Tuberin/TSC2 (D93F12) XP® Rabbit mAb | Cell Signaling Technology 4308S product information

product summary

company name :

Cell Signaling Technology

product type :

antibody

product name :

Tuberin/TSC2 (D93F12) XP® Rabbit mAb

catalog :

4308S

quantity :

100 ul

price :

260 USD

clonality :

monoclonal

host :

rabbit

reactivity :

human, mouse, rat

application :

western blot, immunocytochemistry, immunoprecipitation

more info or order :

Cell Signaling Technology product webpage

citations: 12

Published Application/Species/Dilution	Reference
western blot; human; fig 5 western blot; mouse; fig 5	Vural A, Al-Khodor S, Cheung G, Shi C, Srinivasan L, McQuiston T, et al. Activator of G-Protein Signaling 3-Induced Lysosomal Biogenesis Limits Macrophage Intracellular Bacterial Infection. J Immunol. 2016;196:846-56 pubmed publisher
western blot; mouse; 1:1000; fig 3	Hakim S, Dyson J, Feeney S, Davies E, Sriratana A, Koenig M, et al. Inpp5e suppresses polycystic kidney disease via inhibition of PI3K/Akt-dependent mTORC1 signaling. Hum Mol Genet. 2016;: pubmed
immunocytochemistry; human; 1:800; fig 5	Agarwal S, Bell C, Taylor S, Moran R. p53 Deletion or Hotspot Mutations Enhance mTORC1 Activity by Altering Lysosomal Dynamics of TSC2 and Rheb. Mol Cancer Res. 2016;14:66-77 pubmed publisher
western blot; human; 1:1000; fig 4 western blot; mouse; 1:1000; fig 4	Bento C, Ashkenazi A, Jimenez-Sanchez M, Rubinsztein D. The Parkinson's disease-associated genes ATP13A2 and SYT11 regulate autophagy via a common pathway. Nat Commun. 2016;7:11803 pubmed publisher
western blot; human; 1:1000	Espana-Agusti J, Tuveson D, Adams D, Matakidou A. A minimally invasive, lentiviral based method for the rapid and sustained genetic manipulation of renal tubules. Sci Rep. 2015;5:11061 pubmed publisher
western blot; rat; 1:1000	Harris-White M, Ferbas K, Johnson M, Eslami P, Poteshkina A, Venkova K, et al. A cell-penetrating ester of the neural metabolite lanthionine ketimine stimulates autophagy through the mTORC1 pathway: Evidence for a mechanism of action with pharmacological implications for neurodegenerative pathologies. Neurobiol Dis. 2015;84:60-8 pubmed publisher
western blot; human	Verma R, Marchese A. The endosomal sorting complex required for transport pathway mediates chemokine receptor CXCR4-promoted lysosomal degradation of the mammalian target of rapamycin antagonist DEPTOR. J Biol Chem. 2015;290:6810-24 pubmed publisher
western blot; human; fig 2	Ye Z, Al-Aidaroos A, Park J, Yuen H, Zhang S, Gupta A, et al. PRL-3 activates mTORC1 in Cancer Progression. Sci Rep. 2015;5:17046 pubmed publisher
	Wu J, Shin J, Xie D, Wang H, Gao J, Zhong X. Tuberous sclerosis 1 promotes invariant NKT cell anergy and inhibits invariant NKT cell-mediated antitumor immunity. J Immunol. 2014;192:2643-50 pubmed publisher
	Park J, Arakawa-Takeuchi S, Jinno S, Okayama H. Rho-associated kinase connects a cell cycle-controlling anchorage signal to the mammalian target of rapamycin pathway. J Biol Chem. 2011;286:23132-41 pubmed publisher
	Dibble C, Elis W, Menon S, Qin W, Klekota J, Asara J, et al. TBC1D7 is a third subunit of the TSC1-TSC2 complex upstream of mTORC1. Mol Cell. 2012;47:535-46 pubmed publisher
	Goto J, Talos D, Klein P, Qin W, Chekaluk Y, Anderl S, et al. Regulable neural progenitor-specific Tsc1 loss yields giant cells with organellar dysfunction in a model of tuberous sclerosis complex. Proc Natl Acad Sci U S A. 2011;108:E1070-9 pubmed publisher

product information

SKU :

4308S

Product-Name :

Tuberin/TSC2 (D93F12) XP® Rabbit mAb

Size :

100 ul

Price-(USD) :

260 USD

Species-x-Reactivity :

H, M, R, Hm, Mk

Applications :

Immunofluorescence (Immunocytochemistry)

Product-Category :

PI3K / Akt Signaling

Shipping-Temp :

AMBIENT

Storage-Temp :

-20°C

Product-Type :

Monoclonal Antibody

MW :

200

Host :

Rabbit

Target :

Tuberin/TSC2

Primary-Protein :

TSC2

Alt-Names :

FLJ43106,LAM,TSC2,TSC4,Tuberin,Tuberous sclerosis 2 protein,tuberous sclerosis 2

more info or order :

Cell Signaling Technology product webpage