RagA (D8B5) Rabbit mAb | Cell Signaling Technology 4357 product information

product summary

company name :

Cell Signaling Technology

product type :

antibody

product name :

RagA (D8B5) Rabbit mAb

catalog :

4357

clonality :

monoclonal

host :

rabbit

conjugate :

nonconjugated

clone name :

D8B5

reactivity :

human, mouse, rat

application :

western blot, immunoprecipitation, western blot knockout validation, immunocytochemistry knockout validation

more info or order :

Cell Signaling Technology product webpage

citations: 13

Published Application/Species/Sample/Dilution	Reference
western blot knockout validation; mouse; 1:1000; fig s1a immunocytochemistry knockout validation; human; 1:100; fig s10c western blot; human; fig s9e	Jewell J, Kim Y, Russell R, Yu F, Park H, Plouffe S, et al. Metabolism. Differential regulation of mTORC1 by leucine and glutamine. Science. 2015;347:194-8 pubmed publisher
western blot knockout validation; human; loading ...; fig 1d	Peng M, Yin N, Li M. SZT2 dictates GATOR control of mTORC1 signalling. Nature. 2017;543:433-437 pubmed publisher
western blot; human; 1:1000; loading ...; fig 4a	Hsu C, Lee E, Gordon K, Paz E, Shen W, Ohnishi K, et al. MAP4K3 mediates amino acid-dependent regulation of autophagy via phosphorylation of TFEB. Nat Commun. 2018;9:942 pubmed publisher
western blot; human; fig 6a	Wu L, Zhou B, Oshiro Rapley N, Li M, Paulo J, Webster C, et al. An Ancient, Unified Mechanism for Metformin Growth Inhibition in C. elegans and Cancer. Cell. 2016;167:1705-1718.e13 pubmed publisher
western blot; human; 1:1000; fig s2	Carbonneau M, M Gagné L, Lalonde M, Germain M, Motorina A, Guiot M, et al. The oncometabolite 2-hydroxyglutarate activates the mTOR signalling pathway. Nat Commun. 2016;7:12700 pubmed publisher
western blot; human; fig 3	Chen J, Huang C, Zhang B, Yin S, Liang J, Xu C, et al. Mutations of RagA GTPase in mTORC1 Pathway Are Associated with Autosomal Dominant Cataracts. PLoS Genet. 2016;12:e1006090 pubmed publisher
western blot; rat; fig 3	Kimball S, Ravi S, Gordon B, Dennis M, Jefferson L. Amino Acid-Induced Activation of mTORC1 in Rat Liver Is Attenuated by Short-Term Consumption of a High-Fat Diet. J Nutr. 2015;145:2496-502 pubmed publisher
immunoprecipitation; human; fig 1 western blot; human; fig 1	Rebsamen M, Pochini L, Stasyk T, de AraÃºjo M, Galluccio M, Kandasamy R, et al. SLC38A9 is a component of the lysosomal amino acid sensing machinery that controls mTORC1. Nature. 2015;519:477-81 pubmed publisher
immunoprecipitation; human; fig 5 western blot; human; fig s6	Peng M, Yin N, Li M. Sestrins function as guanine nucleotide dissociation inhibitors for Rag GTPases to control mTORC1 signaling. Cell. 2014;159:122-133 pubmed publisher
western blot; human	Oshiro N, Rapley J, Avruch J. Amino acids activate mammalian target of rapamycin (mTOR) complex 1 without changing Rag GTPase guanyl nucleotide charging. J Biol Chem. 2014;289:2658-74 pubmed publisher
western blot; human; 1:500	McNulty S, Flint M, Nichol S, Spiropoulou C. Host mTORC1 signaling regulates andes virus replication. J Virol. 2013;87:912-22 pubmed publisher
	Zheng K, Jiang Y, Liao C, Hu X, Li Y, Zeng Y, et al. NOX2-Mediated TFEB Activation and Vacuolization Regulate Lysosome-Associated Cell Death Induced by Gypenoside L, a Saponin Isolated from Gynostemma pentaphyllum. J Agric Food Chem. 2017;65:6625-6637 pubmed publisher
	Yang P, Humphrey S, Fazakerley D, Prior M, Yang G, James D, et al. Re-fraction: a machine learning approach for deterministic identification of protein homologues and splice variants in large-scale MS-based proteomics. J Proteome Res. 2012;11:3035-45 pubmed publisher

product information

SKU :

4357S

Product-Name :

RagA (D8B5) Rabbit mAb

Size :

100 ul

Price-(USD) :

235 USD

Species-x-Reactivity :

H, M, R, Mk

Applications :

Immunoprecipitation

Product-Category :

PI3K / Akt Signaling

Shipping-Temp :

AMBIENT

Storage-Temp :

-20°C

Product-Type :

Monoclonal Antibody

MW :

Host :

Rabbit

Target :

RagA

Primary-Protein :

RRAGA

Alt-Names :

Adenovirus E3 14.7 kDa-interacting protein 1,FIP-1,FIP1,RRAGA,Rag A,RagA,Ras-related GTP binding A

more info or order :

Cell Signaling Technology product webpage