product summary
company name :
Cell Signaling Technology
product type :
antibody
product name :
RagA (D8B5) Rabbit mAb
catalog :
4357S
quantity :
100 ul
price :
235 USD
clonality :
monoclonal
host :
rabbit
clone name :
D8B5

The same clone is also sold as:
reactivity :
human, mouse, rat
application :
western blot, immunocytochemistry, immunoprecipitation
more info or order :
Cell Signaling Technology product webpage
citations: 9
Published Application/Species/DilutionReference
  • immunocytochemistry (knockout validation); human; 1:100; fig s10c
  • western blot (knockout validation); human; fig s9e
  • western blot (knockout validation); mouse; 1:1000; fig s1a
Jewell J, Kim Y, Russell R, Yu F, Park H, Plouffe S, et al. Metabolism. Differential regulation of mTORC1 by leucine and glutamine. Science. 2015;347:194-8 pubmed publisher
  • western blot; human; 1:1000; fig s2
Carbonneau M, M Gagné L, Lalonde M, Germain M, Motorina A, Guiot M, et al. The oncometabolite 2-hydroxyglutarate activates the mTOR signalling pathway. Nat Commun. 2016;7:12700 pubmed publisher
  • western blot; human; fig 3
Chen J, Huang C, Zhang B, Yin S, Liang J, Xu C, et al. Mutations of RagA GTPase in mTORC1 Pathway Are Associated with Autosomal Dominant Cataracts. PLoS Genet. 2016;12:e1006090 pubmed publisher
  • western blot; rat; fig 3
Kimball S, Ravi S, Gordon B, Dennis M, Jefferson L. Amino Acid-Induced Activation of mTORC1 in Rat Liver Is Attenuated by Short-Term Consumption of a High-Fat Diet. J Nutr. 2015;145:2496-502 pubmed publisher
  • western blot; human; fig 1
  • immunoprecipitation; human; fig 1
Rebsamen M, Pochini L, Stasyk T, de Araujo M, Galluccio M, Kandasamy R, et al. SLC38A9 is a component of the lysosomal amino acid sensing machinery that controls mTORC1. Nature. 2015;519:477-81 pubmed publisher
  • western blot; human; fig s6
  • immunoprecipitation; human; fig 5
Peng M, Yin N, Li M. Sestrins function as guanine nucleotide dissociation inhibitors for Rag GTPases to control mTORC1 signaling. Cell. 2014;159:122-33 pubmed publisher
  • western blot; human
Oshiro N, Rapley J, Avruch J. Amino acids activate mammalian target of rapamycin (mTOR) complex 1 without changing Rag GTPase guanyl nucleotide charging. J Biol Chem. 2014;289:2658-74 pubmed publisher
  • western blot; human; 1:500
McNulty S, Flint M, Nichol S, Spiropoulou C. Host mTORC1 signaling regulates andes virus replication. J Virol. 2013;87:912-22 pubmed publisher
Yang P, Humphrey S, Fazakerley D, Prior M, Yang G, James D, et al. Re-fraction: a machine learning approach for deterministic identification of protein homologues and splice variants in large-scale MS-based proteomics. J Proteome Res. 2012;11:3035-45 pubmed publisher
product information
SKU :
4357S
Product-Name :
RagA (D8B5) Rabbit mAb
Size :
100 ul
Price-(USD) :
235 USD
Species-x-Reactivity :
H, M, R, Mk
Applications :
Immunoprecipitation
Product-Category :
PI3K / Akt Signaling
Shipping-Temp :
AMBIENT
Storage-Temp :
-20°C
Product-Type :
Monoclonal Antibody
MW :
30
Host :
Rabbit
Target :
RagA
Primary-Protein :
RRAGA
Alt-Names :
Adenovirus E3 14.7 kDa-interacting protein 1,FIP-1,FIP1,RRAGA,Rag A,RagA,Ras-related GTP binding A
more info or order :
Cell Signaling Technology product webpage
company information
Cell Signaling Technology
3 Trask Lane
Danvers, MA 01923
info@cellsignal.com
www.cellsignal.com
8776162355
headquarters: USA
Established in Beverly, MA in 1999, Cell Signaling Technology (CST) is a privately-owned company with over 400 employees worldwide. We are dedicated to providing innovative research tools that are used to help define mechanisms underlying cell function and disease. Since its inception, CST has become the world leader in the production of the highest quality activation-state and total protein antibodies utilized to expand knowledge of cell signaling pathways. Our mission is to deliver the world's highest quality research tools that accelerate progress in biological research and personalized medicine.