product summary
company name :
Cell Signaling Technology
product type :
antibody
product name :
GSK-3α (D80E6) Rabbit mAb
catalog :
4337
clonality :
monoclonal
host :
rabbit
conjugate :
nonconjugated
clone name :
D80E6
reactivity :
human, mouse, rat
application :
western blot, immunoprecipitation, western blot knockout validation
citations: 11
Published Application/Species/Sample/DilutionReference
  • western blot knockout validation; mouse; 1:1000; fig 1a
Chen X, Wang R, Liu X, Wu Y, Zhou T, Yang Y, et al. A Chemical-Genetic Approach Reveals the Distinct Roles of GSK3? and GSK3? in Regulating Embryonic Stem Cell Fate. Dev Cell. 2017;43:563-576.e4 pubmed publisher
  • western blot; mouse; loading ...; fig 3d
Markussen L, Winther S, Wicksteed B, Hansen J. GSK3 is a negative regulator of the thermogenic program in brown adipocytes. Sci Rep. 2018;8:3469 pubmed publisher
  • western blot; mouse; loading ...; fig 2c
Pal M, Gupta S. Testosterone supplementation improves glucose homeostasis despite increasing hepatic insulin resistance in male mouse model of type 2 diabetes mellitus. Nutr Diabetes. 2016;6:e236 pubmed publisher
  • western blot; mouse; loading ...; fig 7a
Qin Y, Liu Y, Hao W, Decker Y, Tomic I, Menger M, et al. Stimulation of TLR4 Attenuates Alzheimer's Disease-Related Symptoms and Pathology in Tau-Transgenic Mice. J Immunol. 2016;197:3281-3292 pubmed
  • western blot; mouse; loading ...; fig 6b
Chelko S, Asimaki A, Andersen P, Bedja D, Amat Alarcon N, Demazumder D, et al. Central role for GSK3β in the pathogenesis of arrhythmogenic cardiomyopathy. JCI Insight. 2016;1: pubmed publisher
  • western blot; mouse; fig 3f
Finch Edmondson M, Strauss R, Passman A, Sudol M, Yeoh G, Callus B. TAZ Protein Accumulation Is Negatively Regulated by YAP Abundance in Mammalian Cells. J Biol Chem. 2015;290:27928-38 pubmed publisher
  • western blot; human
Choi J, Landrette S, Wang T, Evans P, Bacchiocchi A, Bjornson R, et al. Identification of PLX4032-resistance mechanisms and implications for novel RAF inhibitors. Pigment Cell Melanoma Res. 2014;27:253-62 pubmed publisher
  • western blot; mouse; 1:1000
Udagawa T, Farny N, Jakovcevski M, Kaphzan H, Alarcon J, Anilkumar S, et al. Genetic and acute CPEB1 depletion ameliorate fragile X pathophysiology. Nat Med. 2013;19:1473-7 pubmed publisher
  • western blot; human; 1:2000
Kao C, Hsu Y, Liu J, Lee D, Chung Y, Chiu I. The mood stabilizer valproate activates human FGF1 gene promoter through inhibiting HDAC and GSK-3 activities. J Neurochem. 2013;126:4-18 pubmed publisher
Nakamura M, Liu T, Husain S, Zhai P, Warren J, Hsu C, et al. Glycogen Synthase Kinase-3α Promotes Fatty Acid Uptake and Lipotoxic Cardiomyopathy. Cell Metab. 2019;29:1119-1134.e12 pubmed publisher
Ji L, Jiang B, Jiang X, Charlat O, Chen A, Mickanin C, et al. The SIAH E3 ubiquitin ligases promote Wnt/?-catenin signaling through mediating Wnt-induced Axin degradation. Genes Dev. 2017;31:904-915 pubmed publisher
product information
SKU :
4337S
Product-Name :
GSK-3α (D80E6) Rabbit mAb
Size :
100 ul
Price-(USD) :
235 USD
Species-x-Reactivity :
H, M, R, Hm, Mk
Applications :
Immunoprecipitation
Product-Category :
PI3K / Akt Signaling
Shipping-Temp :
AMBIENT
Storage-Temp :
-20°C
Product-Type :
Monoclonal Antibody
MW :
51
Host :
Rabbit
Target :
GSK3-alpha
Primary-Protein :
GSK3A
Alt-Names :
DKFZp686D0638,GSK-3 alpha,GSK3A,Glycogen synthase kinase-3 alpha,glycogen synthase kinase 3 alpha
company information
Cell Signaling Technology
3 Trask Lane
Danvers, MA 01923
info@cellsignal.com
https://www.cellsignal.com
8776162355
headquarters: USA
Established in Beverly, MA in 1999, Cell Signaling Technology (CST) is a privately-owned company with over 400 employees worldwide. We are dedicated to providing innovative research tools that are used to help define mechanisms underlying cell function and disease. Since its inception, CST has become the world leader in the production of the highest quality activation-state and total protein antibodies utilized to expand knowledge of cell signaling pathways. Our mission is to deliver the world's highest quality research tools that accelerate progress in biological research and personalized medicine.