product summary
company name :
Cell Signaling Technology
product type :
antibody
product name :
Phospho-Bad (Ser136) (D25H8) Rabbit mAb
catalog :
4366
clonality :
monoclonal
host :
rabbit
conjugate :
nonconjugated
antigen modification :
phosphorylated
clone name :
D25H8
reactivity :
human, mouse, rat
application :
western blot, immunoprecipitation
citations: 19
Published Application/Species/Sample/DilutionReference
  • western blot; mouse; 1:1000; loading ...; fig 2b
Ahmed S, Macara I. The Par3 polarity protein is an exocyst receptor essential for mammary cell survival. Nat Commun. 2017;8:14867 pubmed publisher
  • western blot; human; loading ...; fig 5a
Li Y, Buijs Gladdines J, Canté Barrett K, Stubbs A, Vroegindeweij E, Smits W, et al. IL-7 Receptor Mutations and Steroid Resistance in Pediatric T cell Acute Lymphoblastic Leukemia: A Genome Sequencing Study. PLoS Med. 2016;13:e1002200 pubmed publisher
  • western blot; human; fig 4e
Takagi Y, Shimada K, Shimada S, Sakamoto A, Naoe T, Nakamura S, et al. SPIB is a novel prognostic factor in diffuse large B-cell lymphoma that mediates apoptosis via the PI3K-AKT pathway. Cancer Sci. 2016;107:1270-80 pubmed publisher
  • western blot; mouse; fig 6
Tejada T, Tan L, Torres R, Calvert J, Lambert J, Zaidi M, et al. IGF-1 degradation by mouse mast cell protease 4 promotes cell death and adverse cardiac remodeling days after a myocardial infarction. Proc Natl Acad Sci U S A. 2016;113:6949-54 pubmed publisher
  • western blot; mouse; 1:1000; tbl 1
Guillot F, Kemppainen S, Lavasseur G, Miettinen P, Laroche S, Tanila H, et al. Brain-Specific Basal and Novelty-Induced Alternations in PI3K-Akt and MAPK/ERK Signaling in a Middle-Aged AβPP/PS1 Mouse Model of Alzheimer's Disease. J Alzheimers Dis. 2016;51:1157-73 pubmed publisher
  • western blot; human; fig 5
Urnukhsaikhan E, Cho H, Mishig Ochir T, Seo Y, Park J. Pulsed electromagnetic fields promote survival and neuronal differentiation of human BM-MSCs. Life Sci. 2016;151:130-138 pubmed publisher
  • western blot; human; fig 4
Luey B, May F. Insulin-like growth factors are essential to prevent anoikis in oestrogen-responsive breast cancer cells: importance of the type I IGF receptor and PI3-kinase/Akt pathway. Mol Cancer. 2016;15:8 pubmed publisher
  • western blot; rat; 1:1000; fig 4
Zhang H, Xiong Z, Wang J, Zhang S, Lei L, Yang L, et al. Glucagon-like peptide-1 protects cardiomyocytes from advanced oxidation protein product-induced apoptosis via the PI3K/Akt/Bad signaling pathway. Mol Med Rep. 2016;13:1593-601 pubmed publisher
  • western blot; human; fig 2
Moody S, Schinzel A, Singh S, Izzo F, Strickland M, Luo L, et al. PRKACA mediates resistance to HER2-targeted therapy in breast cancer cells and restores anti-apoptotic signaling. Oncogene. 2015;34:2061-71 pubmed publisher
  • western blot; mouse; 1:1000; fig 3
Chen C, Hung T, Lee C, Wang L, Wu C, Ke C, et al. Berberine protects against neuronal damage via suppression of glia-mediated inflammation in traumatic brain injury. PLoS ONE. 2014;9:e115694 pubmed publisher
  • western blot; mouse; 1:1000; fig 4
Wu C, Hung T, Chen C, Ke C, Lee C, Wang P, et al. Post-injury treatment with 7,8-dihydroxyflavone, a TrkB receptor agonist, protects against experimental traumatic brain injury via PI3K/Akt signaling. PLoS ONE. 2014;9:e113397 pubmed publisher
