions in human myometrium. PLoS ONE. 2011;6:e21542 pubmed publisher |
| Gross A, Lyandres J, Panigrahi A, Prak E, DeFranco A. Developmental acquisition of the Lyn-CD22-SHP-1 inhibitory pathway promotes B cell tolerance. J Immunol. 2009;182:5382-92 pubmed publisher |
| Lv X, Chen S, Li J, Fang J, Guo Y, Ding K. Lobolide, a diterpene, blockades the NF-κB pathway and p38 and ERK MAPK activity in macrophages in vitro. Acta Pharmacol Sin. 2012;33:1293-300 pubmed publisher |
| Moura E, Silva E, Serrão M, Afonso J, Kozmus C, Vieira-Coelho M. α2C-Adrenoceptors modulate L-DOPA uptake in opossum kidney cells and in the mouse kidney. Am J Physiol Renal Physiol. 2012;303:F928-38 pubmed publisher |
| Wu M, Desai D, Kakarla S, Katta A, Paturi S, Gutta A, et al. Acetaminophen prevents aging-associated hyperglycemia in aged rats: effect of aging-associated hyperactivation of p38-MAPK and ERK1/2. Diabetes Metab Res Rev. 2009;25:279-86 pubmed publisher |
| Trampont P, Zhang L, Ravichandran K. ShcA mediates the dominant pathway to extracellular signal-regulated kinase activation during early thymic development. Mol Cell Biol. 2006;26:9035-44 pubmed |
| Fehrenbacher N, Bastholm L, Kirkegaard-Sørensen T, Rafn B, Bøttzauw T, Nielsen C, et al. Sensitization to the lysosomal cell death pathway by oncogene-induced down-regulation of lysosome-associated membrane proteins 1 and 2. Cancer Res. 2008;68:6623-33 pubmed publisher |
| Chiron D, Pellat-Deceunynck C, Amiot M, Bataille R, Jego G. TLR3 ligand induces NF-{kappa}B activation and various fates of multiple myeloma cells depending on IFN-{alpha} production. J Immunol. 2009;182:4471-8 pubmed publisher |
| Owaki T, Asakawa M, Fukai F, Mizuguchi J, Yoshimoto T. IL-27 induces Th1 differentiation via p38 MAPK/T-bet- and intercellular adhesion molecule-1/LFA-1/ERK1/2-dependent pathways. J Immunol. 2006;177:7579-87 pubmed |