  • western blot; human
Blaabjerg L, Christensen G, Matsumoto M, van der Meulen T, Huising M, Billestrup N, et al. CRFR1 activation protects against cytokine-induced β-cell death. J Mol Endocrinol. 2014;53:417-27 pubmed publisher
  • western blot; human; fig 1
Riaz A, Zeller K, Johansson S. Receptor-specific mechanisms regulate phosphorylation of AKT at Ser473: role of RICTOR in ?1 integrin-mediated cell survival. PLoS ONE. 2012;7:e32081 pubmed publisher
Lindhurst M, Yourick M, Yu Y, Savage R, Ferrari D, Biesecker L. Repression of AKT signaling by ARQ 092 in cells and tissues from patients with Proteus syndrome. Sci Rep. 2015;5:17162 pubmed publisher
Yang Z, Xie C, Xu W, Liu G, Cao X, Li W, et al. Phosphorylation and inactivation of PTEN at residues Ser380/Thr382/383 induced by Helicobacter pylori promotes gastric epithelial cell survival through PI3K/Akt pathway. Oncotarget. 2015;6:31916-26 pubmed publisher
Carlino M, Fung C, Shahheydari H, Todd J, Boyd S, Irvine M, et al. Preexisting MEK1P124 mutations diminish response to BRAF inhibitors in metastatic melanoma patients. Clin Cancer Res. 2015;21:98-105 pubmed publisher
Xi Y, Chen M, Liu X, Lu Z, Ding Y, Li D. CP-673451, a platelet-derived growth-factor receptor inhibitor, suppresses lung cancer cell proliferation and migration. Onco Targets Ther. 2014;7:1215-21 pubmed publisher
Dufour J, Pommier A, Alves G, de Boussac H, Lours Calet C, Volle D, et al. Lack of liver X receptors leads to cell proliferation in a model of mouse dorsal prostate epithelial cell. PLoS ONE. 2013;8:e58876 pubmed publisher
Luciani D, White S, Widenmaier S, Saran V, Taghizadeh F, Hu X, et al. Bcl-2 and Bcl-xL suppress glucose signaling in pancreatic ?-cells. Diabetes. 2013;62:170-82 pubmed publisher
product information
SKU :
4366P
Product-Name :
Phospho-Bad (Ser136) (D25H8) Rabbit mAb
Size :
40 ul
Price-(USD) :
123 USD
Species-x-Reactivity :
H, M, Mk, (R)
Applications :
Immunoprecipitation
Product-Category :
Apoptosis
Shipping-Temp :
COLD
Storage-Temp :
-20°C
Product-Type :
Monoclonal Antibody
MW :
23
Host :
Rabbit
Target :
Bad (Ser99) phosphate
Primary-Protein :
BAD
Alt-Names :
BAD,BBC2,BBC6,BCL-X/BCL-2 binding protein,BCL2-antagonist of cell death protein,BCL2-associated agonist of cell death,BCL2-binding component 6,BCL2-binding protein,BCL2L8,Bcl-2-binding component 6,Bcl-2-like protein 8,Bcl-XL/Bcl-2-associated death promoter,Bcl2 antagonist of cell death,Bcl2-L-8
company information
Cell Signaling Technology
3 Trask Lane
Danvers, MA 01923
info@cellsignal.com
www.cellsignal.com
8776162355
headquarters: USA
Established in Beverly, MA in 1999, Cell Signaling Technology (CST) is a privately-owned company with over 400 employees worldwide. We are dedicated to providing innovative research tools that are used to help define mechanisms underlying cell function and disease. Since its inception, CST has become the world leader in the production of the highest quality activation-state and total protein antibodies utilized to expand knowledge of cell signaling pathways. Our mission is to deliver the world's highest quality research tools that accelerate progress in biological research and personalized medicine.